Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Po Ku Chen"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
ObjectiveThe risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA) remains inadequately defined. Consequently, this study aims to evaluate the predictive value of remnant cholesterol (RC) for assessing CVD risk in RA patient
Externí odkaz:
https://doaj.org/article/4fbc3d201cdd4f419336cd0b35d7518a
Autor:
Po-Ku Chen, Wei-Fan Hsu, Cheng-Yuan Peng, Tsai-Ling Liao, Shih-Hsin Chang, Hsin-Hua Chen, Chu-Huang Chen, Der-Yuan Chen
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundNon-alcoholic fatty liver disease (NAFLD) is prevalent among rheumatoid arthritis (RA) patients, but its pathogenesis has rarely been explored. Galectin-9 (Gal-9) interacts with T cell immunoglobulin and mucin-containing-molecule-3 (TIM-3)
Externí odkaz:
https://doaj.org/article/1261a7d2a7604f22b6149756fd279616
Autor:
Yi-Ming Chen, Tsai-Ling Liao, Hsin-Hua Chen, Der-Yuan Chen, Kuo-Tung Tang, Ching-Heng Lin, Wei-Li Ho, Po-Ku Chen, Shih-Hsin Chang
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Background Although the non-alcoholic fatty liver disease (NAFLD) is prevalent in the general population, NAFLD risk in newly diagnosed rheumatoid arthritis (RA) has rarely been explored. In this population-based cohort, we examined NAFLD risk in pat
Externí odkaz:
https://doaj.org/article/9348fe54785943b59d04bd48850c5159
Autor:
Po-Ku Chen, Yi-Ming Chen, Hsin-Hua Chen, Tsai-Ling Liao, Shih-Hsin Chang, Kai-Jieh Yeo, Po-Hao Huang, Der-Yuan Chen
Publikováno v:
Microorganisms, Vol 12, Iss 5, p 974 (2024)
Anti-interferon (IFN)-γ autoantibodies are linked to varicella zoster virus (VZV) infection. Given the elevated risks of herpes zoster (HZ) in rheumatoid arthritis (RA) patients treated with Janus kinase inhibitors (JAKis), we aimed to examine the r
Externí odkaz:
https://doaj.org/article/969df6aa23bc45e79e0ba3f1017dfe29
Autor:
Po-Ku Chen, Kai-Jieh Yeo, Shih-Hsin Chang, Tsai-Ling Liao, Chia-Hui Chou, Joung-Liang Lan, Ching-Kun Chang, Der-Yuan Chen
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Background Neutralizing anti-interferon (IFN)-γ autoantibodies are linked to adult-onset immunodeficiency and opportunistic infections. Methods To explore whether anti-IFN-γ autoantibodies are associated with disease severity of coronaviru
Externí odkaz:
https://doaj.org/article/763eb65fa9a44d97b1267684d7a929d7
Autor:
Shih-Hsin Chang, Teng-Chieh Hsu, Po-Hao Huang, Chien-Chung Huang, Kai-Jieh Yeo, Wei-Jhe Hong, Po-Ku Chen, Yun-Hsieh Lin, Joung-Liang Lan, Der-Yuan Chen
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 2, Pp 343-355 (2022)
Abstract Introduction The diagnosis of adult-onset Still’s disease (AOSD) is often delayed due to its clinical heterogeneity and lack of pathognomic features. Hence, there is an unmet need for an efficient diagnostic process. The major aim of this
Externí odkaz:
https://doaj.org/article/29806d468c61411798e3c5cc43e040fd
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
ObjectiveNeutralizing anti-interferon (IFN)-γ autoantibodies are linked to opportunistic infections (OIs). To explore the association between anti-IFN-γ autoantibodies and OIs in patients with adult-onset Still's disease (AOSD), we aimed to examine
Externí odkaz:
https://doaj.org/article/0c23bb4aeb2d41ebb57ec566ca2d4afa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Modulation of miRNAs and neutrophil extracellular traps (NETs) formation are both implicated in inflammatory disorders. Adult-onset Still’s disease (AOSD) is a systemic autoinflammatory disease with neutrophilic leukocytosis and unknown et
Externí odkaz:
https://doaj.org/article/a0f2a73a1f5b4c26b72c48c36aa6cdd4
Autor:
Po-Ku Chen, Joung-Liang Lan, Po-Hao Huang, Jye-Lin Hsu, Ching-Kun Chang, Ni Tien, Hui-Ju Lin, Der-Yuan Chen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundHyperinflammation with dysregulated production of galectins and cytokines may develop in COVID-19 or adult-onset Still’s disease (AOSD). Given the similar clinical features in both diseases, it is necessary to identify biomarkers that can
Externí odkaz:
https://doaj.org/article/f30916835a134af6901e500eea779db8
Autor:
Po-Ku Chen, Joung-Liang Lan, Yi-Ming Chen, Hsin-Hua Chen, Shih-Hsin Chang, Chia-Min Chung, Nurul H. Rutt, Ti-Myen Tan, Raja Nurashirin Raja Mamat, Nur Diana Anuar, Jonathan M. Blackburn, Der-Yuan Chen
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Anti-drug antibody (ADAb) development is associated with secondary therapeutic failure in biologic-treated rheumatoid arthritis (RA) patients. With a treat-to-target goal, we aimed to identify biomarkers for predicting ADAb development and therapeuti
Externí odkaz:
https://doaj.org/article/cf7d1144e6b9487a9fdd196f98b05e13