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Semi-Automated Protein Binding Methodology Using Equilibrium Dialysis and A Novel Mixed-Matrix Cassette Approach

Autor: Plise, Emile G., Tran, Daniel, Salphati, Laurent ^*

Publikováno v: In Journal of Pharmaceutical Sciences December 2010 99(12):5070-5078

Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma

Autor: Bronner, Sarah M., Merrick, Karl A., Murray, Jeremy, Salphati, Laurent, Moffat, John G., Pang, Jodie, Sneeringer, Christopher J., Dompe, Nicholas, Cyr, Patrick, Purkey, Hans, Boenig, Gladys de Leon, Li, Jun, Kolesnikov, Aleksandr, Larouche-Gauthier, Robin, Lai, Kwong Wah, Shen, Xiaoli, Aubert-Nicol, Samuel, Chen, Yi-Chen, Cheong, Jonathan, Crawford, James J., Hafner, Marc, Haghshenas, Pouyan, Jakalian, Araz, Leclerc, Jean-Philippe, Lim, Ngiap-Kie, O'Brien, Tom, Plise, Emile G., Shalan, Hadil, Sturino, Claudio, Wai, John, Xiao, Yang, Yin, Jianping, Zhao, Liang, Gould, Stephen, Olivero, Alan, Heffron, Timothy P.

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 15 August 2019 29(16):2294-2301

Preclinical Assessment of the PI3Kα Selective Inhibitor Inavolisib and Prediction of Its Pharmacokinetics and Efficacious Dose in Human.

Autor: Salphati, Laurent¹ (AUTHOR) salphati.laurent@gene.com, Pang, Jodie¹ (AUTHOR), Plise, Emile G.¹ (AUTHOR), Cheong, Jonathan¹ (AUTHOR), Braun, Marie-Gabrielle¹ (AUTHOR), Friedman, Lori S.¹ (AUTHOR), Hong Thibodeau, Rebecca¹ (AUTHOR), Jaochico, Allan¹ (AUTHOR), Johnson, Ryan¹ (AUTHOR), Liu, Ning¹ (AUTHOR), Nannini, Michelle¹ (AUTHOR), Sampath, Deepak¹ (AUTHOR), Song, Kyung¹ (AUTHOR), Hannan, Emily J.¹ (AUTHOR), Staben, Steven T.¹ (AUTHOR)

Publikováno v: Xenobiotica. Oct2024, p1-20. 20p. 7 Illustrations.

Understanding the Effect of Hydroxypropyl‐β‐Cyclodextrin on Fenebrutinib Absorption in an Itraconazole–Fenebrutinib Drug–Drug Interaction Study.

Autor: Durk, Matthew R., Jones, Nicholas S., Liu, Jia, Nagapudi, Karthik, Mao, Chen, Plise, Emile G., Wong, Susan, Chen, Jacob Z., Chen, Yuan, Chinn, Leslie W., Chiang, Po‐Chang

Publikováno v: Clinical Pharmacology & Therapeutics; Dec2020, Vol. 108 Issue 6, p1224-1232, 9p