Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Plasmodium falciparum/ metabolism"'
Publikováno v:
Doritchamou, J Y A, Renn, J P, Hviid, L & Duffy, P E 2023, ' A conformational epitope in placental malaria vaccine antigen VAR2CSA : What does it teach us? ', PLoS Pathogens, vol. 19, no. 5, e1011370 . https://doi.org/10.1371/journal.ppat.1011370
VAR2CSA is the Plasmodium falciparum variant surface antigen that mediates binding of infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous spaces of the placenta, leading to placental malaria (PM). Relatively h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfb8163852760950958f00197a7304b
https://curis.ku.dk/ws/files/347695012/journal.ppat.1011370.pdf
https://curis.ku.dk/ws/files/347695012/journal.ppat.1011370.pdf
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-15 (2010)
Abstract Genome‐scale metabolic reconstructions can serve as important tools for hypothesis generation and high‐throughput data integration. Here, we present a metabolic network reconstruction and flux‐balance analysis (FBA) of Plasmodium falci
Externí odkaz:
https://doaj.org/article/aa54f29d20cf486f8ff7286518d9e058
Autor:
Sai Sundar Rajan Raghavan, Robert Dagil, Mary Lopez-Perez, Julian Conrad, Maria Rosaria Bassi, Maria del Pilar Quintana, Swati Choudhary, Tobias Gustavsson, Yong Wang, Pontus Gourdon, Michael Fokuo Ofori, Sebastian Boje Christensen, Daniel Thomas Remias Minja, Christentze Schmiegelow, Morten Agertoug Nielsen, Lea Barfod, Lars Hviid, Ali Salanti, Thomas Lavstsen, Kaituo Wang
Publikováno v:
Raghavan, S S R, Dagil, R, Lopez-Perez, M, Conrad, J, Bassi, M R, Quintana, M D P, Choudhary, S, Gustavsson, T, Wang, Y, Gourdon, P, Ofori, M F, Christensen, S B, Minja, D T R, Schmiegelow, C, Nielsen, M A, Barfod, L, Hviid, L, Salanti, A, Lavstsen, T & Wang, K 2022, ' Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA ', PLoS Pathogens, vol. 18, no. 11, e1010924 . https://doi.org/10.1371/journal.ppat.1010924
Malaria during pregnancy is a major global health problem caused by infection with Plasmodium falciparum parasites. Severe effects arise from the accumulation of infected erythrocytes in the placenta. Here, erythrocytes infected by late blood-stage p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83da916115147e423b15b96d457e2e7
https://curis.ku.dk/ws/files/326848976/journal.ppat.1010924.pdf
https://curis.ku.dk/ws/files/326848976/journal.ppat.1010924.pdf
Publikováno v:
Future Medicinal Chemistry
Future Medicinal Chemistry, Future Science, 2013, 5 (16), pp.1993-2006. ⟨10.4155/fmc.13.159⟩
Future Medicinal Chemistry, Future Science, 2013, 5 (16), pp.1993-2006. ⟨10.4155/fmc.13.159⟩
International audience; Targeting the redox metabolism of Plasmodium falciparum to create a fatal overload of oxidative stress is a route to explore the discovery of new antimalarial drugs. There are three main possibilities to target the redox metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f181f9f9422ad79d0766c1f16ca5abf
https://pubmed.ncbi.nlm.nih.gov/24175748
https://pubmed.ncbi.nlm.nih.gov/24175748
Autor:
Eric Allemand, Shiri Eshar, Christian Muchardt, Fabian Glaser, Ron Dzikowski, Rotem Karni, Yael Mandel-Gutfreund, Ariel Sebag
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2012, 40 (19), pp.9903-16. ⟨10.1093/nar/gks735⟩
Nucleic Acids Research, 2012, 40 (19), pp.9903-16. ⟨10.1093/nar/gks735⟩
Nucleic Acids Research, Oxford University Press, 2012, 40 (19), pp.9903-16. ⟨10.1093/nar/gks735⟩
Nucleic Acids Research, 2012, 40 (19), pp.9903-16. ⟨10.1093/nar/gks735⟩
International audience; Malaria parasites have a complex life cycle, during which they undergo significant biological changes to adapt to different hosts and changing environments. Plasmodium falciparum, the species responsible for the deadliest form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f24c4064dbcdda54466d9ed3a5e97b
https://hal.archives-ouvertes.fr/hal-02462833
https://hal.archives-ouvertes.fr/hal-02462833
Publikováno v:
Biology of the Cell
Biology of the Cell, Wiley, 2010, 102 (8), pp.435-45. ⟨10.1042/BC20100005⟩
Biology of the Cell, Vol. 102, No 8 (2010) pp. 435-45
Biology of the Cell, 2010, 102 (8), pp.435-45. ⟨10.1042/BC20100005⟩
Biology of the Cell, Wiley, 2010, 102 (8), pp.435-45. ⟨10.1042/BC20100005⟩
