Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2-associated schwannomas reveals differences in efficacy and drug resistance development.

Autor: Fuse MA; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida, USA., Dinh CT; Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA., Vitte J; Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA and Jonsson Comprehensive Cancer Center, University of California at Los Angeles (UCLA), Los Angeles, California, USA., Kirkpatrick J; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany., Mindos T; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany., Plati SK; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida, USA., Young JI; Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida, USA., Huang J; Center for Childhood Cancer and Blood Diseases, Nationwide Children's Hospital.; Department of Pediatrics, The Ohio State University, Columbus, Ohio, USA., Carlstedt A; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany., Franco MC; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida, USA., Brnjos K; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida, USA., Nagamoto J; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida, USA., Petrilli AM; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida, USA., Copik AJ; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida, USA., Soulakova JN; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida, USA., Bracho O; Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA., Yan D; Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA., Mittal R; Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA., Shen R; Department of Pathology, The Ohio State University, Columbus, Ohio, USA., Telischi FF; Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA., Morrison H; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany., Giovannini M; Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA and Jonsson Comprehensive Cancer Center, University of California at Los Angeles (UCLA), Los Angeles, California, USA., Liu XZ; Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA.; Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida, USA., Chang LS; Center for Childhood Cancer and Blood Diseases, Nationwide Children's Hospital.; Department of Pediatrics, The Ohio State University, Columbus, Ohio, USA., Fernandez-Valle C; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida (UCF), Orlando, Florida, USA.

Publikováno v: Neuro-oncology [Neuro Oncol] 2019 Mar 18; Vol. 21 (4), pp. 486-497.

Chromosomal abnormalities and copy number variations in fetal left-sided congenital heart defects.

Autor: Jansen FA; Department of Obstetrics and Fetal Medicine, Leiden University Medical Center, Leiden, the Netherlands., Hoffer MJ; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands., van Velzen CL; Department of Obstetrics, VU University Medical Center, Amsterdam, the Netherlands., Plati SK; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands., Rijlaarsdam ME; Department of Pediatric Cardiology of the Willem Alexander Children's Hospital, Leiden University Medical Center, Leiden, the Netherlands., Clur SA; Department of Pediatric Cardiology of the Emma Children's Hospital, Academic Medical Center, Amsterdam, the Netherlands., Blom NA; Department of Pediatric Cardiology of the Willem Alexander Children's Hospital, Leiden University Medical Center, Leiden, the Netherlands.; Department of Pediatric Cardiology of the Emma Children's Hospital, Academic Medical Center, Amsterdam, the Netherlands., Pajkrt E; Department of Obstetrics, Academic Medical Center, Amsterdam, the Netherlands., Bhola SL; Department of Clinical Genetics, VU University Medical Center, Amsterdam, the Netherlands., Knegt AC; Department of Clinical Genetics, Academic Medical Center, Amsterdam, the Netherlands., de Boer MA; Department of Obstetrics, VU University Medical Center, Amsterdam, the Netherlands., Haak MC; Department of Obstetrics and Fetal Medicine, Leiden University Medical Center, Leiden, the Netherlands.

Publikováno v: Prenatal diagnosis [Prenat Diagn] 2016 Feb; Vol. 36 (2), pp. 177-85. Date of Electronic Publication: 2016 Feb 03.