Zobrazeno 1 - 10 of 218 pro vyhledávání: '"Placental cotyledon"'
1
Placental perfusion and mathematical modelling
Autor: Jane K. Cleal, Bram G. Sengers, Rohan M. Lewis
Publikováno v: Placenta. 93:43-48
The isolated perfused placental cotyledon technique has led to numerous advances in placental biology. Combining placental perfusion with mathematical modelling provides an additional level of insight into placental function. Mathematical modelling o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576a4e8bd49861be2d6f3717328f82a2
https://doi.org/10.1016/j.placenta.2020.02.015
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2
PrPres in placental tissue following experimental transmission of atypical scrapie in ARR/ARR sheep is not infectious by Tg338 mouse bioassay
Autor: Robert B. Piel, Valerie R. McElliott, James B. Stanton, Dongyue Zhuang, Sally A. Madsen-Bouterse, Linda K. Hamburg, Robert D. Harrington, David A. Schneider
Publikováno v: PLoS ONE, Vol 17, Iss 1 (2022)
PLoS ONE, Vol 17, Iss 1, p e0262766 (2022)
PLoS ONE
Nor98-like atypical scrapie is a sporadic disease that affects the central nervous system of sheep and goats that, in contrast to classical scrapie, is not generally regarded as naturally transmissible. However, infectivity has been demonstrated via
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac8a0941a0d6e171de607b7f4890629
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782414/?tool=EBI
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3
A double deletion prevents replication of the pestivirus bovine viral diarrhea virus in the placenta of pregnant heifers
Autor: Jolene Carlson, Robert Kammerer, Jens Peter Teifke, Julia Sehl-Ewert, Christiane Pfarrer, Gregor Meyers
Publikováno v: PLoS Pathogens, Vol 17, Iss 12 (2021)
PLoS Pathogens, Vol 17, Iss 12, p e1010107 (2021)
PLoS Pathogens
In contrast to wild type bovine viral diarhea virus (BVDV) specific double deletion mutants are not able to establish persistent infection upon infection of a pregnant heifer. Our data shows that this finding results from a defect in transfer of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce6b9598c5baf9d4f2e37d42342bc61
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654156/?tool=EBI
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4
Placental transfer of Letermovir & Maribavir in the ex vivo human cotyledon perfusion model. New perspectives for in utero treatment of congenital cytomegalovirus infection
Autor: Julien Stirnemann, Valentine Faure Bardon, Minh Patrick Lê, Gilles Peytavin, Elisabeth Elefant, Yves Ville, Tiffany Guilleminot, Marianne Leruez-Ville
Publikováno v: PLoS ONE
PLoS ONE, 2020, 15 (4), pp.e0232140. ⟨10.1371/journal.pone.0232140⟩
PLoS ONE, Public Library of Science, 2020, 15 (4), pp.e0232140. ⟨10.1371/journal.pone.0232140⟩
PLoS ONE, Vol 15, Iss 4, p e0232140 (2020)
International audience; Background: Congenital cytomegalovirus infection can lead to severe sequelae. When fetal infection is confirmed, we hypothesize that fetal treatment could improve the outcome. Maternal oral administration of an effective drug
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cbdec4039d4c0ce42a8ac23daf66b7c
https://www.hal.inserm.fr/inserm-02891983
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5
Methodological Approaches to Evaluate Fetal Drug Exposure
Autor: Gabrielle Lui, Frantz Foissac, Jean-Marc Tréluyer, Naïm Bouazza, Sihem Benaboud, Saik Urien, Déborah Hirt
Publikováno v: Current Pharmaceutical Design. 25:496-504
Background: Drug prescriptions are usual during pregnancy, however, women and their fetuses still remain an orphan population with regard to drugs efficacy and safety. Most xenobiotics diffuse through the placenta and some of them can alter fetus dev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36f42a7c9749a1e7e175eea3b5c9726
https://doi.org/10.2174/1381612825666190319102812
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6
Comparative pharmacokinetics and pharmacokinetic/pharmacodynamic analysis by nonlinear mixed-effects modeling of cefquinome in nonpregnant, pregnant, and lactating goats after intravenous and intramuscular administration
Autor: Nicolás Javier Litterio, María del Pilar Zarazaga, Martín Alejandro Himelfarb, Juan Manuel Serrano-Rodríguez, Manuel Ignacio San Andrés-Larrea, Augusto Matías Lorenzutti
