Výsledky vyhledávání

Akademický článek

De novo designed EBAI as a potential inhibitor of the viral protein BHRF1. Research in silico .

Autor: Zaremba AA; Zabolotny Institute of Microbiology and Virology of NASU, Kyiv, Ukraine., Zaremba PY; Zabolotny Institute of Microbiology and Virology of NASU, Kyiv, Ukraine., Platonov MO; Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2023 May; Vol. 41 (8), pp. 3680-3685. Date of Electronic Publication: 2022 Mar 22.

Zobrazit plný text záznamu

Akademický článek

Single-Walled Carbon Nanotubes Inhibit TRPC4-Mediated Muscarinic Cation Current in Mouse Ileal Myocytes.

Autor: Al Kury LT; College of Natural and Health Sciences, Zayed University, Abu Dhabi 144534, United Arab Emirates., Papandreou D; College of Natural and Health Sciences, Zayed University, Abu Dhabi 144534, United Arab Emirates., Hurmach VV; ESC 'Institute of Biology and Medicine', Taras Shevchenko National University of Kyiv, 64 Volodymyrska Str., 01601 Kyiv, Ukraine., Dryn DO; ESC 'Institute of Biology and Medicine', Taras Shevchenko National University of Kyiv, 64 Volodymyrska Str., 01601 Kyiv, Ukraine.; O.O. Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, 4 Bogomoletz Str., 01024 Kyiv, Ukraine.; Institute of Pharmacology and Toxicology, National Academy of Medical Sciences of Ukraine, 14 Anton Tsedik Str., 03057 Kyiv, Ukraine., Melnyk MI; ESC 'Institute of Biology and Medicine', Taras Shevchenko National University of Kyiv, 64 Volodymyrska Str., 01601 Kyiv, Ukraine.; O.O. Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, 4 Bogomoletz Str., 01024 Kyiv, Ukraine.; Institute of Pharmacology and Toxicology, National Academy of Medical Sciences of Ukraine, 14 Anton Tsedik Str., 03057 Kyiv, Ukraine., Platonov MO; Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 150 Zabolotnogo Str., 03143 Kyiv, Ukraine., Prylutskyy YI; ESC 'Institute of Biology and Medicine', Taras Shevchenko National University of Kyiv, 64 Volodymyrska Str., 01601 Kyiv, Ukraine., Ritter U; Institute of Chemistry and Biotechnology, Technical University of Ilmenau, 25 Weimarer Str., 98693 Ilmenau, Germany., Scharff P; Institute of Chemistry and Biotechnology, Technical University of Ilmenau, 25 Weimarer Str., 98693 Ilmenau, Germany., Zholos AV; ESC 'Institute of Biology and Medicine', Taras Shevchenko National University of Kyiv, 64 Volodymyrska Str., 01601 Kyiv, Ukraine.

Publikováno v: Nanomaterials (Basel, Switzerland) [Nanomaterials (Basel)] 2021 Dec 16; Vol. 11 (12). Date of Electronic Publication: 2021 Dec 16.

Zobrazit plný text záznamu

Akademický článek

C 60 fullerene against SARS-CoV-2 coronavirus: an in silico insight.

Autor: Hurmach VV; Taras Shevchenko National University of Kyiv, Kyiv, 01601, Ukraine., Platonov MO; Institute of Molecular Biology and Genetics of NASU, Kyiv, 03143, Ukraine., Prylutska SV; Taras Shevchenko National University of Kyiv, Kyiv, 01601, Ukraine.; National University of Life and Environmental Science of Ukraine, Kyiv, 03041, Ukraine., Scharff P; Institute of Chemistry and Biotechnology, Technical University of Ilmenau, 98693, Ilmenau, Germany., Prylutskyy YI; Taras Shevchenko National University of Kyiv, Kyiv, 01601, Ukraine., Ritter U; Institute of Chemistry and Biotechnology, Technical University of Ilmenau, 98693, Ilmenau, Germany. uwe.ritter@tu-ilmenau.de.

Publikováno v: Scientific reports [Sci Rep] 2021 Sep 07; Vol. 11 (1), pp. 17748. Date of Electronic Publication: 2021 Sep 07.

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling.

Autor: Kamdem N; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Robert-Rössle-Straße 10, 13125 Berlin, Germany.; Institut für Chemie und Biochemie, Freie Universität Berlin, Takustraße 3, 14195 Berlin, Germany., Roske Y; Max Delbrück Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany., Kovalskyy D; Enamine Ltd., Chervonotkatska Street 78, Kyiv 02094, Ukraine.; ChemBio Ctr, Taras Shevchenko National University of Kyiv, 62 Volodymyrska, Kyiv 01033, Ukraine., Platonov MO; Enamine Ltd., Chervonotkatska Street 78, Kyiv 02094, Ukraine.; ChemBio Ctr, Taras Shevchenko National University of Kyiv, 62 Volodymyrska, Kyiv 01033, Ukraine., Balinskyi O; Enamine Ltd., Chervonotkatska Street 78, Kyiv 02094, Ukraine.; ChemBio Ctr, Taras Shevchenko National University of Kyiv, 62 Volodymyrska, Kyiv 01033, Ukraine., Kreuchwig A; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Robert-Rössle-Straße 10, 13125 Berlin, Germany.; Institut für Chemie und Biochemie, Freie Universität Berlin, Takustraße 3, 14195 Berlin, Germany., Saupe J; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Robert-Rössle-Straße 10, 13125 Berlin, Germany.; Institut für Chemie und Biochemie, Freie Universität Berlin, Takustraße 3, 14195 Berlin, Germany., Fang L; Institut für Chemie und Biochemie, Freie Universität Berlin, Takustraße 3, 14195 Berlin, Germany.; Max Delbrück Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany., Diehl A; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Robert-Rössle-Straße 10, 13125 Berlin, Germany., Schmieder P; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Robert-Rössle-Straße 10, 13125 Berlin, Germany., Krause G; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Robert-Rössle-Straße 10, 13125 Berlin, Germany., Rademann J; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Robert-Rössle-Straße 10, 13125 Berlin, Germany.; Institut für Pharmazie, Freie Universität Berlin, Königin-Luise-Straße 2 + 4, 14195 Berlin, Germany., Heinemann U; Institut für Chemie und Biochemie, Freie Universität Berlin, Takustraße 3, 14195 Berlin, Germany.; Max Delbrück Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany., Birchmeier W; Max Delbrück Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany., Oschkinat H; Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Robert-Rössle-Straße 10, 13125 Berlin, Germany.; Institut für Chemie und Biochemie, Freie Universität Berlin, Takustraße 3, 14195 Berlin, Germany.

