Zobrazeno 1 - 10
of 2 298
pro vyhledávání: '"Platelet inhibition"'
Autor:
Maria J. Reimann, Daniel N. Faisst, Mads Knold, Kathryn M. Meurs, Joshua A. Stern, Signe E. Cremer, Jacob E. Møller, Ingrid Ljungvall, Jens Häggström, Lisbeth H. Olsen
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 6, Pp 2145-2156 (2023)
Abstract Background A variant in the canine phosphodiesterase (PDE) 5A gene (PDE5A:E90K) is associated with decreased concentrations of circulating cyclic guanosine monophosphate (cGMP) and response to PDE5 inhibitor treatment. Pimobendan is a PDE in
Externí odkaz:
https://doaj.org/article/cd502d1817ad4c5a967b5c356fee7e03
Autor:
Fei Gao, Shunnan Ge, Wenxing Cui, Jingya Zhao, Yang Yang, Wei Guo, Hao Bai, Bao Wang, Chen Yang, Shijie Mu, Liang Wang, Tianzhi Zhao, Yan Qu, Yaning Cai
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26854- (2024)
Background: Studies have been inconclusive on the risk for hemorrhage in patients with a history of aspirin use who underwent emergency external ventricular drainage (EVD)/intracranial pressure (ICP) probe placement. The aim of this study was to expl
Externí odkaz:
https://doaj.org/article/df1fb4b5f0134b1f9c857ac4eacac4c0
Autor:
Giuseppe Gargiulo, Plinio Cirillo, Luca Sperandeo, Imma Forzano, Domenico Simone Castiello, Domenico Florimonte, Fiorenzo Simonetti, Roberta Paolillo, Lina Manzi, Alessandra Spinelli, Carmen Anna Maria Spaccarotella, Raffaele Piccolo, Luigi Di Serafino, Anna Franzone, Piera Capranzano, Marco Valgimigli, Giovanni Esposito
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 50, Iss , Pp 101344- (2024)
Background: There are limited data to assess pharmacodynamic (PD) profiles of patients with STEMI undergoing primary percutaneous coronary intervention (PCI) and receiving cangrelor after pretreatment with ticagrelor. Methods: The PharmacOdynaMic eff
Externí odkaz:
https://doaj.org/article/165157f62580481a8b26660fa57779c6
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Panax quinquefolius saponin (PQS) was shown beneficial against platelet adhesion and for gastroprotection. This study aimed to investigate the integrated efficacy of PQS with dual antiplatelet therapy (DAPT) on platelet aggregatio
Externí odkaz:
https://doaj.org/article/bca46420e5fe4df2bbcb597400585d07
Autor:
Vance G. Nielsen
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6334 (2024)
Eastern Diamondback Rattlesnake (Crotalus adamanteus) envenomation is a medical emergency encountered in the Southeastern United States. The venom contains a snake venom thrombin-like enzyme (SVTLE) that is defibrinogenating, causing coagulopathy wit
Externí odkaz:
https://doaj.org/article/01dddb4e27b244ce9c92f5b71de7c6a6
Autor:
Wilbert L. Jones, Christopher R. Ramos, Anirban Banerjee, Ernest E. Moore, Kirk C. Hansen, Julia R. Coleman, Marguerite Kelher, Keith B. Neeves, Christopher C. Silliman, Jorge Di Paola, Brian Branchford
Publikováno v:
Platelets, Vol 33, Iss 8, Pp 1119-1131 (2022)
Apolipoprotein A-I (ApoA-I) is elevated in the plasma of a subgroup of trauma patients with systemic hyperfibrinolysis. We hypothesize that apoA-I inhibits platelet activation and clot formation. The effects of apoA-I on human platelet activation and
Externí odkaz:
https://doaj.org/article/431566e32a634e068a99c0c4b4495a3e
Autor:
Martina Aguiar Bucsai, Christian Idel, Barbara Wollenberg, Christine Mannhalter, Admar Verschoor
Publikováno v:
Platelets, Vol 33, Iss 8, Pp 1192-1198 (2022)
We aimed to investigate the effects of integrin αIIbβ3 inhibitor tirofiban on hallmarks of platelet activation, degranulation, and aggregation during its use to analyze activated but non-complexed platelets via flow cytometry. To do so, we used was
Externí odkaz:
https://doaj.org/article/67d154783c2d4217a594f18f8ee8fe79
Akademický článek
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Publikováno v:
Clinical Case Reports, Vol 11, Iss 3, Pp n/a-n/a (2023)
Abstract Patients with acute coronary syndrome (ACS), failed percutaneous coronary intervention (PCI) and with an indication for emergent coronary artery bypass graft surgery (CABG) are at an increased risk of perioperative bleeding. Integration of t
Externí odkaz:
https://doaj.org/article/7c20487d45874249a3bce4490881df45
Autor:
Georg Gelbenegger, Juergen Grafeneder, Gloria M. Gager, Jolanta M. Siller-Matula, Michael Schwameis, Bernd Jilma, Christian Schoergenhofer
Publikováno v:
Thrombosis Journal, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background High on-treatment platelet reactivity (HTPR) remains a major problem in the acute management of ST-elevation myocardial infarction (STEMI), leading to higher rates of stent thrombosis and mortality. We aimed to investigate a novel
Externí odkaz:
https://doaj.org/article/fa89bc04d7374f58ab4cab59347007d1