Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Platypus venom"'
Autor:
Katherine Belov, Marilyn B. Renfree, Welsey C Warren, Camilla M. Whittington, Katrina M. Morris, Sara Gombert, Ehtesham Mofiz, Anthony T. Papenfuss, Emily S. W. Wong, Glenn F. King, Peter Temple-Smith, David Morgenstern
Publikováno v:
Molecular & Cellular Proteomics. 11:1354-1364
The platypus is a venomous monotreme. Male platypuses possess a spur on their hind legs that is connected to glands in the pelvic region. They produce venom only during the breeding season, presumably to fight off conspecifics. We have taken advantag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2caa420db4df2ea493fdc14dcf5381bc
https://doi.org/10.1074/mcp.m112.017491
https://doi.org/10.1074/mcp.m112.017491
Autor:
Masaki Kita
Publikováno v:
Pure and applied chemistry. 84(6):1317-1328
Venomous mammals are rare, and only a few species in the orders Insectivora and Monotremata produce toxic venom. Among them, the duckbill platypus (Ornithorhynchus anatinus) is one of the two venomous Australian mammals. The adult male platypus carri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4362272431dc4640cbacb4314de48cd
https://tsukuba.repo.nii.ac.jp/records/27427
https://tsukuba.repo.nii.ac.jp/records/27427
Autor:
Camilla M. Whittington, Katherine Belov, Wesley C. Warren, Emily S. W. Wong, Anthony T. Papenfuss
Publikováno v:
Molecular Biology and Evolution. 29:167-177
Gene duplication followed by adaptive selection is believed to be the primary driver of venom evolution. However, to date, no studies have evaluated the importance of gene duplications for venom evolution using a genomic approach. The availability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f183eccfe4ed16553437e3a72f31385
https://doi.org/10.1093/molbev/msr180
https://doi.org/10.1093/molbev/msr180
Publikováno v:
Chemistry & Biodiversity. 7:1603-1611
Male platypus (Ornithorhynchus anatinus) venom has a peptidyl aminoacyl L/D-isomerase (hereafter called peptide isomerase) that converts the second amino acid residue in from the N-terminus from the L- to the D-form, and vice versa. A reversed-phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63da55f34d924a659dc380a535b8f53
https://doi.org/10.1002/cbdv.200900300
https://doi.org/10.1002/cbdv.200900300
Publikováno v:
Pure and Applied Chemistry. 81:1093-1111
The discovery of new ecologically active compounds often triggers the development of basic scientific concepts in the field of biological sciences, since such compounds have direct physiological and behavioral effects on other living organisms. We ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::420d512a26ee1d7a6696d7fe8ff36111
https://doi.org/10.1351/pac-con-08-08-12
https://doi.org/10.1351/pac-con-08-08-12
Autor:
Philip W. Kuchel, Allan M. Torres, Camilla M. Whittington, Wesley C. Warren, Katherine Belov, Anthony T. Papenfuss, Jennifer M. S. Koh
Publikováno v:
Journal of Proteomics. 72:155-164
Only five mammalian species are known to be venomous, and while a large amount of research has been carried out on reptile venom, mammalian venom has been poorly studied to date. Here we describe the status of current research into the venom of the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c7a9dff57eaf9b9d096e66031de708
https://doi.org/10.1016/j.jprot.2008.12.004
https://doi.org/10.1016/j.jprot.2008.12.004
Publikováno v:
Toxicon. 52:559-565
The platypus, as an egg-laying mammal, displays an unusual mixture of reptilian and mammalian characteristics. It is also venomous, and further investigations into its little-studied venom may lead to the development of novel pharmaceuticals and drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff050a84058922696ebc4c557e97096
https://doi.org/10.1016/j.toxicon.2008.07.002
https://doi.org/10.1016/j.toxicon.2008.07.002
Autor:
Philip W. Kuchel, Camilla M. Whittington, Janine E. Deakin, Peter Temple-Smith, Katherine Belov, Colin Kremitzki, Amber E. Alsop, Chris P. Ponting, Tina Graves, Allan M. Torres, Emily S. W. Wong, Kyriena Schatzkamer, Paramjit S. Bansal, Welsey C Warren, Anthony T. Papenfuss
Publikováno v:
Genome Research. 18:986-994
When the platypus (Ornithorhynchus anatinus) was first discovered, it was thought to be a taxidermist’s hoax, as it has a blend of mammalian and reptilian features. It is a most remarkable mammal, not only because it lays eggs but also because it i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6a462197c39d0c07b6087184aaf63c
https://doi.org/10.1101/gr.7149808
https://doi.org/10.1101/gr.7149808
Autor:
Paul F. Alewood, Alun Jones, David J. Adams, Simon T. Nevin, Annette Nicke, Christina I. Schroeder, Marion L. Loughnan, Richard J. Lewis
Publikováno v:
Journal of Biological Chemistry. 281:24745-24755
The venoms of predatory marine snails (Conus spp.) contain diverse mixtures of peptide toxins with high potency and selectivity for a variety of voltage-gated and ligand-gated ion channels. Here we describe the chemical and functional characterizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b483577d0be2d255f9bb5892bb4769df
https://doi.org/10.1074/jbc.m603703200
https://doi.org/10.1074/jbc.m603703200
Publikováno v:
Toxicon. 40:711-719
Nuclear magnetic resonance spectroscopy was used to investigate the conformations of the platypus venom C-type natriuretic peptide A (OvCNPa) in aqueous solutions and in solutions containing sodium dodecyl sulfate (SDS) micelles. The chemically synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce141550649a5db95741dd5ea72ac1d5
https://doi.org/10.1016/s0041-0101(01)00266-5
https://doi.org/10.1016/s0041-0101(01)00266-5