Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Pleuni Ooijevaar-De Heer"'
Autor:
Gertjan Wolbink, Theo Rispens, Dirkjan van Schaardenburg, Laurette van Boheemen, Pleuni Ooijevaar-De Heer, Nienke Oskam, Dorien Kos
Publikováno v:
RMD Open, Vol 10, Iss 3 (2024)
Objective Rheumatoid arthritis (RA) is characterised by the presence of autoantibodies, among which those targeting the constant region of immunoglobulin G (IgG), called rheumatoid factors (RF). Despite this link, RFs can also be found in other disor
Externí odkaz:
https://doaj.org/article/0469c3bfd95e490c922bfa1ff92e55f1
Autor:
Sofie Keijzer, Nienke Oskam, Pleuni Ooijevaar-de Heer, Maurice Steenhuis, Jim B.D. Keijser, Luuk Wieske, Koos P.J. van Dam, Eileen W. Stalman, Laura Y.L. Kummer, Laura Boekel, Taco W. Kuijpers, Anja ten Brinke, S. Marieke van Ham, Filip Eftimov, Sander W. Tas, Gerrit J. Wolbink, Theo Rispens
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundRheumatoid factors (RFs) are autoantibodies that target the Fc region of IgG, and are found in patients with rheumatic diseases as well as in the healthy population. Many studies suggest that an immune trigger may (transiently) elicit RF re
Externí odkaz:
https://doaj.org/article/f23a6c0fb19b45e796cbf67b6dbbd340
Autor:
Maximilian Brinkhaus, Elvera J. van der Kooi, Arthur E. H. Bentlage, Pleuni Ooijevaar-de Heer, Ninotska I. L. Derksen, Theo Rispens, Gestur Vidarsson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract The neonatal Fc receptor (FcRn) is known to mediate placental transfer of IgG from mother to unborn. IgE is widely known for triggering immune responses to environmental antigens. Recent evidence suggests FcRn-mediated transplacental passage
Externí odkaz:
https://doaj.org/article/5fdd3abbf8cf45a8a0f84e8b0d8bc3c5
Autor:
Nienke Oskam, Timon Damelang, Marij Streutker, Pleuni Ooijevaar-de Heer, Jan Nouta, Carolien Koeleman, Julie Van Coillie, Manfred Wuhrer, Gestur Vidarsson, Theo Rispens
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Of the four human immunoglobulin G (IgG) subclasses, IgG4 is considered the least inflammatory, in part because it poorly activates the complement system. Regardless, in IgG4 related disease (IgG4-RD) and in autoimmune disorders with high levels of I
Externí odkaz:
https://doaj.org/article/fa7318757d8145ef9a4785fb09b3e46d
Autor:
Sanne Reijm, Theresa Kissel, Gerrie Stoeken-Rijsbergen, Linda M. Slot, Corrie M. Wortel, Hugo J. van Dooren, Nivine E. W. Levarht, Arieke S. B. Kampstra, Veerle F. A. M. Derksen, Pleuni Ooijevaar-de Heer, Holger Bang, Jan W. Drijfhout, Leendert A. Trouw, Tom W. J. Huizinga, Theo Rispens, Hans U. Scherer, René E. M. Toes
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background Anti-modified protein antibodies (AMPA) targeting citrullinated, acetylated and/or carbamylated self-antigens are hallmarks of rheumatoid arthritis (RA). Although AMPA-IgG cross-reactivity to multiple post-translational modificati
Externí odkaz:
https://doaj.org/article/63a2b8cb09d24e27bf69a399f673442e
Autor:
Maurice Steenhuis, Gerard vanMierlo, Ninotska IL Derksen, Pleuni Ooijevaar‐de Heer, Simone Kruithof, Floris L Loeff, Lea C Berkhout, Federica Linty, Chantal Reusken, Johan Reimerink, Boris Hogema, Hans Zaaijer, Leo van deWatering, Francis Swaneveld, Marit J vanGils, Berend Jan Bosch, S Marieke vanHam, Anja tenBrinke, Gestur Vidarsson, Ellen C van derSchoot, Theo Rispens
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 5, Pp n/a-n/a (2021)
Abstract Objectives Characterisation of the human antibody response to SARS‐CoV‐2 infection is vital for serosurveillance purposes and for treatment options such as transfusion with convalescent plasma or immunoglobulin products derived from conv
