Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Plugina La"'
Publikováno v:
DNA Repair. 10:16-23
The double-strand break (DSB) repair via homologous recombination is generally construed as a high-fidelity process. However, some molecular genetic observations show that the recombination and the recombinational DSB repair may be mutagenic and even
Double-Strand Break Repair in Bacteriophage T4: Recombination Effects of 3′–5′ Exonuclease Mutations
Publikováno v:
Genetics. 174:1729-1736
The role of 3′–5′ exonucleases in double-strand break (DSB)-promoted recombination was studied in crosses of bacteriophage T4, in which DSBs were induced site specifically within the rIIB gene by SegC endonuclease in the DNA of only one of the
Publikováno v:
DNA repair. 10(4)
In previous papers we described an extra recombination mechanism in T4 phage, which contributed to general recombination only when particular mutations were used as geneticmarkers (high recombination or HR markers), whereas it was practically inactiv
Autor:
V P Shcherbakov, Plugina La
Publikováno v:
Genetics. 128:673-685
Distance- as well as marker-dependence of genetic recombination of bacteriophage T4 was studied in crosses between rIIB mutants with known base sequences. The notion of a "basic recombination," which is the recombination within distances shorter than
Publikováno v:
DNA repair. 5(7)
Coordination of DNA ends during double-strand break (DSB) repair was studied in crosses of bacteriophage T4 in which DSBs were induced site-specifically by SegC endonuclease in the DNA of only one of the parents. Coupling of the genetic exchanges to
Autor:
Michael G. Shlyapnikov, Igor Granovsky, Konstantin Pyatkov, Olga Shubina, Tamara Shcherbakova, V P Shcherbakov, Plugina La, Svetlana V. Sizova
Publikováno v:
Genetics. 162(2)
A model system for studying double-strand-break (DSB)-induced genetic recombination in vivo based on the ets1 segCΔ strain of bacteriophage T4 was developed. The ets1, a 66-bp DNA fragment of phage T2L containing the cleavage site for the T4 SegC si
Publikováno v:
Genetics. 140(1)
Recombinational effects of the antimutator allele tsL42 of gene 43 of phage T4, encoding DNA polymerase, were studied in crosses between rIIB mutants. Recombination under tsL42-restricted conditions differed from the normal one in several respects: (
Publikováno v:
Genetics. 131(4)
To reveal the structure of penultimate DNA intermediates in T4 bacteriophage recombination, resolution of which produces free recombinant molecules, a single-burst analysis of the recombinant progeny was made in multifactor crosses, enabling one to d
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Autor:
O. I. Efremova, Plugina La, V P Shcherbakov, Elena Kudryashova, S. T. Sizova, Oleg G. Toompuu
Publikováno v:
Genetics. 102:615-625
In standard crosses, some rIIB mutants of T4 phage were found to be susceptible to an extra recombination mechanism to which the other mutants were much less susceptible. The following observations were interpreted as evidence for the mismatch-repair