Zobrazeno 1 - 10
of 335
pro vyhledávání: '"Placenta/metabolism"'
Publikováno v:
Doritchamou, J Y A, Renn, J P, Hviid, L & Duffy, P E 2023, ' A conformational epitope in placental malaria vaccine antigen VAR2CSA : What does it teach us? ', PLoS Pathogens, vol. 19, no. 5, e1011370 . https://doi.org/10.1371/journal.ppat.1011370
VAR2CSA is the Plasmodium falciparum variant surface antigen that mediates binding of infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous spaces of the placenta, leading to placental malaria (PM). Relatively h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfb8163852760950958f00197a7304b
https://curis.ku.dk/ws/files/347695012/journal.ppat.1011370.pdf
https://curis.ku.dk/ws/files/347695012/journal.ppat.1011370.pdf
Autor:
Ida Sola, Valentina Karin‑Kujundzic, Frane Paic, Lada Lijovic, Mislav Glibo, Nikola Serman, Tihana Duic, Anita Skrtic, Krunoslav Kuna, Semir Vranic, Ljiljana Serman
Placental insufficiency is a common cause of intrauterine growth restriction (IUGR). It affects ~10% of pregnancies and increases fetal and neonatal morbidity and mortality. Although Wnt and Hh pathways are crucial for embryonic development and place
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198042dc83dc8282d4c80692ceb07f04
https://doi.org/10.3892/mmr.2022.12914
https://doi.org/10.3892/mmr.2022.12914
Autor:
Dusza, Hanna M, Katrukha, Eugene A, Nijmeijer, Sandra M, Akhmanova, Anna, Vethaak, A Dick, Walker, Douglas I, Legler, Juliette, IRAS OH Toxicology, Sub Cell Biology, Dep Population Health Sciences, Celbiologie
Publikováno v:
Environmental Health Perspectives, 130(9), 1. Public Health Services, US Dept of Health and Human Services
Dusza, H M, Katrukha, E A, Nijmeijer, S M, Akhmanova, A, Vethaak, A D, Walker, D I & Legler, J 2022, ' Uptake, Transport, and Toxicity of Pristine and Weathered Micro-and Nanoplastics in Human Placenta Cells ', Environmental Health Perspectives, vol. 130, no. 9, 97006, pp. 1-14 . https://doi.org/10.1289/EHP10873
Environmental Health Perspectives, 130(9):97006, 1-14. Public Health Services, US Dept of Health and Human Services
Dusza, H M, Katrukha, E A, Nijmeijer, S M, Akhmanova, A, Vethaak, A D, Walker, D I & Legler, J 2022, ' Uptake, Transport, and Toxicity of Pristine and Weathered Micro-and Nanoplastics in Human Placenta Cells ', Environmental Health Perspectives, vol. 130, no. 9, 97006, pp. 1-14 . https://doi.org/10.1289/EHP10873
Environmental Health Perspectives, 130(9):97006, 1-14. Public Health Services, US Dept of Health and Human Services
BACKGROUND: The first evidence of micro- and nanoplastic (MNP) exposure in the human placenta is emerging. However, the toxicokinetics and toxicity of MNPs in the placenta, specifically environmentally relevant particles, remain unclear. OBJECTIVES:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85587dc125b4218a2e9a38ac227c6e92
https://dspace.library.uu.nl/handle/1874/423816
https://dspace.library.uu.nl/handle/1874/423816
Autor:
Ana Katušić-Bojanac, Milvija Plazibat, Marta Himelreich-Perić, Katarina Eck-Raković, Jure Krasić, Nino Sinčić, Gordana Jurić-Lekić, Davor Ježek, Floriana Bulić-Jakuš
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 8861
The teratogenic activity of valproate (VPA), an antiepileptic and an inhibitor of histone deacetylase (HDACi), is dose-dependent in humans. Previous results showed that VPA impairs in vitro development and neural differentiation of the gastrulating e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94172e33185d6c105d2d22ab302ee8b
Autor:
Alan Šerman, Luka Kakarigi, Valentina Karin-Kujundzic, Semir Vranic, Frane Paić, Paula Slatina, Ida Marija Sola, Ljiljana Šerman, Anita Škrtić
Publikováno v:
Bosnian Journal of Basic Medical Sciences
Dishevelled family proteins (DVL1, DVL2, and DVL3) are cytoplasmic mediators involved in canonical and non-canonical Wnt signaling that are important in embryonic development. The role of DVL proteins in the placental tissue remains mostly unknown. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652cbdbb1e12cf298937b581757f1642
http://europepmc.org/articles/PMC8292871
http://europepmc.org/articles/PMC8292871
Autor:
Susan L. Greenwood, Kirsty M.M. Vincent, Colin P. Sibley, Michelle Desforges, Christina Hayward, Kirsty McIntyre, Xiaojia Li, Mark Dilworth
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Mcintyre, K, Vincent, K, Hayward, C, Li, X, Sibley, C, Desforges, M, Greenwood, S & Dilworth, M 2020, ' Human placental uptake of glutamine and glutamate is reduced in fetal growth restriction ', Scientific Reports, vol. 10, no. 1, 16197 . https://doi.org/10.1038/s41598-020-72930-7
