Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Plasma membrane monoamine transporter"'
Autor:
Melodi A. Bowman, Jorge A. Gomez, Nathan C. Mitchell, Anne M. Wells, Melissa Vitela, Kyra M. Clarke, Rebecca E. Horton, Wouter Koek, Lynette C. Daws
Publikováno v:
Cells, Vol 11, Iss 15, p 2454 (2022)
Selective serotonin reuptake inhibitors (SSRIs) are less efficacious in treating depression in children than in adults. SSRIs block serotonin uptake via the high-affinity, low-capacity serotonin transporter. However, the low-affinity, high-capacity o
Externí odkaz:
https://doaj.org/article/1e8fa113ae6d49c6a4e5e94164ae7fa9
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1392 (2022)
Paeonol is a naturally occurring phenolic agent that attenuates neurotoxicity in neurodegenerative diseases. We aimed to investigate the antioxidant and protective effects of paeonol and determine its transport mechanism in wild-type (WT; NSC-34/hSOD
Externí odkaz:
https://doaj.org/article/f79c1d4aa421454aa60ab939a4b4ae2f
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13420 (2021)
A lack of effective treatment and sex-based disparities in psychostimulant addiction and overdose warrant further investigation into mechanisms underlying the abuse-related effects of amphetamine-like stimulants. Uptake-2 transporters such as organic
Externí odkaz:
https://doaj.org/article/f61bf1e3db5343b394fe599692b32df6
Akademický článek
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Publikováno v:
Physiological Reports, Vol 7, Iss 22, Pp n/a-n/a (2019)
Abstract Serotonin (5‐HT) accumulates in the heart during myocardial ischemia and induces deleterious effects on the cardiomyocytes through receptor‐dependent and monoamine oxidase‐dependent pathways. We aimed to clarify the involvement of extr
Externí odkaz:
https://doaj.org/article/b67ebee1854d4b2b8d50bdff0588a9ed
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7581 (2020)
Major depressive disorder is typically treated with selective serotonin reuptake inhibitors (SSRIs), however, SSRIs take approximately six weeks to produce therapeutic effects, if any. Not surprisingly, there has been great interest in findings that
Externí odkaz:
https://doaj.org/article/f7f66c757fe54fa68d10904ad02857a8
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1697-1707 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Small intestine in vitro models play a crucial role in drug transport research. Although conventional 2D cell culture models, such as Caco-2 monolayer, possess many advantages, they should be interpreted with caution because they have relatively poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd5440f02c300c8abab983b55b9cdda
https://doi.org/10.1016/j.apsb.2020.12.002
https://doi.org/10.1016/j.apsb.2020.12.002
Akademický článek
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Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7581, p 7581 (2020)
Volume 21
Issue 20
International Journal of Molecular Sciences, Vol 21, Iss 7581, p 7581 (2020)
Major depressive disorder is typically treated with selective serotonin reuptake inhibitors (SSRIs), however, SSRIs take approximately six weeks to produce therapeutic effects, if any. Not surprisingly, there has been great interest in findings that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b99e87befa2ba6478dc1130e6c1a5c6
Akademický článek
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