Výsledky vyhledávání - "Plasminogen/ metabolism"

Fibrin clot structure - pro-fibrinolytic effect of oral contraceptives in apparently healthy women

Autor: Ulrich Winkler, Johannes Jakobsen Sidelmann, Andrea H. Krug, Jørgen Jespersen, Jørgen Gram, Cornelis Kluft

Publikováno v: Sidelmann, J J, Kluft, C, Krug, A H, Winkler, U, Jespersen, J & Gram, J B 2017, ' Fibrin clot structure-pro-fibrinolytic effect of oral contraceptives in apparently healthy women ', Thrombosis and Haemostasis, vol. 117, no. 4, pp. 700-705 . https://doi.org/10.1160/TH16-10-0748

SummaryFibrin metabolism is influenced by many factors. The velocity of fibrin formation, genetic polymorphisms, fibrinolytic features and the structure of the fibrin clot are determinants of fibrin turnover. Oral contraceptives (OCs) have significan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6968af83130bc95076779ab188fdf54
https://pubmed.ncbi.nlm.nih.gov/28150855

Zobrazit plný text záznamu

Human single-chain urokinase is activated by the omptins PgtE of Salmonella enterica and Pla of Yersinia pestis despite mutations of active site residues

Autor: Hanna M, Järvinen, Liisa, Laakkonen, Johanna, Haiko, Tiira, Johansson, Katri, Juuti, Marjo, Suomalainen, Carmen, Buchrieser, Nisse, Kalkkinen, Timo K, Korhonen

Publikováno v: Molecular Microbiology
Molecular Microbiology, Wiley, 2013, 89 (3), pp.507-517. ⟨10.1111/mmi.12293⟩
Molecular Microbiology, 2013, 89 (3), pp.507-517. ⟨10.1111/mmi.12293⟩

International audience; Fibrinolysis is important in cell migration and tightly regulated by specific inhibitors and activators; of the latter, urokinase (uPA) associates with enhancement of cell migration. Active uPA is formed through cleavage of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a4502f4fa4f2463202bed6e9fbec91ad
https://hal-pasteur.archives-ouvertes.fr/pasteur-01336155

Zobrazit plný text záznamu

A region of tissue plasminogen activator that affects plasminogen activation differentially with various fibrin(ogen)-related stimulators

Autor: R. van Reis, D. Eastman, D. L. Higgins, Florian M. Wurm

Publikováno v: Biochemistry. 31:419-422

The dissolution of blood clots by plasmin is normally initiated in vivo by the activation of plasminogen to plasmin through the activity of tissue plasminogen activator (t-PA). The rate of plasminogen activation can be stimulated several orders of ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d306e50324697aacaffd7a6ee37ce429
https://doi.org/10.1021/bi00117a016

Zobrazit plný text záznamu

Plasminogen activation in human acute leukaemias

Autor: Scherrer, Anne Paule Marie, Wohlwend, Annelise Isabelle, Kruithof, Egbert, Vassalli, Jean-Dominique, Sappino, Pascal

Publikováno v: British Journal of Haematology, Vol. 105, No 4 (1999) pp. 920-7

Plasminogen activation is implicated in solid tumour growth, invasion and metatastic spread. However, little is known about its role in leukaemia. We investigated the production by leukaemic cells of plasminogen activators [urokinase (uPA) and tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::07b66b707211c32d9215f7e3f301ffe5
https://pubmed.ncbi.nlm.nih.gov/10554801

Zobrazit plný text záznamu

Alterations in plasminogen activation correlate with epithelial cell dysplasia grading in colorectal adenomas

Autor: C. Trân-Thang, Gian Dorta, P. Chaubert, E. Saraga, P. Protiva, I. Sordat, A. L. Blum, Bernard Sordat

Publikováno v: British Journal of Cancer
British journal of cancer, vol. 77, no. 2, pp. 297-304

Proteases are important for neoplastic invasion but a specific role for the plasminogen activator system in the progression of colorectal epithelial dysplasia to adenomatous lesions remains unclear. Consecutive tissue cryosections of 51 adenomas, 49

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db368288ed723c24c70a6bf03bac7a46
https://pubmed.ncbi.nlm.nih.gov/9461001

Zobrazit plný text záznamu

Further characterization and thrombolytic activity in a rat model of a fibrinogenase from Vipera lebetina venom

Autor: Mohamed Elayeb, Habib Karoui, Ahmed Chabchoub, Koussay Dellagi, Ammar Gasmi, S. Guermazi

Publikováno v: Thrombosis Research
Thrombosis Research, Elsevier, 1997, 86 (3), pp.233-242. ⟨10.1016/S0049-3848(97)00066-2⟩

International audience; Vipera lebetina fibrinogenase (VIF) was shown to render fibrinogen incoagulable and to solubilize fibrin. The fibrinogenolytic activity of this enzyme was found to be 33 mg fibrinogen/min/mg protein. The study of the specifici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed4758c0c499d929c2598423f49aeb7
https://pubmed.ncbi.nlm.nih.gov/9175244

Zobrazit plný text záznamu

Group B Streptococcus Hijacks the Host Plasminogen System to Promote Brain Endothelial Cell Invasion

Autor: Patrick Trieu-Cuot, Kwang Sik Kim, Margarida Lima, Adília Ribeiro, Paula Ferreira, Joana Alves, Vanessa Magalhães, Elva Bonifácio Andrade

Publikováno v: PLoS ONE
PLoS ONE, 2013, 8 (5), pp.e63244. ⟨10.1371/journal.pone.0063244⟩
PLoS ONE, Vol 8, Iss 5, p e63244 (2013)
PLoS ONE, Public Library of Science, 2013, 8 (5), pp.e63244. ⟨10.1371/journal.pone.0063244⟩
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP

Group B Streptococcus (GBS) is the leading cause of meningitis in neonates. We have previously shown that plasminogen, once recruited to the GBS cell surface and converted into plasmin by host-derived activators, leads to an enhancement of bacterial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d9232f0233c128f6d4da477d630a20
https://doi.org/10.1371/journal.pone.0063244

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání