Zobrazeno 1 - 10
of 958
pro vyhledávání: '"Plasmid stability"'
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Plasmid-borne Type II restriction–modification (RM) systems mediate post-segregational killing (PSK). PSK is thought to be caused by the dilution of restriction and modification enzymes during cell division, resulting in accumulation of un
Externí odkaz:
https://doaj.org/article/f40b89ecfb4d40dcbf7c64f488ae9a4d
Autor:
Siyan Zhou, Linlin Zhao, Wenjie Zuo, Yilin Zheng, Ping Zhang, Yanan Sun, Yang Wang, Guocheng Du, Zhen Kang
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 1, Pp 165-175 (2024)
The probiotic bacterium Escherichia coli Nissle 1917 (EcN) holds significant promise for use in clinical and biological industries. However, the reliance on antibiotics to maintain plasmid-borne genes has overshadowed its benefits. In this study, we
Externí odkaz:
https://doaj.org/article/cd6322c0c9fe4ed7a3186e793c9ddc16
Autor:
Yongkui Chen, Ying-Xian Goh, Peifei Li, Jiahao Guan, Yanjie Chao, Hongping Qu, Hong-Yu Ou, Xiaoli Wang
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTHypervirulent Klebsiella pneumoniae isolates have been increasingly reported worldwide, especially hypervirulent drug-resistant variants owing to the acquisition of a mobilizable virulence plasmid by a carbapenem-resistant strain. This pLVPK-
Externí odkaz:
https://doaj.org/article/30c89dbc01304fab8b71c0b1952b6cc4
Akademický článek
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Autor:
Jun Yang, Renjie Wu, Qiang Xia, Jingjing Yu, Ling-Xian Yi, Ying Huang, Meixin Deng, Wan-Yun He, Yuman Bai, Luchao Lv, Vincent Burrus, Chengzhen Wang, Jian-Hua Liu
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Conjugative plasmids play a vital role in bacterial evolution and promote the spread of antibiotic resistance. They usually cause fitness costs that diminish the growth rates of the host bacteria. Compensatory mutations are known as an effec
Externí odkaz:
https://doaj.org/article/a1c5c1f8dc79490592a229daf8461195
Development of a thiostrepton-free system for stable production of PLD in Streptomyces lividans SBT5
Autor:
Juntan Wang, Haihua Zhu, Huiyi Shang, Bishan Guo, Mengxue Zhang, Fayun Wang, Lipan Zhang, Jun Xu, Hui Wang
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Background Phospholipase D (PLD) is highly valuable in the food and medicine industries, where it is used to convert low-cost phosphatidylcholine into high-value phospholipids (PLs). Despite being overexpressed in Streptomyces, PLD productio
Externí odkaz:
https://doaj.org/article/3008d8b68b5947f2836bb3d1577e255e
Akademický článek
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Autor:
Saif S. Al-Janabi, Heba Shawky, Amr A. El-Waseif, Ayman A. Farrag, Tarek M. Abdelghany, Dina E. El-Ghwas
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Owing to its remarkable mechanical properties that surpass the plant-based cellulose, bacterial cellulose production has been targeted for commercialization during the last few years. However, the large-scale production of cellulo
Externí odkaz:
https://doaj.org/article/158ba84c86f24096a801f1581a4941a5
Autor:
Samiratu Mahazu, Isaac Prah, Yusuke Ota, Takaya Hayashi, Yoko Nukui, Masato Suzuki, Yoshihiko Hoshino, Yukihiro Akeda, Toshihiko Suzuki, Tomoko Ishino, Anthony Ablordey, Ryoichi Saito
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT IncX3 and IncL plasmids have been named as catalysts advancing dissemination of blaOXA-181 and blaOXA-48 genes. However, their impact on the performance of host cells is vastly understudied. Genetic characteristics of blaOXA-48- and blaOXA-1
Externí odkaz:
https://doaj.org/article/9554fa53439a4f79a7b36ad36a3907ff
Autor:
Jin-Fei Zhang, Liang-Xing Fang, Man-Xia Chang, Ming Cheng, Hui Zhang, Teng-Fei Long, Qian Li, Xin-lei Lian, Jian Sun, Xiao-Ping Liao, Ya-Hong Liu
Publikováno v:
mSystems, Vol 7, Iss 5 (2022)
ABSTRACT Understanding the fitness costs associated with plasmid carriage is a key to better understanding the mechanisms of plasmid maintenance in bacteria. In the current work, we performed multiple serial passages (63 days, 627.8 generations) to i
Externí odkaz:
https://doaj.org/article/7053ddfd2aa44295a4e7ace1bca50d50