Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Po C. Chan"'
Autor:
Abraham Nyska, Po C. Chan, Barney Sparrow, Milton R. Hejtmancik, Gregory S. Travlos, Rajendra S. Chhabra, Laurene M. Fomby, Mamta Behl
Publikováno v:
Food and Chemical Toxicology. 49:2820-2829
Kava Kava is an herbal supplement used as an alternative to antianxiety drugs. Although some reports suggest an association of Kava Kava with hepatotoxicity , it continues to be used in the United States due to lack of toxicity characterization. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c1fead0c8c8ff44159f9f3fdb6ea56
https://doi.org/10.1016/j.fct.2011.07.067
https://doi.org/10.1016/j.fct.2011.07.067
Autor:
Grace E. Kissling, Yuval Ramot, Po C. Chan, Abraham Nyska, David E. Malarkey, Pamela E. Blackshear, Greg Travlos
Publikováno v:
Toxicologic Pathology. 38:1070-1084
The toxicity of green tea extract (GTE) was evaluated in 14-week gavage studies in male and female F344/NTac rats and B6C3F1 mice at doses up to 1,000 mg/kg. In the rats, no treatment-related mortality was noted. In the mice, treatment-related mortal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2adc412b9b976b2bfc647c65333ffe35
https://doi.org/10.1177/0192623310382437
https://doi.org/10.1177/0192623310382437
Publikováno v:
Archives of Toxicology. 77:511-520
2,4-Hexadienal (2,4-Hx) was studied for its toxicity and carcinogenicity because of its alpha, beta-unsaturated aldehyde structure and potential link between exposure to lipid peroxidation products in the diet and human malignancies. Male and female
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412dc048497e22f62572255313ba918e
https://doi.org/10.1007/s00204-003-0481-8
https://doi.org/10.1007/s00204-003-0481-8
Autor:
Rodney A. Miller, Jeffrey A. Dill, Joseph H. Roycroft, Roger A. Renne, Leo T. Burka, Alfred F. Fuciarelli, Po C. Chan, Kathy M. Gideon, Kyeonghee Monica Lee
Publikováno v:
Toxicological Sciences. 72:223-234
Decalin (decahydronaphthalene) is a widely used industrial solvent known to cause male rat-specific alpha2u-globulin nephropathy. In this project, 13-week and two-year inhalation studies of decalin were conducted consecutively in both sexes of F344/N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb414df138228f4a10fc96c65d0a692
https://doi.org/10.1093/toxsci/kfg028
https://doi.org/10.1093/toxsci/kfg028
Autor:
Abraham Nyska, David G. Allen, Connie A. Cummings, Shyamal D. Peddada, Carolyn F. Moyer, Cindy R. Moomaw, Po C. Chan, Julie F. Foley, David E. Malarkey, Robert R. Maronpot, Greg Travlos
Publikováno v:
Toxicology and Applied Pharmacology. 184:153-164
Riddelliineis a naturally occurring pyrrolizidine alkaloid found in certain poisonous rangeland plants of the western United States. In National Toxicology Program 2-year studies, riddelliine induced high incidences of hemangiosarcoma in the liver of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ccc863f8e449db6d9c04206174bd768
https://doi.org/10.1006/taap.2002.9485
https://doi.org/10.1006/taap.2002.9485
Publikováno v:
Archives of Toxicology. 75:618-624
2,4-Hexadienal (2,4-Hx), an unsaturated aldehyde formed by in vivo and in vitro peroxidation of unsaturated lipid induced, in National Toxicology Program (NTP) gavage studies of F344 rats, forestomach hyperplasia in 13-week and 2-year exposures and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c4c83384106ef9eb6110375ea0b585
https://doi.org/10.1007/s002040100278
https://doi.org/10.1007/s002040100278
Publikováno v:
Archives of Toxicology
The toxicity and carcinogenic potential of theophylline (an alkaloid bronchodilator drug) was investigated in male and female F344/N rats in 16-day, 14-week, and 2-year gavage and feeding studies. In 16-day studies, rats were fed diets containing 0,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a968d8a537e17c9d48d378b3531024a0
https://doi.org/10.1007/s002040050567
https://doi.org/10.1007/s002040050567
Publikováno v:
Toxicology Letters. 99:23-32
Carcinogenesis studies of ethylbenzene were conducted because of its extensive use as a solvent and because it is structurally similar to the known carcinogen benzene. Groups of 50 male and 50 female Fischer rats and B6C3F1 mice were exposed to ethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139e96b1e37cee6c8fd887b043732fa0
https://doi.org/10.1016/s0378-4274(98)00133-7
https://doi.org/10.1016/s0378-4274(98)00133-7
Autor:
Po C. Chan, James Huff
Publikováno v:
Journal of Environmental Science and Health, Part C. 15:83-122
(1997). Arsenic carcinogenesis in animals and in humans: Mechanistic, experimental, and epidemiological evidence. Journal of Environmental Science and Health, Part C: Vol. 15, No. 2, pp. 83-122.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d8960daf384b8526510a4084da6ec4c
https://doi.org/10.1080/10590509709373492
https://doi.org/10.1080/10590509709373492
Autor:
Cynthia Smith, Cynthia V. Rider, Gregory S. Travlos, Po C. Chan, Grace E. Kissling, Abraham Nyska, Laurene M. Fomby, Milton R. Hejtmancik, Michael J. Ryan, James P. Morrison, Linda Kooistra, Michelle C. Cora, Curtis A. Colleton
Ginkgo biloba extract (GBE) is a popular herbal supplement that is used to improve circulation and brain function. In spite of widespread human exposure to relatively high doses over potentially long periods of time, there is a paucity of data from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8c1019fd8466dea51cdf111047a0b1
https://europepmc.org/articles/PMC3929544/
https://europepmc.org/articles/PMC3929544/
