Zobrazeno 1 - 10
of 335
pro vyhledávání: '"Platelet degranulation"'
Autor:
Martina Aguiar Bucsai, Christian Idel, Barbara Wollenberg, Christine Mannhalter, Admar Verschoor
Publikováno v:
Platelets, Vol 33, Iss 8, Pp 1192-1198 (2022)
We aimed to investigate the effects of integrin αIIbβ3 inhibitor tirofiban on hallmarks of platelet activation, degranulation, and aggregation during its use to analyze activated but non-complexed platelets via flow cytometry. To do so, we used was
Externí odkaz:
https://doaj.org/article/67d154783c2d4217a594f18f8ee8fe79
Akademický článek
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Autor:
Abu Saleh Md Moin, Manjula Nandakumar, Thozhukat Sathyapalan, Stephen L. Atkin, Alexandra E. Butler
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-4 (2021)
Externí odkaz:
https://doaj.org/article/fdcde42d035649a78a66480aa8956895
Autor:
Yu He, Zhili Wang, Jianhua Wei, Zhongying Yang, Luo Ren, Yu Deng, Shiyi Chen, Na Zang, Enmei Liu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Respiratory syncytial virus (RSV) a leading cause of pediatric and adult morbidity and mortality worldwide. It can cause complications in multiple organs, thus increasing hospital stays and costs. However, RSV-based studies have primarily focused on
Externí odkaz:
https://doaj.org/article/927c38197b3546bdb3fdbba6e133341a
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Ischemic stroke is among the leading causes of disability and death worldwide. In acute ischemic stroke, the rapid recanalization of occluded cranial vessels is the primary therapeutic aim. However, experimental data (obtained using mostly the transi
Externí odkaz:
https://doaj.org/article/0990eb1706ce49e0abc3763105c2175e
Autor:
Avi Z. Rosenberg, H. Michael Belmont, Paride Fenaroli, Nir Hacohen, Arnon Arazi, William Apruzzese, Chandra Mohan, Accelerating Medicines Partnership Ra, Jose Monroy Trujillo, Jill Buyon, Robert R. Clancy, Michelle Petri, Deepak A. Rao, Derek M. Fine, Peter M. Izmirly, David Wofsy, Anne Davidson, Andrea Fava, Betty Diamond, Celine C. Berthier, Judith A. James, Soumya Raychaudhuri, Ting Zhang
Publikováno v:
Arthritis & Rheumatology. 74:829-839
Objectives Current treatments are effective only in 30% of lupus nephritis patients emphasizing the need for novel therapeutic strategies. To develop mechanistic hypotheses and explore novel biomarkers, we analyzed the longitudinal urinary proteomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9c2331ee5a6c2957b445daabc792409
https://doi.org/10.1002/art.42023
https://doi.org/10.1002/art.42023
Autor:
Kirsten Leineweber, Vincent ten Cate, Philipp S. Wild, Karl J. Lackner, Bianca Wagner, Stefan Heitmeier, Imke Meyer, Lisa Eggebrecht, Marina Panova-Noeva, Markus Nagler, Thomas Koeck, Jürgen H. Prochaska, Christoph Gerdes, Stavros Konstantinides, Hugo ten Cate, Henri M. H. Spronk
Publikováno v:
Journal of Thrombosis and Haemostasis, 20(3), 705-715. Wiley
Background The role of platelets in the pathogenesis of venous thromboembolism (VTE) is receiving increasing attention; however, limited information is available on platelet function in the acute phase of the disease. Objective To characterize platel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54b570b6214cb8b3d6a0c3be56ac7bb
https://doi.org/10.1111/jth.15595
https://doi.org/10.1111/jth.15595
Autor:
Guoxing Liu, Hang Cao, Guilai Liu, David Heinzmann, Hong Chen, Anja T. Umbach, Meinrad Gawaz, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 38, Iss 5, Pp 1695-1702 (2016)
Background/Aims: The polyamine oxidase inhibitor MDL-72527 (N1,N4-bis(2,3-butadienyl)-1,4-butanediamine) were expected to increase the abundance of spermine, a powerful inhibitor of platelet activation. Nothing is known, however, on the sensitivity o
Externí odkaz:
https://doaj.org/article/fa1d482c144c44e79d548e322f7b03a2
Autor:
Guoxing Liu, Guilai Liu, Madhumita Chatterjee, Anja T. Umbach, Hong Chen, Meinrad Gawaz, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 38, Iss 2, Pp 726-736 (2016)
Background/Aims: DAPT (24-diamino-5-phenylthiazole) inhibits γ-secretase, which cleaves the signaling molecule CD44, a negative regulator of platelet activation and apoptosis. CD44 is a co-receptor for macrophage migration inhibitory factor (MIF) an
Externí odkaz:
https://doaj.org/article/b23072ceb6f0498f95e7e7639a996df3