Publikováno v: Magnetic resonance (Gottingen, Germany) [Magn Reson (Gott)] 2021 Jun 02; Vol. 2 (1), pp. 355-374. Date of Electronic Publication: 2021 Jun 02 (Print Publication: 2021).

Zobrazit plný text záznamu

Akademický článek

Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction.

Autor: Strizhak AV; University Chemical Laboratory, University of Cambridge, Lensfield Road, CB2 1EW Cambridge, UK. Spring@ch.cam.ac.uk and Enamine Ltd, Vul. Chervonotkatska 78, 02094 Kyiv, Ukraine., Babii O; Institute of Biological Interfaces (IBG-2), Karlsruhe Institute of Technology (KIT), POB 3640, 76021 Karlsruhe, Germany. Anne.Ulrich@kit.edu., Afonin S; Institute of Biological Interfaces (IBG-2), Karlsruhe Institute of Technology (KIT), POB 3640, 76021 Karlsruhe, Germany. Anne.Ulrich@kit.edu., Bakanovich I; University Chemical Laboratory, University of Cambridge, Lensfield Road, CB2 1EW Cambridge, UK. Spring@ch.cam.ac.uk and Enamine Ltd, Vul. Chervonotkatska 78, 02094 Kyiv, Ukraine., Pantelejevs T; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, CB2 1GA Cambridge, UK., Xu W; University Chemical Laboratory, University of Cambridge, Lensfield Road, CB2 1EW Cambridge, UK. Spring@ch.cam.ac.uk., Fowler E; University Chemical Laboratory, University of Cambridge, Lensfield Road, CB2 1EW Cambridge, UK. Spring@ch.cam.ac.uk., Eapen R; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD Cambridge, UK., Sharma K; University Chemical Laboratory, University of Cambridge, Lensfield Road, CB2 1EW Cambridge, UK. Spring@ch.cam.ac.uk., Platonov MO; Enamine Ltd, Vul. Chervonotkatska 78, 02094 Kyiv, Ukraine., Hurmach VV; Enamine Ltd, Vul. Chervonotkatska 78, 02094 Kyiv, Ukraine and Taras Shevchenko National University of Kyiv, Vul. Volodymyrska 60, 01601 Kyiv, Ukraine., Itzhaki L; Department of Pharmacology, University of Cambridge, Tennis Court Road, CB2 1PD Cambridge, UK., Hyvönen M; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, CB2 1GA Cambridge, UK., Ulrich AS; Institute of Biological Interfaces (IBG-2), Karlsruhe Institute of Technology (KIT), POB 3640, 76021 Karlsruhe, Germany. Anne.Ulrich@kit.edu and Institute of Organic Chemistry (IOC), KIT, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany., Spring DR; University Chemical Laboratory, University of Cambridge, Lensfield Road, CB2 1EW Cambridge, UK. Spring@ch.cam.ac.uk., Komarov IV; Taras Shevchenko National University of Kyiv, Vul. Volodymyrska 60, 01601 Kyiv, Ukraine and Lumobiotics GmbH, Auer Str. 2, 76227, Karlsruhe, Germany. Igor.Komarov@lumobiotics.com.

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2020 Jul 22; Vol. 18 (28), pp. 5359-5369.

Zobrazit plný text záznamu

Akademický článek

Synthesis, biological evaluation, and modeling studies of 1,3-disubstituted cyclobutane-containing analogs of combretastatin A4.

Autor: Malashchuk A; Enamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.; Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyiv 01601, Ukraine., Chernykh AV; Enamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine., Hurmach VV; Enamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.; Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyiv 01601, Ukraine., Platonov MO; Enamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine., Onopchenko O; Bienta/Enamine Ltd. (www.bienta.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine., Zozulya S; Bienta/Enamine Ltd. (www.bienta.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine., Daniliuc CG; Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster, Corrensstrasse 40, 48149 Münster, Germany., Dobrydnev AV; Enamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.; Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyiv 01601, Ukraine., Kondratov IS; Enamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.; Institute of Bioorganic Chemistry & Petrochemistry, NAS of Ukraine, Murmanska Street 1, Kyiv 02660, Ukraine., Moroz YS; Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyiv 01601, Ukraine.; Chemspace, Ilukstes iela 38-5, Riga, LV-1082, Latvia., Grygorenko OO; Enamine Ltd. (www.enamine.net), Chervonotkatska Street 78, Kyiv 02094, Ukraine.; Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyiv 01601, Ukraine.

Publikováno v: Journal of molecular structure [J Mol Struct] 2020 Jun 15; Vol. 1210. Date of Electronic Publication: 2020 May 10.

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání