Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Plasminogen Activators/ metabolism"'
Publikováno v:
Journal of Cellular Biochemistry, Vol. 98, No 2 (2006) pp. 267-86
Primary cultures of bovine microvascular endothelial cells (BME) isolated from the adrenal cortex, are commonly used to study vascular endothelium, but have a limited life span. To circumvent these limitations, we have immortalized BME cells with eit
Autor:
Michael S. Pepper, Lelio Orci, Roberto Montesano, Jean-Dominique Vassalli, Stefano J. Mandriota
Publikováno v:
Enzyme Protein, Vol. 49, No 1-3 (1996) pp. 138-162
Extracellular proteolysis is required for matrix degradation and the regulation of cytokine activity during angiogenesis, and this is dependent on a cohort of proteases and protease inhibitors produced by endothelial and nonendothelial cells. The pla
Publikováno v:
Thrombosis and Haemostasis, Vol. 105, No 3 (2011) pp. 461-72
Thrombosis and haemostasis
Thrombosis and haemostasis
SummaryStatins are cholesterol-lowering drugs that exert pleiotropic effects which include changes in the plasminogen activation (PA) system of endothelial cells (EC). It was the objective of this study to investigate the signal transduction pathways
Autor:
Christian Vesin, Dominique Belin, Constance Barazzone, Fabienne Tacchini-Cottier, Pierre Francois Piguet, Yves Donati
Publikováno v:
Scopus-Elsevier
Circulation, Vol. 99, No 25 (1999) pp. 3315-3321
Circulation, Vol. 99, No 25 (1999) pp. 3315-3321
Background —Urokinase plasminogen activator receptor (uPAR, CD87) is a widely distributed 55-kD, glycoprotein I–anchored surface receptor. On binding of its ligand uPA, it is known to increase leukocyte adhesion and traffic. Using genetically def
Autor:
C. Trân-Thang, Gian Dorta, P. Chaubert, E. Saraga, P. Protiva, I. Sordat, A. L. Blum, Bernard Sordat
Publikováno v:
British Journal of Cancer
British journal of cancer, vol. 77, no. 2, pp. 297-304
British journal of cancer, vol. 77, no. 2, pp. 297-304
Proteases are important for neoplastic invasion but a specific role for the plasminogen activator system in the progression of colorectal epithelial dysplasia to adenomatous lesions remains unclear. Consecutive tissue cryosections of 51 adenomas, 49
Autor:
Roland H. Gisler, Leif R. Lund, Klaus T. Preissner, Beat A. Imhof, Sandip M. Kanse, Andreas E. May
Publikováno v:
Journal of Experimental Medicine, Vol. 188, No 6 (1998) pp. 1029-1037
The Journal of Experimental Medicine
The Journal of Experimental Medicine
The urokinase receptor (CD87; uPAR) is found in close association with beta 2 integrins on leukocytes. We studied the functional consequence of this association for leukocyte adhesion and migration. In vivo, the beta 2 integrin-dependent recruitment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a66344fa3e67b4511cd6550df6deeae
https://archive-ouverte.unige.ch/unige:11455
https://archive-ouverte.unige.ch/unige:11455
Autor:
André-Pascal Sappino, Joachim Huarte, J.-D. Vasalli, Annelise Isabelle Wohlwend, Dominique Belin
Publikováno v:
Annals of the New York Academy of Sciences, Vol. 667 (1992) P. 41
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine, Vol. 165, No 2 (1987) pp. 320-339
Journal of Experimental Medicine, Vol. 165, No 2 (1987) pp. 320-339
Human monocytes/macrophages produce plasminogen activator-specific inhibitors (PAIs) that form covalent complexes with urokinase-type plasminogen activator (uPA). We have characterized two functionally and antigenically related forms of PAIs produced
Autor:
Dominique Belin, A. Estreicher, W. D. Schleuning, Annelise Isabelle Wohlwend, Jean-Dominique Vassalli
Publikováno v:
Journal of Biological Chemistry, Vol. 264, No 2 (1989) pp. 1180-1189
Human urokinase-type plasminogen activator (uPA) binds rapidly and with high affinity to a number of human cell types; this localizes plasmin generation to the close environment of the cell surface. uPA binding to HeLa and U937 cells is mediated by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4102aa647acc16096c3b5556c82d6d9e
https://archive-ouverte.unige.ch/unige:8739
https://archive-ouverte.unige.ch/unige:8739
Publikováno v:
American Journal of Physiology, Vol. 250, No 5 Pt 1 (1986) pp. C682-687
The LLC-PK1 pig kidney-derived cell line is morphologically and functionally heterogeneous. We have clonally derived three sublines that differ in their response to calcitonin and in their ability to form domes. The three clones were analyzed for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ecb9297837ca17b0ef5cf6bb41ceb47
https://archive-ouverte.unige.ch/unige:9102
https://archive-ouverte.unige.ch/unige:9102