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Akademický článek

Antigen-binding fragments with improved crystal lattice packing and enhanced conformational flexibility at the elbow region as crystallization chaperones.

Autor: Bruce HA; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Singer AU; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Blazer LL; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Luu K; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Ploder L; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Pavlenco A; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Kurinov I; NE-CAT, Cornell University, Argonne, Illinois, USA., Adams JJ; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada., Sidhu SS; School of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada.

Publikováno v: Protein science : a publication of the Protein Society [Protein Sci] 2024 Jul; Vol. 33 (7), pp. e5081.

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Akademický článek

Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.

Autor: Miersch S; The Donnelly Centre, University of Toronto, Toronto, Canada., Li Z; Department of Molecular Genetics, University of Toronto, Toronto, Canada., Saberianfar R; The Donnelly Centre, University of Toronto, Toronto, Canada., Ustav M; Icosagen, Ōssu, Estonia., Brett Case J; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Blazer L; The Donnelly Centre, University of Toronto, Toronto, Canada., Chen C; The Donnelly Centre, University of Toronto, Toronto, Canada., Ye W; The Donnelly Centre, University of Toronto, Toronto, Canada., Pavlenco A; The Donnelly Centre, University of Toronto, Toronto, Canada., Gorelik M; The Donnelly Centre, University of Toronto, Toronto, Canada., Garcia Perez J; The Donnelly Centre, University of Toronto, Toronto, Canada., Subramania S; The Donnelly Centre, University of Toronto, Toronto, Canada., Singh S; The Donnelly Centre, University of Toronto, Toronto, Canada., Ploder L; The Donnelly Centre, University of Toronto, Toronto, Canada., Ganaie S; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Chen RE; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Leung DW; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Pandolfi PP; Renown Institute for Cancer, Nevada System of Higher Education, Reno, NV, USA; Department of Molecular Biotechnologies & Health Sciences, Molecular Biotechnology Center, University of Turin, Italy., Novelli G; Department of Biomedicine and Prevention, Tor Vergata University of Rome, 00133 Rome, Italy., Matusali G; Laboratory of Virology, National Institute for Infectious Diseases 'L. Spallanzani' IRCCS, Rome, Italy., Colavita F; Laboratory of Virology, National Institute for Infectious Diseases 'L. Spallanzani' IRCCS, Rome, Italy., Capobianchi MR; Laboratory of Virology, National Institute for Infectious Diseases 'L. Spallanzani' IRCCS, Rome, Italy., Jain S; Virna Therapeutics, West Roxbury, MA, USA., Gupta JB; Virna Therapeutics, West Roxbury, MA, USA., Amarasinghe GK; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Diamond MS; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA., Rini J; Department of Molecular Genetics, University of Toronto, Toronto, Canada; Department of Biochemistry, University of Toronto, Toronto, Canada. Electronic address: james.rini@utoronto.ca., Sidhu SS; The Donnelly Centre, University of Toronto, Toronto, Canada. Electronic address: sachdev.sidhu@utoronto.ca.

Publikováno v: Journal of molecular biology [J Mol Biol] 2021 Sep 17; Vol. 433 (19), pp. 167177. Date of Electronic Publication: 2021 Jul 28.

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Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.

Autor: Miersch S, Li Z, Saberianfar R, Ustav M, Case JB, Blazer L, Chen C, Ye W, Pavlenco A, Gorelik M, Perez JG, Subramania S, Singh S, Ploder L, Ganaie S, Chen RE, Leung DW, Pandolfi PP, Novelli G, Matusali G, Colavita F, Capobianchi MR, Jain S, Gupta JB, Amarasinghe GK, Diamond MS, Rini J, Sidhu SS

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2020 Dec 21. Date of Electronic Publication: 2020 Dec 21.

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Akademický článek

The Formation and Renewal of Photoreceptor Outer Segments.

Autor: Xu, Jingjin^1,2 (AUTHOR) 13969737352@163.com, Zhao, Chengtian^1,2 (AUTHOR) chengtian_zhao@ouc.edu.cn, Kang, Yunsi^1,2 (AUTHOR) kangyunsi@ouc.edu.cn

Publikováno v: Cells (2073-4409). Aug2024, Vol. 13 Issue 16, p1357. 17p.

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Akademický článek

In situ antibody phage display yields optimal inhibitors of integrin α11/β1.

Autor: Gallo E; Department of Molecular Genetics, University of Toronto, Donnelly Centre, Toronto, Ontario, Canada., Kelil A; Department of Molecular Genetics, University of Toronto, Donnelly Centre, Toronto, Ontario, Canada., Bayliss PE; Northern Biologics, Inc., Princess Margaret Cancer Research Tower, Toronto, Ontario, Canada., Jeganathan A; Northern Biologics, Inc., Princess Margaret Cancer Research Tower, Toronto, Ontario, Canada., Egorova O; Northern Biologics, Inc., Princess Margaret Cancer Research Tower, Toronto, Ontario, Canada., Ploder L; Department of Molecular Genetics, University of Toronto, Donnelly Centre, Toronto, Ontario, Canada., Adams JA; Department of Molecular Genetics, University of Toronto, Donnelly Centre, Toronto, Ontario, Canada., Giblin P; Northern Biologics, Inc., Princess Margaret Cancer Research Tower, Toronto, Ontario, Canada., Sidhu SS; Department of Molecular Genetics, University of Toronto, Donnelly Centre, Toronto, Ontario, Canada.

Publikováno v: MAbs [MAbs] 2020 Jan-Dec; Vol. 12 (1), pp. 1717265.

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The role of CHX10 in eye development: human CHX10 mutations in microphthalmia and identification of Mitf as a CHX10 downstream target

Autor: Cox, D, Duncan, A, PERÇİN, FERDA EMRİYE, Traboulsi, E, Yu, J, Horsford, DJ, Ploder, L, McInnes, L, Sarfarazi, M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10046::39d5812ba91174a0762115e5478b60cc
https://avesis.gazi.edu.tr/publication/details/f85850ad-0b04-44c6-9488-edab5efd44ac/oai

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Akademický článek

Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.

Autor: Pollock SB; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94143., Hu A; Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada., Mou Y; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94143., Martinko AJ; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94143., Julien O; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94143., Hornsby M; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94143., Ploder L; Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada., Adams JJ; Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada., Geng H; Department of Laboratory Medicine, University of California, San Francisco, CA 94143., Müschen M; Department of Laboratory Medicine, University of California, San Francisco, CA 94143., Sidhu SS; Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada., Moffat J; Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada., Wells JA; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94143; jim.wells@ucsf.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Mar 13; Vol. 115 (11), pp. 2836-2841. Date of Electronic Publication: 2018 Feb 23.

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Akademický článek

Identification and Characterization of ATOH7-Regulated Target Genes and Pathways in Human Neuroretinal Development.

Autor: Atac, David¹ (AUTHOR) grubichatac@medmolgen.uzh.ch, Maggi, Kevin¹ (AUTHOR) kmaggi@medmolgen.uzh.ch, Feil, Silke¹ (AUTHOR) feil@medmolgen.uzh.ch, Maggi, Jordi¹ (AUTHOR) maggi@medmolgen.uzh.ch, Cuevas, Elisa² (AUTHOR) j.sowden@ucl.ac.uk, Sowden, Jane C.² (AUTHOR), Koller, Samuel¹ (AUTHOR) koller@medmolgen.uzh.ch, Berger, Wolfgang^1,3,4 (AUTHOR) berger@medmolgen.uzh.ch

Publikováno v: Cells (2073-4409). Jul2024, Vol. 13 Issue 13, p1142. 33p.

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