Publikováno v: Litterio, Nicolás Javier ORCID: https://orcid.org/0000-0002-8114-0579 , Lorenzutti, Augusto Matías ORCID: https://orcid.org/0000-0002-9799-4499 , Zarazaga, María del Pilar ORCID: https://orcid.org/0000-0001-6195-7744 , Himelfarb, Martín Alejandro ORCID: https://orcid.org/0000-0001-7190-1103 , San Andrés-Larrea, Manuel Ignacio ORCID: https://orcid.org/0000-0003-1829-6113 and Serrano-Rodríguez, Juan Manuel ORCID: https://orcid.org/0000-0001-5817-5514 (2021) Comparative pharmacokinetics and pharmacokinetic/pharmacodynamic analysis by nonlinear mixed-effects modeling of cefquinome in nonpregnant, pregnant, and lactating goats after intravenous and intramuscular administration. Journal of Veterinary Pharmacology and Therapeutics, 44 (1). ISSN 0140-7783
Cefquinome is a fourth-generation cephalosporin that is used empirically in goats. Different physiologic factors like pregnancy or lactation could determine the pharmacokinetic behavior of drugs in the organism. The objectives of this study are to (a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25dc351c581d0ce5070d58391ab740d2
https://www.scopus.com/redirect/linking.uri?targetURL=https://doi.org/10.1111/jvp.12900&locationID=1&categoryID=4&eid=2-s2.0-85089175853&issn=01407783&linkType=ViewAtPublisher&year=2021&origin=recordpage&dig=b2da6d8305d4ba5cb89475a1b8451532
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7
The 1B vaccine strain of Chlamydia abortus produces placental pathology indistinguishable from a wild type infection
Autor: David Frew, Sergio Gastón Caspe, Sean Wattegedera, Gary Entrican, Francesca Chianini, Elspeth Milne, Javier Palarea-Albaladejo, David Longbottom, Morag Livingstone, Kevin Aitchison, Neil Sargison, Tom N. McNeilly
Publikováno v: Caspe, G, Livingstone, M, Frew, D, Aitchison, K, Wattegedera, S, Entrican, G, Palarea-Albaladejo, J, McNeilly, T, Milne, E, Sargison, N, Longbottom, D & Chianini, F 2020, ' The 1B vaccine strain of Chlamydia abortus produces placental pathology indistinguishable from a wild type infection ', PLoS ONE . https://doi.org/10.1371/journal.pone.0242526
PLoS ONE, Vol 15, Iss 11, p e0242526 (2020)
PLoS ONE
PLoS ONE 15 (11) : e0242526. (2020)
INTA Digital (INTA)
Instituto Nacional de Tecnología Agropecuaria
instacron:INTA
Chlamydia abortus is one of the most commonly diagnosed causes of infectious abortion in small ruminants worldwide. Control of the disease (Enzootic Abortion of Ewes or EAE) is achieved using the commercial live, attenuated C. abortus 1B vaccine stra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aba8c3ab1add080060e25bd8a2157c9
https://hdl.handle.net/20.500.11820/a0263503-88fc-4cdc-828b-7d38c92def98
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8
Transcriptome-wide analysis of the SCNT bovine abnormal placenta during mid- to late gestation
Autor: Jiaqi Zhang, Zhong Zheng, Xiaohu Su, Zhuying Wei, Li Zhang, Lei Yang, Guangpeng Li, Guangqi Gao, Chunling Bai, Guanghua Su, Xiuying Wang, Shenyuan Wang, Ziru Guo, Xiao Liu
Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
The dysfunction of placenta is common in somatic cell nuclear transfer (SCNT) cloned cattle and would cause aberrant fetal development and even abortion, which occurred with highest rate at the mid- to late gestation. However, the mechanism of abnorm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6c525977bfd7076d9826713243d1a4
https://doi.org/10.1038/s41598-019-56566-w
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9
Placental transfer and tissue accumulation of dolutegravir in the ex vivo human cotyledon perfusion model
Autor: Mandelbrot, Laurent, Ceccaldi, Pierre-François, Duro, Dominique, Lê, Minh, Pencolé, Lucile, Peytavin, Gilles
Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2019, 14 (8), pp.e0220323. ⟨10.1371/journal.pone.0220323⟩
PLoS ONE, 2019, 14 (8), pp.e0220323. ⟨10.1371/journal.pone.0220323⟩
PLoS ONE, Vol 14, Iss 8, p e0220323 (2019)
ObjectiveTo determine the transplacental pharmacokinetics of the HIV integrase inhibitor dolutegravir.Study designMaternal-to-fetal transfer across the term human placenta was investigated with the ex-vivo dually perfused cotyledon model, in 5 closed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7d4c7c3c6814aae486f7ce55d9cff606
http://europepmc.org/articles/PMC6692001
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10
Formulation effects on paclitaxel transfer and uptake in the human placenta
Autor: Mansi Shah, Sanaalarab Al-Enazy, Shariq Ali, Norah A. Albekairi, Tatiana N. Nanovskaya, Svetlana Patrikeeva, Erik Rytting, Mahmoud Ahmed
Publikováno v: Nanomedicine: Nanotechnology, Biology and Medicine. 33:102354
Diagnosis and treatment of breast cancer in pregnancy can result in morbidity and mortality for the mother and fetus. Many new paclitaxel nanoformulations commercially available worldwide for breast cancer treatment are being adopted due to favorable
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2a7944acfe0f49d3d4dd04a7ff69e1
https://doi.org/10.1016/j.nano.2020.102354
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