Stress responsive miR-31 is a major modulator of mouse intestinal stem cells during regeneration and tumorigenesis

Autor: Tian, Y, Ma, X, Lv, C, Sheng, X, Song, Y, Andl, T, Plikus, MV, Sun, J, Ren, F, Shuai, J, Lengner, CJ, Cui, W, Yu, Z

Intestinal regeneration and tumorigenesis are believed to be driven by intestinal stem cells (ISCs). Elucidating mechanisms underlying ISC activation during regeneration and tumorigenesis can help uncover the underlying principles of intestinal homeo

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http://hdl.handle.net/10044/1/50663

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Dermal TRPV1 innervations engage a macrophage- and fibroblast-containing pathway to activate hair growth in mice.

Autor: Ben-Shaanan TL; Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: tamar.ben-shaanan@ucsf.edu., Knöpper K; Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA., Duan L; Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA., Liu R; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA., Taglinao H; Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA., Xu Y; Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA., An J; Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA., Plikus MV; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA., Cyster JG; Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: jason.cyster@ucsf.edu.

Publikováno v: Developmental cell [Dev Cell] 2024 Nov 04; Vol. 59 (21), pp. 2818-2833.e7. Date of Electronic Publication: 2024 Jun 07.

Ancestral Diversity of Skin Reaches Single-Cell Resolution.

Autor: Liu Y; Department of Developmental and Cell Biology, Charlie Dunlop School of Biological Sciences, University of California, Irvine, Irvine, California, USA; Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, California, USA., Andersen B; Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, California, USA; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, California, USA; Center for Complex Biological Systems, University of California, Irvine, Irvine, California, USA; Department of Biological Chemistry, School of Medicine, University of California, Irvine, Irvine, California, USA; Division of Endocrinology, Department of Medicine, School of Medicine, University of California, Irvine, Irvine, California, USA., Gudjonsson JE; Department of Dermatology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA; Mary H. Weiser Food Allergy Center, University of Michigan, Ann Arbor, Michigan, USA., Plikus MV; Department of Developmental and Cell Biology, Charlie Dunlop School of Biological Sciences, University of California, Irvine, Irvine, California, USA; Sue & Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, California, USA; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, California, USA; Center for Complex Biological Systems, University of California, Irvine, Irvine, California, USA. Electronic address: plikus@uci.edu.

Publikováno v: The Journal of investigative dermatology [J Invest Dermatol] 2024 Sep 20. Date of Electronic Publication: 2024 Sep 20.

Hydrogel crosslinking modulates macrophages, fibroblasts, and their communication, during wound healing.

Autor: Butenko S; Department of Biomedical Engineering, University of California Irvine, Irvine, CA, USA.; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA., Nagalla RR; Department of Biomedical Engineering, University of California Irvine, Irvine, CA, USA., Guerrero-Juarez CF; Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana-Champaign, IL, USA., Palomba F; Department of Biomedical Engineering, University of California Irvine, Irvine, CA, USA., David LM; Department of Biomedical Engineering, University of California Irvine, Irvine, CA, USA., Nguyen RQ; Department of Biomedical Engineering, University of California Irvine, Irvine, CA, USA., Gay D; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA., Almet AA; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, USA.; Department of Mathematics, University of California, Irvine, Irvine, CA, USA., Digman MA; Department of Biomedical Engineering, University of California Irvine, Irvine, CA, USA.; Laboratory of Fluorescence Dynamics, The Henry Samueli School of Engineering, University of California, Irvine, CA, USA., Nie Q; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, USA.; Department of Mathematics, University of California, Irvine, Irvine, CA, USA.; Center for Complex Biological Systems, University of California Irvine, Irvine, CA, USA., Scumpia PO; Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Dermatology, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, CA, USA., Plikus MV; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA.; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA, USA., Liu WF; Department of Biomedical Engineering, University of California Irvine, Irvine, CA, USA. wendy.liu@uci.edu.; UCI Edwards Lifesciences Foundation Cardiovascular Innovation and Research Center, University of California Irvine, Irvine, CA, USA. wendy.liu@uci.edu.; Institute for Immunology, University of California, Irvine, Irvine, CA, USA. wendy.liu@uci.edu.; Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, USA. wendy.liu@uci.edu.; Department of Chemical and Biomolecular Engineering, University of California Irvine, Irvine, CA, USA. wendy.liu@uci.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Aug 09; Vol. 15 (1), pp. 6820. Date of Electronic Publication: 2024 Aug 09.