Externí odkaz:
https://doaj.org/article/90bc47650aa74ada89a585d8baee315c
Autor:
Fleur S. van de Bovenkamp, Ninotska I. L. Derksen, Mariëlle J. van Breemen, Steven W. de Taeye, Pleuni Ooijevaar-de Heer, Rogier W. Sanders, Theo Rispens
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Immunoglobulin G (IgG) can contain N-linked glycans in the variable domains, the so-called Fab glycans, in addition to the Fc glycans in the CH2 domains. These Fab glycans are acquired following introduction of N-glycosylation sites during somatic hy
Externí odkaz:
https://doaj.org/article/0055da8dc52145e294c840fdd3f67479
Autor:
Anna E. van Beek, Richard B. Pouw, Mieke C. Brouwer, Gerard van Mierlo, Judy Geissler, Pleuni Ooijevaar-de Heer, Martin de Boer, Karin van Leeuwen, Theo Rispens, Diana Wouters, Taco W. Kuijpers
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The complement factor H-related (FHR) proteins are hypothesized to fine-tune the regulatory role of complement factor H (FH) in the alternative pathway of the complement system. Moreover, FHR-1, FHR-2, and FHR-5 have been proposed to be dimers, which
Externí odkaz:
https://doaj.org/article/fb471257e25b469cb0328c252b127083
Autor:
Nienke Oskam, Maurits A. den Boer, Marie V. Lukassen, Pleuni Ooijevaar-de Heer, Tim S. Veth, Gerard van Mierlo, Szu-Hsueh Lai, Ninotska I.L. Derksen, Victor C. Yin, Marij Streutker, Vojtech Franc, Marta Siborova, Mirjam Damen, Dorien Kos, Arjan Barendregt, Albert Bondt, Johannes B. van Goudoever, Carla J.C. Haas, Piet C. Aerts, Remy M. Muts, Suzan H.M. Rooijakkers, Gestur Vidarsson, Theo Rispens, Albert J.R. Heck
Immunoglobulin M (IgM) is an evolutionary conserved key component of humoral immunity, and the first antibody isotype to emerge during an immune response. IgM is a large (1 MDa), multimeric protein, for which both hexameric and pentameric structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfe919ea25200c16cec804bd3089d378
https://doi.org/10.1101/2023.05.27.542462
https://doi.org/10.1101/2023.05.27.542462
Autor:
Nienke Oskam, Pleuni Ooijevaar-De Heer, Dorien Kos, Jorn Jeremiasse, Laurette van Boheemen, Gwenny M Verstappen, Frans G M Kroese, Dirkjan van Schaardenburg, Gertjan Wolbink, Theo Rispens
Publikováno v:
Annals of the Rheumatic Diseases. BMJ Publishing Group
Oskam, N, Ooijevaar-de Heer, P, Kos, D, Jeremiasse, J, van Boheemen, L, Verstappen, G M, Kroese, F G M, van Schaardenburg, D, Wolbink, G & Rispens, T 2023, ' Rheumatoid factor autoantibody repertoire profiling reveals distinct binding epitopes in health and autoimmunity ', Annals of the Rheumatic Diseases, vol. 82, no. 7, 223901, pp. 945-956 . https://doi.org/10.1136/ard-2023-223901
Annals of the rheumatic diseases. BMJ Publishing Group
Oskam, N, Ooijevaar-de Heer, P, Kos, D, Jeremiasse, J, van Boheemen, L, Verstappen, G M, Kroese, F G M, van Schaardenburg, D, Wolbink, G & Rispens, T 2023, ' Rheumatoid factor autoantibody repertoire profiling reveals distinct binding epitopes in health and autoimmunity ', Annals of the Rheumatic Diseases, vol. 82, no. 7, 223901, pp. 945-956 . https://doi.org/10.1136/ard-2023-223901
Annals of the rheumatic diseases. BMJ Publishing Group
BackgroundRheumatoid factors (RF) are one of the hallmark autoantibodies characteristic of rheumatoid arthritis (RA), and are frequently observed in other diseases and in healthy individuals. RFs comprise multiple subtypes with different specificitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113306aad0942060cc08d4ee9ab4034d
https://doi.org/10.1136/ard-2023-223901
https://doi.org/10.1136/ard-2023-223901