Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Placenta/drug effects"'
Autor:
Nikola Sobočan, Marta Himelreich-Perić, Ana Katušić-Bojanac, Jure Krasić, Nino Sinčić, Željka Majić, Gordana Jurić-Lekić, Ljiljana Šerman, Andreja Marić, Davor Ježek, Floriana Bulić-Jakuš
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 603
International Journal of Molecular Sciences, Vol 23, Iss 603, p 603 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 603, p 603 (2022)
International Journal of Molecular Sciences
Antioxidant N-tert-Butyl-α-phenylnitron (PBN) partly protected embryos from the negative effects of a DNA demethylating drug 5-azacytidine during pregnancy. Our aim was to investigate PBN’s impact on the placenta. Fischer rat dams were treated on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdb5992b1798da16989b4cf40783133
Autor:
Dimopoulou, Myrto, Verhoef, Aart, Gomes, Caroline A, van Dongen, Catharina W, Rietjens, Ivonne M C M, Piersma, Aldert H, van Ravenzwaay, Bennard, Sub RIVM, dIRAS RA-1
Publikováno v:
Toxicology Letters, 286, 10-21
Toxicology Letters, 286, 10. Elsevier Ireland Ltd.
Toxicology Letters 286 (2018)
Toxicology Letters, 286, 10. Elsevier Ireland Ltd.
Toxicology Letters 286 (2018)
In the present study, we show the value of combining toxico-dynamic and -kinetic in vitro approaches for embryotoxicity testing of azoles. Both the whole embryo culture (WEC) and the embryonic stem cells test (EST) predicted the in vivo potency ranki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7c0cd68481a06c942188279cd9a67d
https://research.wur.nl/en/publications/a-comparison-of-the-embryonic-stem-cell-test-and-whole-embryo-cul
https://research.wur.nl/en/publications/a-comparison-of-the-embryonic-stem-cell-test-and-whole-embryo-cul
Autor:
Erik Rytting, Marie Sønnegaard Poulsen, Marie Frederiksen, Lisbeth E. Knudsen, Tina Mose, Giuseppina Zuri, Maria Helena Guerra Andersen, Line Mathiesen, Jeanette K.S. Nielsen, Caroline Pehrson, Thit A. Mørck
Publikováno v:
Mathiesen, L, Mørck, T A, Zuri, G, Andersen, M H, Pehrson, C, Frederiksen, M, Mose, T, Rytting, E, Poulsen, M S, Nielsen, J K & Knudsen, L E 2014, ' Modelling of human transplacental transport as performed in Copenhagen, Denmark ', Basic & Clinical Pharmacology & Toxicology, vol. 115, no. 1, pp. 93-100 . https://doi.org/10.1111/bcpt.12228
Mathiesen, L, Morck, T A, Zuri, G, Andersen, M H, Pehrson, C, Frederiksen, M, Mose, T, Rytting, E, Poulsen, M S, Nielsen, J K S & Knudsen, L E 2014, ' Modelling of Human Transplacental Transport as Performed in Copenhagen, Denmark ', Basic & Clinical Pharmacology & Toxicology, vol. 115, no. 1, pp. 93-100 . https://doi.org/10.1111/bcpt.12228
Mathiesen, L, Morck, T A, Zuri, G, Andersen, M H, Pehrson, C, Frederiksen, M, Mose, T, Rytting, E, Poulsen, M S, Nielsen, J K S & Knudsen, L E 2014, ' Modelling of Human Transplacental Transport as Performed in Copenhagen, Denmark ', Basic & Clinical Pharmacology & Toxicology, vol. 115, no. 1, pp. 93-100 . https://doi.org/10.1111/bcpt.12228
Placenta perfusion models are very effective when studying the placental mechanisms in order to extrapolate to real-life situations. The models are most often used to investigate the transport of substances between mother and foetus, including the po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dde724e6a549589aac9107b4cd26cbb
https://vbn.aau.dk/da/publications/25d9ca6f-06ca-4b5c-b9da-a49ebc2c710b
https://vbn.aau.dk/da/publications/25d9ca6f-06ca-4b5c-b9da-a49ebc2c710b