Breast Tumor Kinase (Brk/PTK6) Mediates Advanced Cancer Phenotypes via SH2-Domain Dependent Activation of RhoA and Aryl Hydrocarbon Receptor (AhR) Signaling.

Autor: Dwyer AR; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Kerkvliet CP; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Krutilina RI; Department of Pathology and Laboratory Medicine and Center for Cancer Research, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee., Playa HC; Department of Pathology and Laboratory Medicine and Center for Cancer Research, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee., Parke DN; Department of Pathology and Laboratory Medicine and Center for Cancer Research, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee., Thomas WA; Department of Pathology and Laboratory Medicine and Center for Cancer Research, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee., Smeester BA; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Moriarity BS; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Seagroves TN; Department of Pathology and Laboratory Medicine and Center for Cancer Research, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee. lange047@umn.edu tseagro1@uthsc.edu., Lange CA; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota. lange047@umn.edu tseagro1@uthsc.edu.; Departments of Medicine (Division of Hematology, Oncology, and Transplantation) and Pharmacology, University of Minnesota, Minneapolis, Minnesota.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2021 Feb; Vol. 19 (2), pp. 329-345. Date of Electronic Publication: 2020 Nov 10.

Simultaneous Multi-Organ Metastases from Chemo-Resistant Triple-Negative Breast Cancer Are Prevented by Interfering with WNT-Signaling.

Autor: Fatima I; Department of Medicine, College of Medicine at UTHSC (University of Tennessee Health Science Center), UTHSC Center for Cancer Research Memphis, Memphis, TN 38163, USA., El-Ayachi I; Department of Medicine, College of Medicine at UTHSC (University of Tennessee Health Science Center), UTHSC Center for Cancer Research Memphis, Memphis, TN 38163, USA., Playa HC; Department of Pathology and Laboratory Medicine, College of Medicine at UTHSC, UTHSC Center for Cancer Research, Memphis, TN 38163, USA., Alva-Ornelas JA; Department of Population Science, City of Hope Comprehensive Cancer Center and Beckman Institute, Duarte, CA 91010, USA., Khalid AB; Department of Orthopaedic Surgery and Biomedical Engineering, UTHSC Center for Cancer Research, UTHSC, Memphis, TN 38163, USA., Kuenzinger WL; Department of Medicine, College of Medicine at UTHSC (University of Tennessee Health Science Center), UTHSC Center for Cancer Research Memphis, Memphis, TN 38163, USA., Wend P; Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095, USA., Pence JC; Department of Orthopaedic Surgery and Biomedical Engineering, UTHSC Center for Cancer Research, UTHSC, Memphis, TN 38163, USA., Brakefield L; Department of Medicine, College of Medicine at UTHSC (University of Tennessee Health Science Center), UTHSC Center for Cancer Research Memphis, Memphis, TN 38163, USA., Krutilina RI; Department of Pathology and Laboratory Medicine, College of Medicine at UTHSC, UTHSC Center for Cancer Research, Memphis, TN 38163, USA., Johnson DL; Molecular Bioinformatics Core, UTHSC, Memphis, TN 38163, USA., O'Regan RM; Departments of Medicine, Division of Hematology and Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA., Seewaldt V; Department of Population Science, City of Hope Comprehensive Cancer Center and Beckman Institute, Duarte, CA 91010, USA., Seagroves TN; Department of Pathology and Laboratory Medicine, College of Medicine at UTHSC, UTHSC Center for Cancer Research, Memphis, TN 38163, USA., Krum SA; Department of Orthopaedic Surgery and Biomedical Engineering, UTHSC Center for Cancer Research, UTHSC, Memphis, TN 38163, USA., Miranda-Carboni GA; Department of Medicine, College of Medicine at UTHSC (University of Tennessee Health Science Center), UTHSC Center for Cancer Research Memphis, Memphis, TN 38163, USA.

Publikováno v: Cancers [Cancers (Basel)] 2019 Dec 17; Vol. 11 (12). Date of Electronic Publication: 2019 Dec 17.