Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Po‐Chen Chu"'
Autor:
Kun-Chang Wu, Hsiang-Wen Lin, Po-Chen Chu, Chia-Ing Li, Hsiang-Han Kao, Chih-Hsueh Lin, Yu-Jung Cheng
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Disuse muscle atrophy occurs consequent to prolonged limb immobility or bed rest, which represents an unmet medical need. As existing animal models of limb immobilization often cause skin erosion, edema, and other untoward effects, we here r
Externí odkaz:
https://doaj.org/article/9d2dca3d1890405e9e8782c946a67828
Autor:
Kun‐Chang Wu, Po‐Chen Chu, Yu‐Jung Cheng, Chia‐Ing Li, Jingkui Tian, Hsing‐Yu Wu, Szu‐Hsien Wu, Yi‐Chun Lai, Hsiang‐Han Kao, Ao‐Lin Hsu, Hsiang‐Wen Lin, Chih‐Hsueh Lin
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2073-2087 (2022)
Abstract Background Despite recent advances in understanding the pathophysiology of cancer cachexia, prevention/treatment of this debilitating disease remains an unmet medical need. Methods We developed an integrated, multi‐tiered strategy involvin
Externí odkaz:
https://doaj.org/article/e52515a1b0c4493788a292f72d4c7817
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract In this study, we interrogated the mechanism by which the immunosuppressant FTY720 mediates anticancer effects in oral squamous cell carcinoma (OSCC) cells. FTY720 differentially suppressed the viability of the OSCC cell lines SCC4, SCC25, a
Externí odkaz:
https://doaj.org/article/c320f44d950445378008bb0d47854a3b
Autor:
Peng-Chan Lin, Yi-Fang Yang, Yu-Chang Tyan, Eric S L Hsiao, Po-Chen Chu, Chung-Ta Lee, Jenq-Chang Lee, Yi-Ming Arthur Chen, Pao-Chi Liao
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158844 (2016)
Colorectal cancer is the most common form of cancer in the world, and the five-year survival rate is estimated to be almost 90% in the early stages. Therefore, the identification of potential biomarkers to assess the prognosis of early stage colorect
Externí odkaz:
https://doaj.org/article/853b15c447034716b9b4e05c89283543
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47298 (2012)
Substantial evidence supports the oncogenic role of the E3 ubiquitin ligase S-phase kinase-associated protein 2 (Skp2) in many types of cancers through its ability to target a broad range of signaling effectors for ubiquitination. Thus, this oncogeni
Externí odkaz:
https://doaj.org/article/fb261384b1ab4fb8bf57b413a1d80acc
Autor:
Chia-Hsin Chen, Po-Chen Chu, Liekyeow Lee, Huang-Wei Lien, Tse-Ling Lin, Chi-Chen Fan, Peter Chi, Chang-Jen Huang, Mau-Sun Chang
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33538 (2012)
Human p29 is a putative component of spliceosomes, but its role in pre-mRNA is elusive. By siRNA knockdown and stable overexpression, we demonstrated that human p29 is involved in DNA damage response and Fanconi anemia pathway in cultured cells. In t
Externí odkaz:
https://doaj.org/article/3e56f3b86e8d474f85559f58a3283d2c
Autor:
Po-Chen Chu, 朱伯振
98
Human p29 protein was initially identified as a GCIP (Grab2 cyclin D interacting protein)-interaction protein and its function is largely undetermined. In this study, we found that p29 associated with chromatin, interacted with MCM3, and loca
Human p29 protein was initially identified as a GCIP (Grab2 cyclin D interacting protein)-interaction protein and its function is largely undetermined. In this study, we found that p29 associated with chromatin, interacted with MCM3, and loca
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/65284301917900492500
Autor:
Ching-Shih Chen, Samuel K. Kulp, Steven K. Clinton, Tiffany Yang, Dasheng Wang, Brad Bolon, Jennifer M. Thomas-Ahner, Po-Chen Chu, Lisa D. Berman-Booty
PDF file - 213K, Supplemental Table 1 is a table that lists the average sum of the adjusted lesion scores (SALS) for each lobe of the prostate, as well as the average score for the most severe and most common lesion in each lobe. Supplemental tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0067f1e3cde41b7351989c36780f8662
https://doi.org/10.1158/1940-6207.22524563.v1
https://doi.org/10.1158/1940-6207.22524563.v1
Autor:
Ching-Shih Chen, Samuel K. Kulp, Steven K. Clinton, Tiffany Yang, Dasheng Wang, Brad Bolon, Jennifer M. Thomas-Ahner, Po-Chen Chu, Lisa D. Berman-Booty
PDF file - 120K, This is a more detailed discussion of the microarray data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5313a5d5b947a3761207acd62b2be5
https://doi.org/10.1158/1940-6207.22524566.v1
https://doi.org/10.1158/1940-6207.22524566.v1
Autor:
Ching-Shih Chen, Samuel K. Kulp, Steven K. Clinton, Tiffany Yang, Dasheng Wang, Brad Bolon, Jennifer M. Thomas-Ahner, Po-Chen Chu, Lisa D. Berman-Booty
Cells undergoing malignant transformation often exhibit a shift in cellular metabolism from oxidative phosphorylation to glycolysis. This glycolytic shift, called the Warburg effect, provides a mechanistic basis for targeting glycolysis to suppress c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d751ce17aa777387a9eef6b77cba0aa
https://doi.org/10.1158/1940-6207.c.6544310.v1
https://doi.org/10.1158/1940-6207.c.6544310.v1