Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pmj McLaughlin"'
Autor:
PMJ McLaughlin, M Klar, F Heitz, TA Zwimpfer, G Dutilh, M Vetter, C Marth, A du Bois, C Schade-Brittinger, A Reuss, C Bommer, C Kurzeder, V Heinzelmann
Publikováno v:
64. Kongress der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe e. V..
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1c96e888ad7869c3b2dfe14fddef6ba
https://doi.org/10.1055/s-0042-1756948
https://doi.org/10.1055/s-0042-1756948
Publikováno v:
Molecular Genetics and Metabolism. 92:299-307
Pompe disease is a rare autosomal recessive lysosomal storage disease caused by deficiency of acid-alpha-glucosidase (GAA). This deficiency results in glycogen accumulation in the lysosomes, leading to lysosomal swelling, cellular damage and organ dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8526158955a1278fe3f9f7efd7128165
https://doi.org/10.1016/j.ymgme.2007.07.009
https://doi.org/10.1016/j.ymgme.2007.07.009
Autor:
SJ van Eert, Pmj McLaughlin, Hidde J. Haisma, David T. Curiel, WM Gommans, Masato Yamamoto, Marco Harmsen, Marianne G. Rots
Publikováno v:
Cancer Gene Therapy, 13(2), 150-158. Nature Publishing Group
Adenoviral vectors are widely used in cancer gene therapy. After systemic administration however, the majority of the virus homes to the liver and the expressed transgene may cause hepatotoxicity. To restrict transgene expression to tumor cells, tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b333bed9b9dc23aa42883f4b0330ade2
https://doi.org/10.1038/sj.cgt.7700882
https://doi.org/10.1038/sj.cgt.7700882
Autor:
Marcel H. J. Ruiters, de Marieke Groot, Wha Dokter, Maria Brinker, de Louis Leij, Chcm Buys, Klaas Kok, Pmj McLaughlin, H van der Molen, BJ Kroesen
Publikováno v:
Cancer Immunology Immunotherapy, 48(6), 303-311. SPRINGER
The human pancarcinoma-associated epithelial glycoprotein-2 (EGP-2), also known as 17-1A or EpCAM, is a 38-kDa transmembrane antigen, commonly used for targeted immunotherapy of carcinomas. Although strongly expressed by most carcinomas, EGP-2 is als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c1368e59bad30f1a526425ca3f95c5
https://doi.org/10.1007/s002620050579
https://doi.org/10.1007/s002620050579
Autor:
van Harry Goor, Marco Harmsen, van Gooitzen Dam, de Louis Leij, Monika Trzpis, Eliane R. Popa, Maria Brinker, Pmj McLaughlin
Publikováno v:
JOURNAL OF PATHOLOGY, 216(2), 201-208. Wiley
The human epithelial cell adhesion molecule (hEpCAM) is involved in epithelial morphogenesis and repair of epithelial tissues. We hypothesized that changes in hEpCAM expression ill vivo correlate with regeneration of renal epithelia after ischaemia/r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574972a07fafae26ad592c64f93af462
https://research.rug.nl/en/publications/61c0b346-b58a-4681-a1b5-55e8efa402dc
https://research.rug.nl/en/publications/61c0b346-b58a-4681-a1b5-55e8efa402dc
Autor:
Johanna A. C. Schalk, Marianne G. Rots, Pmj McLaughlin, Hidde J. Haisma, Geny M. M. Groothuis, WM Gommans
Publikováno v:
Journal of Controlled Release, 117(1), 1-10. Elsevier Bedrijfsinformatie b.v.
Although some successes have been reported using adenoviral vectors for the treatment of cancer, adenoviral cancer gene therapy is still hampered by the lack of sufficient tumor cell killing. To increase the efficiency, adenoviruses have been modifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99dfb56eacdf3d3c66cfab2b7b0eefb
https://research.rug.nl/en/publications/4434a435-513d-4d78-af28-ac859fa46baa
https://research.rug.nl/en/publications/4434a435-513d-4d78-af28-ac859fa46baa
Autor:
David T. Curiel, SJ van Eert, Masato Yamamoto, Marco Harmsen, Pmj McLaughlin, Marianne G. Rots, Hidde J. Haisma, WM Gommans
Publikováno v:
Molecular Therapy. 9:S112
Adenoviruses are widely used as vectors to deliver genetic material into cells. Although these vectors are currently the most efficient vectors used, they are not specific and not efficient enough to result in a good clinical outcome in the treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e87b4b3d2141bbbb61ab240a064e762e
https://doi.org/10.1016/j.ymthe.2004.06.235
https://doi.org/10.1016/j.ymthe.2004.06.235
Autor:
McLaughlin PMJ; Department of Gynecology and Gynecologic Oncology, University Hospital Basel, Basel, Switzerland., Klar M; Department of Gynecology and Gynecologic Oncology, University Hospital Freiburg, Freiburg, Germany., Zwimpfer TA; Department of Gynecology and Gynecologic Oncology, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland., Dutilh G; Department of Clinical Research, Clinical Trial Unit, University of Basel Hospital, Basel, Switzerland., Vetter M; Department of Medical Oncology, Hematology and Immunotherapy, Cantonal Hospital Baselland, Medical University Hospital, Liestal, Switzerland., Marth C; Department of Gynecology and Gynecologic Oncology, University Hospital Innsbruck, Innsbruck, Austria., du Bois A; KEM: Evangelische Kliniken Essen Mitte, Essen, Germany., Schade-Brittinger C; Coordinating Center for Clinical Trials, Philipps University Marburg, Wiesbaden, Germany., Reuss A; Coordinating Center for Clinical Trials, Philipps University Marburg, Wiesbaden, Germany., Bommer C; Department of Gynecology and Gynecologic Oncology, University Hospital Basel, Basel, Switzerland., Kurzeder C; Department of Gynecology and Gynecologic Oncology, University Hospital Basel, Basel, Switzerland., Heinzelmann-Schwarz V; Department of Gynecology and Gynecologic Oncology, University Hospital Basel, Basel, Switzerland. viola.heinzelmann@usb.ch.; Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland. viola.heinzelmann@usb.ch.
Publikováno v:
BMC cancer [BMC Cancer] 2022 May 06; Vol. 22 (1), pp. 508. Date of Electronic Publication: 2022 May 06.
Autor:
van der Gun BTF; Department of Pathology and Laboratory Medicine, Section Medical Biology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Wasserkort R; Epigenomics AG, Kleine Praesidentenstrasse 1, D-10178, Berlin, Germany., Monami A; Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52056 Aachen, Germany., Jeltsch A; School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, D-28725 Bremen, Germany., Raskó T; Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, 6726 Szeged, Temesvári krt. 62, Hungary., Ślaska-Kiss K; Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, 6726 Szeged, Temesvári krt. 62, Hungary., Cortese R; Epigenomics AG, Kleine Praesidentenstrasse 1, D-10178, Berlin, Germany., Rots MG; Department of Pathology and Laboratory Medicine, Section Medical Biology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., de Leij LFMH; Department of Pathology and Laboratory Medicine, Section Medical Biology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Ruiters MHJ; Department of Pathology and Laboratory Medicine, Section Medical Biology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Kiss A; Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, 6726 Szeged, Temesvári krt. 62, Hungary., Weinhold E; Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52056 Aachen, Germany., McLaughlin PMJ; Department of Pathology and Laboratory Medicine, Section Medical Biology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
Publikováno v:
International journal of cancer [Int J Cancer] 2008 Jul 15; Vol. 123 (2), pp. 484-489.