Biology of the Cell, Vol. 102, No 8 (2010) pp. 435-45
Biology of the Cell, 2010, 102 (8), pp.435-45. ⟨10.1042/BC20100005⟩
International audience; Members of the phylum Apicomplexa are motile and rapidly dividing intracellular parasites, able to occupy a large spectrum of niches by infecting diverse hosts and invading various cell types. As obligate intracellular parasit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c4a17405c7474a51e592928f96e425
https://hal.archives-ouvertes.fr/hal-00820630
https://hal.archives-ouvertes.fr/hal-00820630
Autor:
Nicolas Collin, Graciela R. Ostera, Clarissa Teixeira, José M. C. Ribeiro, Juliana Sa, Fuyuki Tokumasu, Gudrun S. Lukat-Rodgers, Sanjai Kumar, Jennifer Hume, Kenton R. Rodgers
Publikováno v:
Experimental Parasitology, vol. 127, no. 1, pp. 1-8
Nitric oxide (NO) and NO-derived reactive nitrogen species (RNS) are present in the food vacuole (FV) of Plasmodium falciparum trophozoites. The product of PFL1555w, a putative cytochrome b(5), localizes in the FV membrane, similar to what was previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddda1e00720cd4375a78e927b4352330
https://europepmc.org/articles/PMC2948613/
https://europepmc.org/articles/PMC2948613/
Autor:
Geert-Jaan van Gemert, Emmanuel Bischoff, Samir Yalaoui, Dominique Mazier, Patrick Froissard, Carine Marinach, Jean-François Franetich, Georges Snounou, Catherine Vaquero, Olivier Silvie, Anthony Siau, Peter H. David, Laurent Hannoun, Adrian J. F. Luty
Publikováno v:
PLoS Pathogens, Vol 4, Iss 8, p e1000121 (2008)
PLoS Pathogens
PLoS Pathogens, 2008, 4 (8), pp.e1000121. ⟨10.1371/journal.ppat.1000121⟩
PLoS Pathogens, Public Library of Science, 2008, 4 (8), pp.e1000121. ⟨10.1371/journal.ppat.1000121⟩
Plos Pathogens, 4, e1000121-e1000121
Plos Pathogens, 4, 8, pp. e1000121-e1000121
PLoS Pathogens
PLoS Pathogens, 2008, 4 (8), pp.e1000121. ⟨10.1371/journal.ppat.1000121⟩
PLoS Pathogens, Public Library of Science, 2008, 4 (8), pp.e1000121. ⟨10.1371/journal.ppat.1000121⟩
Plos Pathogens, 4, e1000121-e1000121
Plos Pathogens, 4, 8, pp. e1000121-e1000121
Plasmodium sporozoites are deposited in the skin by Anopheles mosquitoes. They then find their way to the liver, where they specifically invade hepatocytes in which they develop to yield merozoites infective to red blood cells. Relatively little is k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f606e06d40e89724498bd5d326117577
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18688281/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18688281/pdf/?tool=EBI
Autor:
Martin, Gengenbacher, Teresa B, Fitzpatrick, Thomas, Raschle, Karlheinz, Flicker, Irmgard, Sinning, Sylke, Müller, Peter, Macheroux, Ivo, Tews, Barbara, Kappes
Publikováno v:
Journal of Biological Chemistry, Vol. 281, No 6 (2006) pp. 3633-3641
Vitamin B6 is one of nature's most versatile cofactors. Most organisms synthesize vitamin B6 via a recently discovered pathway employing the proteins Pdx1 and Pdx2. Here we present an in-depth characterization of the respective orthologs from the mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f2c9879d932b78b99158a1d21cbc69a9
https://archive-ouverte.unige.ch/unige:89536
https://archive-ouverte.unige.ch/unige:89536
Autor:
Andrews, Katherine, Pirrit, Lindsay, Przyborski, Jude, Sanchez, Cecilia, Sterkers, Yvon, Ricken, Sigrid, Wickert, Hannes, Lepolard, Catherine, Avril, Marion, Scherf, Artur, Gysin, Jürg, Lanzer, Michael
Publikováno v:
Molecular Microbiology
Molecular Microbiology, Wiley, 2003, 49 (3), pp.655-669. ⟨10.1046/j.1365-2958.2003.03595.x⟩
Molecular Microbiology, 2003, 49 (3), pp.655-669. ⟨10.1046/j.1365-2958.2003.03595.x⟩
Molecular Microbiology, Wiley, 2003, 49 (3), pp.655-669. ⟨10.1046/j.1365-2958.2003.03595.x⟩
Molecular Microbiology, 2003, 49 (3), pp.655-669. ⟨10.1046/j.1365-2958.2003.03595.x⟩
International audience; Protection against maternal malaria has been associated with the acquisition of a specific antibody response that prevents adhesion of Plasmodium falciparum-infected erythrocytes to the glycosaminoglycan chondroitin-4-sulphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::50066d8b2c7d62a87bd9f188eb3f8831
https://pubmed.ncbi.nlm.nih.gov/12864850
https://pubmed.ncbi.nlm.nih.gov/12864850