Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Plasminogen Activator Inhibitor 1/metabolism"'
Autor:
Anni Christensen, Jeppe B. Madsen, Andrés Chana-Muñoz, Simon C. Lovell, Frank Panitz, Ernst-Martin Füchtbauer, Jan K. Jensen, Agnieszka Jendroszek, Daniel M. Dupont
Publikováno v:
Jendroszek, A, Madsen, J B, Chana-Muñoz, A, Dupont, D M, Christensen, A, Panitz, F, Füchtbauer, E-M, Lovell, S C & Jensen, J K 2019, ' Biochemical and structural analyses suggest that plasminogen activators coevolved with their cognate protein substrates and inhibitors ', The Journal of biological chemistry . https://doi.org/10.1074/jbc.RA118.005419
Jendroszek, A, Madsen, J B, Chana-Muñoz, A, Dupont, D M, Christensen, A, Panitz, F, Füchtbauer, E-M, Lovell, S C & Jensen, J K 2019, ' Biochemical and structural analyses suggest that plasminogen activators coevolved with their cognate protein substrates and inhibitors ', The Journal of Biological Chemistry, vol. 294, no. 10, pp. 3794-3805 . https://doi.org/10.1074/jbc.RA118.005419
Jendroszek, A, Madsen, J B, Chana-Muñoz, A, Dupont, D M, Christensen, A, Panitz, F, Füchtbauer, E-M, Lovell, S C & Jensen, J K 2019, ' Biochemical and structural analyses suggest that plasminogen activators coevolved with their cognate protein substrates and inhibitors ', The Journal of Biological Chemistry, vol. 294, no. 10, pp. 3794-3805 . https://doi.org/10.1074/jbc.RA118.005419
Protein sequences of members of the plasminogen activation system are present throughout the entire vertebrate phylum. This important and well-described proteolytic cascade is governed by numerous protease-substrate and protease-inhibitor interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb67139be6c77514b369259ac730ad4f
https://doi.org/10.1074/jbc.RA118.005419
https://doi.org/10.1074/jbc.RA118.005419
Assessment of the Interplay between Blood and Skin Vascular Abnormalities in Adult Purpura Fulminans
Autor:
Guillaume Hékimian, Sophie Gandrille, Keira Melican, Jean-Luc Diehl, Guillaume Duménil, Chantal Mandet, Nicolas Lerolle, Agnes Carlotti, Patrick Bruneval, Marc Pierrot, F Aubey, Vincent Caille, Delphine Borgel
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2013, 188 (6), pp.684-92. ⟨10.1164/rccm.201302-0228OC⟩
Europe PubMed Central
American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2013, 188 (6), pp.684-92. ⟨10.1164/rccm.201302-0228OC⟩
Europe PubMed Central
International audience; RATIONALE: Purpura fulminans in adults is a rare but devastating disease. Its pathophysiology is not well known. OBJECTIVES: To understand the pathophysiology of skin lesions in purpura fulminans, the interplay between circula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133ca897d6ea57a12db8a2123153bead
https://doi.org/10.1164/rccm.201302-0228oc
https://doi.org/10.1164/rccm.201302-0228oc
Autor:
Michael S. Pepper, Lelio Orci, Roberto Montesano, Jean-Dominique Vassalli, Stefano J. Mandriota
Publikováno v:
Enzyme Protein, Vol. 49, No 1-3 (1996) pp. 138-162
Extracellular proteolysis is required for matrix degradation and the regulation of cytokine activity during angiogenesis, and this is dependent on a cohort of proteases and protease inhibitors produced by endothelial and nonendothelial cells. The pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11e8a4a101ddae18a87eeea19c31baa
https://doi.org/10.1159/000468622
https://doi.org/10.1159/000468622
Autor:
Anne Estreicher, Arnaud Gos, Pia Ragno, Annelise Isabelle Wohlwend, Dominique Belin, Jean-Dominique Vassalli
Publikováno v:
Experimental Cell Research, Vol. 203, No 1 (1992) pp. 236-243
Numerous epithelial cell types produce and secrete plasminogen activators (PAs) and/or PA inhibitors (PAIs). When epithelial cells were grown on polycarbonate filters and their apical and basolateral secretion products analyzed, PA activity accumulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50fe62a5e137701b668a48b36b5c26f
https://doi.org/10.1016/0014-4827(92)90060-l
https://doi.org/10.1016/0014-4827(92)90060-l
Autor:
Scherrer, Anne Paule Marie, Wohlwend, Annelise Isabelle, Kruithof, Egbert, Vassalli, Jean-Dominique, Sappino, Pascal
Publikováno v:
British Journal of Haematology, Vol. 105, No 4 (1999) pp. 920-7
Plasminogen activation is implicated in solid tumour growth, invasion and metatastic spread. However, little is known about its role in leukaemia. We investigated the production by leukaemic cells of plasminogen activators [urokinase (uPA) and tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::07b66b707211c32d9215f7e3f301ffe5
https://pubmed.ncbi.nlm.nih.gov/10554801
https://pubmed.ncbi.nlm.nih.gov/10554801
Autor:
C. Trân-Thang, Gian Dorta, P. Chaubert, E. Saraga, P. Protiva, I. Sordat, A. L. Blum, Bernard Sordat
Publikováno v:
British Journal of Cancer
British journal of cancer, vol. 77, no. 2, pp. 297-304
British journal of cancer, vol. 77, no. 2, pp. 297-304
Proteases are important for neoplastic invasion but a specific role for the plasminogen activator system in the progression of colorectal epithelial dysplasia to adenomatous lesions remains unclear. Consecutive tissue cryosections of 51 adenomas, 49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db368288ed723c24c70a6bf03bac7a46
https://pubmed.ncbi.nlm.nih.gov/9461001
https://pubmed.ncbi.nlm.nih.gov/9461001
Publikováno v:
Laboratory Investigation, Vol. 74, No 1 (1996) pp. 253-8
Preeclampsia is characterized by maternal hypercoagulable state and intravascular coagulation, microthromboses in several organs, and impairment of uteroplacental circulation. Excessive fibrin deposition occurs in the placenta, suggesting that disord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e0bfd88bafe3cd49b7deaaff0a0d9e26
https://archive-ouverte.unige.ch/unige:47002
https://archive-ouverte.unige.ch/unige:47002
Autor:
André-Pascal Sappino, Joachim Huarte, J.-D. Vasalli, Annelise Isabelle Wohlwend, Dominique Belin
Publikováno v:
Annals of the New York Academy of Sciences, Vol. 667 (1992) P. 41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf165904ed3a0ee4e0d9dcd9ef57670
https://pubmed.ncbi.nlm.nih.gov/1309061
https://pubmed.ncbi.nlm.nih.gov/1309061
Autor:
Paoni, N. F., Keyt, B. A., Refino, C. J., Chow, A. M., Nguyen, H. V., Berleau, L. T., Badillo, J., Pena, L. C., Brady, K., Wurm, F. M.
Site directed mutagenesis was used to construct a t-PA variant that contains an additional glycosylation site in the first kringle domain (T103N) combined with a tetra-alanine substitution in the protease domain (KHRR 296-299 AAAA). This combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______185::9855b76a794c12294b3b80513ec55e77
https://infoscience.epfl.ch/record/105005
https://infoscience.epfl.ch/record/105005