Mcintyre, K, Vincent, K, Hayward, C, Li, X, Sibley, C, Desforges, M, Greenwood, S & Dilworth, M 2020, ' Human placental uptake of glutamine and glutamate is reduced in fetal growth restriction ', Scientific Reports, vol. 10, no. 1, 16197 . https://doi.org/10.1038/s41598-020-72930-7
Fetal growth restriction (FGR) is a significant risk factor for stillbirth, neonatal complications and adulthood morbidity. Compared with those of appropriate weight for gestational age (AGA), FGR babies have smaller placentas with reduced activity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd054bf78226a9d7bea4caf28de9810a
http://link.springer.com/article/10.1038/s41598-020-72930-7
http://link.springer.com/article/10.1038/s41598-020-72930-7
Autor:
Maximilian Brinkhaus, Elvera J. van der Kooi, Arthur E. H. Bentlage, Pleuni Ooijevaar-de Heer, Ninotska I. L. Derksen, Theo Rispens, Gestur Vidarsson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Scientific reports, 12(1):62. Nature Publishing Group
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Scientific reports, 12(1):62. Nature Publishing Group
The neonatal Fc receptor (FcRn) is known to mediate placental transfer of IgG from mother to unborn. IgE is widely known for triggering immune responses to environmental antigens. Recent evidence suggests FcRn-mediated transplacental passage of IgE d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca882c4585d682e673574c7149be9ca
https://doi.org/10.1038/s41598-021-03852-1
https://doi.org/10.1038/s41598-021-03852-1
Autor:
Sai Sundar Rajan Raghavan, Robert Dagil, Mary Lopez-Perez, Julian Conrad, Maria Rosaria Bassi, Maria del Pilar Quintana, Swati Choudhary, Tobias Gustavsson, Yong Wang, Pontus Gourdon, Michael Fokuo Ofori, Sebastian Boje Christensen, Daniel Thomas Remias Minja, Christentze Schmiegelow, Morten Agertoug Nielsen, Lea Barfod, Lars Hviid, Ali Salanti, Thomas Lavstsen, Kaituo Wang
Publikováno v:
Raghavan, S S R, Dagil, R, Lopez-Perez, M, Conrad, J, Bassi, M R, Quintana, M D P, Choudhary, S, Gustavsson, T, Wang, Y, Gourdon, P, Ofori, M F, Christensen, S B, Minja, D T R, Schmiegelow, C, Nielsen, M A, Barfod, L, Hviid, L, Salanti, A, Lavstsen, T & Wang, K 2022, ' Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA ', PLoS Pathogens, vol. 18, no. 11, e1010924 . https://doi.org/10.1371/journal.ppat.1010924
Malaria during pregnancy is a major global health problem caused by infection with Plasmodium falciparum parasites. Severe effects arise from the accumulation of infected erythrocytes in the placenta. Here, erythrocytes infected by late blood-stage p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83da916115147e423b15b96d457e2e7
https://curis.ku.dk/ws/files/326848976/journal.ppat.1010924.pdf
https://curis.ku.dk/ws/files/326848976/journal.ppat.1010924.pdf
Autor:
Amal Fahmi, Thomas Démoulins, David Baud, Fabian Blank, Blandina I. Oliveira Esteves, Lisamaria Bracher, Beatrice Zumkehr, Marco P. Alves, Volker Thiel, Carlos Wotzkow, Melanie Brügger
Publikováno v:
Cell reports. Medicine, vol. 2, no. 12, pp. 100456
Cell Reports Medicine
Fahmi, Amal; Brügger, Melanie; Démoulins, Thomas; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Bracher, Lisamaria; Wotzkow, Carlos; Blank, Fabian; Thiel, Volker; Baud, David; Alves, Marco P. (2021). SARS-CoV-2 can infect and propagate in human placenta explants. Cell reports. Medicine, 2(12), p. 100456. Elsevier 10.1016/j.xcrm.2021.100456
Cell Reports Medicine
Fahmi, Amal; Brügger, Melanie; Démoulins, Thomas; Zumkehr, Beatrice; Oliveira Esteves, Blandina I.; Bracher, Lisamaria; Wotzkow, Carlos; Blank, Fabian; Thiel, Volker; Baud, David; Alves, Marco P. (2021). SARS-CoV-2 can infect and propagate in human placenta explants. Cell reports. Medicine, 2(12), p. 100456. Elsevier 10.1016/j.xcrm.2021.100456
The ongoing SARS-CoV-2 pandemic continues to lead to high morbidity and mortality. During pregnancy, severe maternal and neonatal outcomes and placental pathological changes have been described. We evaluate SARS-CoV-2 infection at the maternal-fetal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9099de6f73745f5ba3330a3b9887536d
https://serval.unil.ch/notice/serval:BIB_2C84D160E117
https://serval.unil.ch/notice/serval:BIB_2C84D160E117
Autor:
Lotte Goyvaerts, Anica Schraenen, Katleen Lemaire, Peter in’t Veld, Ilse Smolders, Luc Maroteaux, Frans Schuit
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 15816
During mouse pregnancy placental lactogens stimulate prolactin receptors on pancreatic islet beta cells to induce expression of the tryptophan hydroxylase Tph1, resulting in the synthesis and secretion of serotonin. Presently, the functional relevanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfd1eebe58634988f955cb0b8a472ff
https://doi.org/10.3390/ijms232415816
https://doi.org/10.3390/ijms232415816