Výsledky vyhledávání - "Plasterk, R. H. A."

Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis

Autor: Smits, B. M. G., Mudde, J. B., Belt, J., Verheul, M., Olivier, J., Homberg, J., Guryev, V., Cools, A. R., Ellenbroek, B. A., Plasterk, R. H. A., Edwin Cuppen

Publikováno v: Pharmacogenetics and Genomics, 16, 3, pp. 159-69
Scopus-Elsevier
Pharmacogenetics and Genomics, 16(3), 159-169. Lippincott Williams & Wilkins
Pharmacogenetics and Genomics, 16, 159-69

Contains fulltext : 49935.pdf (Publisher’s version ) (Closed access) OBJECTIVE: The rat is one of the most important model organisms for biomedical and pharmacological research. However, the generation of novel models for studying specific aspects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::01e3dcef37e98e44f75057e8aecffc39
https://hdl.handle.net/2066/49935

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Transposase is the only nematode protein required for in vitro transposition of Tc1

Autor: J. Chris Vos, Baere, I., Plasterk, R. H. A.

Publikováno v: Genes and Development, 10(6), 755-61. Cold Spring Harbor Laboratory Press
Vos, J C, De Baere, I & Plasterk, R H A 1996, ' Transposase is the only nematode protein required for in vitro transposition of Tc1 ', Genes and Development, vol. 10, no. 6, pp. 755-61 .
Vrije Universiteit Amsterdam

The Tc1 element of Caenorhabditis elegans is a member of the most widespread class of DNA transposons known in nature. Here, we describe efficient and precise transposition of Tc1 in a cell-free system. Tc1 appears to jump by a cut-and-paste mechanis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5ff47480dad2dd6f0c8ac449dd73d047
https://research.vu.nl/en/publications/4a6c5f1f-5655-4811-aae1-3cf5b3853310