Zobrazeno 1 - 10
of 1 673
pro vyhledávání: '"Platt, Robert W."'
Autor:
Webster-Clark, Michael, Matthews, Anthony A., Ellis, Alan R., Kinlaw, Alan C., Platt, Robert W.
Subgroup analyses are common in epidemiologic and clinical research. Unfortunately, restriction to subgroup members to test for heterogeneity can yield imprecise effect estimates. If the true effect differs between members and non-members due to diff
Externí odkaz:
http://arxiv.org/abs/2406.08297
Clone-censor-weighting (CCW) is an analytic method for studying treatment regimens that are indistinguishable from one another at baseline without relying on landmark dates or creating immortal person time. One particularly interesting CCW applicatio
Externí odkaz:
http://arxiv.org/abs/2404.15073
Autor:
Jaman, Ajmery, Wang, Guanbo, Ertefaie, Ashkan, Bally, Michèle, Lévesque, Renée, Platt, Robert W., Schnitzer, Mireille E.
Effect modification occurs when the impact of the treatment on an outcome varies based on the levels of other covariates known as effect modifiers. Modeling of these effect differences is important for etiological goals and for purposes of optimizing
Externí odkaz:
http://arxiv.org/abs/2402.00154
Autor:
Chatton, Arthur, Bally, Michèle, Lévesque, Renée, Malenica, Ivana, Platt, Robert W., Schnitzer, Mireille E.
Obtaining continuously updated predictions is a major challenge for personalised medicine. Leveraging combinations of parametric regressions and machine learning approaches, the personalised online super learner (POSL) can achieve such dynamic and pe
Externí odkaz:
http://arxiv.org/abs/2310.08479
Autor:
Wang, Guanbo, Lian, Yi, Yang, Archer Y., Platt, Robert W., Wang, Rui, Perreault, Sylvie, Dorais, Marc, Schnitzer, Mireille E.
Cox models with time-dependent coefficients and covariates are widely used in survival analysis. In high-dimensional settings, sparse regularization techniques are employed for variable selection, but existing methods for time-dependent Cox models la
Externí odkaz:
http://arxiv.org/abs/2306.12528
Autor:
Wang, Guanbo, Costello, Melanie Poulin, Pang, Herbert, Zhu, Jiawen, Helms, Hans-Joachim, Reyes-Rivera, Irmarie, Platt, Robert W., Pang, Menglan, Koukounari, Artemis
Publikováno v:
Pharmaceutical Statistics (2023)
Phase Ib/II oncology trials, despite their small sample sizes, aim to provide information for optimal internal company decision-making concerning novel drug development. Hybrid controls (a combination of the current control arm and controls from one
Externí odkaz:
http://arxiv.org/abs/2209.05354
Autor:
Wang, Guanbo, Perreault, Sylvie, Platt, Robert W., Wang, Rui, Dorais, Marc, Schnitzer, Mireille E.
The construction of coherent prediction models holds great importance in medical research as such models enable health researchers to gain deeper insights into disease epidemiology and clinicians to identify patients at higher risk of adverse outcome
Externí odkaz:
http://arxiv.org/abs/2206.05337
Publikováno v:
Statistics in Medicine; 40(26): 5746-5764, Copyright@2021, Wiley
In the statistical literature, a number of methods have been proposed to ensure valid inference about marginal effects of variables on a longitudinal outcome in settings with irregular monitoring times. However, the potential biases due to covariate-
Externí odkaz:
http://arxiv.org/abs/2112.11517
Autor:
Douros, Antonios, Cui, Ying, Platt, Robert W., Filion, Kristian B., Sebastiani, Giada, Renoux, Christel
Publikováno v:
In Thrombosis Research May 2024 237:71-78
Publikováno v:
Transactions on Machine Learning Research (2024/01)
In variable selection, a selection rule that prescribes the permissible sets of selected variables (called a "selection dictionary") is desirable due to the inherent structural constraints among the candidate variables. Such selection rules can be co
Externí odkaz:
http://arxiv.org/abs/2110.01031