Cross-platform DNA motif discovery and benchmarking to explore binding specificities of poorly studied human transcription factors.

Autor: Vorontsov IE; Vavilov Institute of General Genetics, Russian Academy of Sciences, 119991, Moscow, Russia.; Life Improvement by Future Technologies (LIFT) Center, 121205, Moscow, Russia., Kozin I; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119991, Moscow, Russia., Abramov S; Vavilov Institute of General Genetics, Russian Academy of Sciences, 119991, Moscow, Russia.; Altius Institute for Biomedical Sciences, 98121, Seattle, WA, USA., Boytsov A; Vavilov Institute of General Genetics, Russian Academy of Sciences, 119991, Moscow, Russia.; Altius Institute for Biomedical Sciences, 98121, Seattle, WA, USA., Jolma A; Donnelly Centre and Department of Molecular Genetics, Toronto, ON M5S 3E1, Canada., Albu M; Donnelly Centre and Department of Molecular Genetics, Toronto, ON M5S 3E1, Canada., Ambrosini G; École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland., Faltejskova K; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 160 00 Praha 6, Czech Republic.; Computer Science Institute, Faculty of Mathematics and Physics, Charles University, 118 00 Praha 1, Czech Republic., Gralak AJ; Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland., Gryzunov N; Life Improvement by Future Technologies (LIFT) Center, 121205, Moscow, Russia.; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119991, Moscow, Russia., Inukai S; Chugai Pharmaceutical Co., Ltd, Tokyo, 103-8324, Japan., Kolmykov S; Department of Computational Biology, Sirius University of Science and Technology, 354340, Sirius, Krasnodar region, Russia., Kravchenko P; Max Planck Institute of Biochemistry, 82152, Planegg, Germany., Kribelbauer-Swietek JF; Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland., Laverty KU; Donnelly Centre and Department of Molecular Genetics, Toronto, ON M5S 3E1, Canada., Nozdrin V; Life Improvement by Future Technologies (LIFT) Center, 121205, Moscow, Russia.; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119991, Moscow, Russia., Patel ZM; Donnelly Centre and Department of Molecular Genetics, Toronto, ON M5S 3E1, Canada., Penzar D; Vavilov Institute of General Genetics, Russian Academy of Sciences, 119991, Moscow, Russia., Plescher ML; Institute of Computer Science, Martin Luther University Halle-Wittenberg, 06099, Halle, Germany., Pour SE; Donnelly Centre and Department of Molecular Genetics, Toronto, ON M5S 3E1, Canada., Razavi R; Donnelly Centre and Department of Molecular Genetics, Toronto, ON M5S 3E1, Canada., Yang AWH; Donnelly Centre and Department of Molecular Genetics, Toronto, ON M5S 3E1, Canada., Yevshin I; Biosoft.Ru LLC, 630058, Novosibirsk, Russia., Zinkevich A; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119991, Moscow, Russia., Weirauch MT; Cincinnati Children's Hospital, Cincinnati, OH 45229, USA., Bucher P; Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland., Deplancke B; Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland., Fornes O; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, University of British Columbia, Vancouver, BC V5Z 4H4, Canada., Grau J; Institute of Computer Science, Martin Luther University Halle-Wittenberg, 06099, Halle, Germany., Grosse I; Institute of Computer Science, Martin Luther University Halle-Wittenberg, 06099, Halle, Germany., Kolpakov FA; Department of Computational Biology, Sirius University of Science and Technology, 354340, Sirius, Krasnodar region, Russia.; Bioinformatics Laboratory, Federal Research Center for Information and Computational Technologies, 630090, Novosibirsk, Russia., Makeev VJ; Vavilov Institute of General Genetics, Russian Academy of Sciences, 119991, Moscow, Russia.; Moscow Center for Advanced Studies, 123592, Moscow, Russia., Hughes TR; Donnelly Centre and Department of Molecular Genetics, Toronto, ON M5S 3E1, Canada., Kulakovskiy IV; Vavilov Institute of General Genetics, Russian Academy of Sciences, 119991, Moscow, Russia.; Life Improvement by Future Technologies (LIFT) Center, 121205, Moscow, Russia.; Institute of Protein Research, Russian Academy of Sciences, 142290, Pushchino, Russia.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 13. Date of Electronic Publication: 2024 Nov 13.