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Autor:
Plaza-Pegueroles, Adrián, Aphasizheva, Inna, Aphasizhev, Ruslan, Fernández-Tornero, Carlos, Ruiz, Federico M.
Publikováno v:
In Structure 11 July 2024 32(7):930-940
Autor:
Phong Quoc Nguyen, Sonia Huecas, Amna Asif-Laidin, Adrián Plaza-Pegueroles, Beatrice Capuzzi, Noé Palmic, Christine Conesa, Joël Acker, Juan Reguera, Pascale Lesage, Carlos Fernández-Tornero
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Cryo-EM structures of Ty1 integrase-Pol III complexes reveal determinants of Ty1 targeting upstream of Pol III-transcribed genes, and a functional impact of the integrase on Pol III activity that may increase the probability of Ty1 integration.
Externí odkaz:
https://doaj.org/article/ae5e1040373b42eb93f7571525af5479
Akademický článek
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Autor:
Sanz-Murillo, Marta, Plaza-Pegueroles, Adrián, Huecas, Sonia, Nguyen, Phong, Ruiz, Federico M., Fernández-Tornero, Carlos
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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RNA polymerases are central to transcription as they catalyze RNA synthesis using DNA as template. Malfunction of these cellular machines is related to a number of diseases including cancer. Eukaryotes require three different RNA polymerase
RNA polymerases are central to transcription as they catalyze RNA synthesis using DNA as template. Malfunction of these cellular machines is related to a number of diseases including cancer. Eukaryotes require three different RNA polymerase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::607a31ffa797eff6819d103faeb34238
http://hdl.handle.net/10261/268621
http://hdl.handle.net/10261/268621
Autor:
Phong Quoc Nguyen, Sonia Huecas, Amna Asif-Laidin, Adrián Plaza-Pegueroles, Noé Palmic, Joël Acker, Juan Reguera, Pascale Lesage, Carlos Fernández-Tornero
SummaryThe yeast Ty1 retrotransposon integrates upstream of genes transcribed by RNA polymerase III (Pol III). Specificity of integration is mediated by an interaction between the Ty1 integrase (IN1) and Pol III, currently uncharacterized at the atom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7497fda6a62427370447da274cd2e646
https://doi.org/10.1101/2022.03.07.483246
https://doi.org/10.1101/2022.03.07.483246