Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Plaboni Sen"'
Autor:
Plaboni Sen, Siddhartha Sankar Ghosh
Publikováno v:
ACS Pharmacology & Translational Science. 6:651-670
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bbd864a0290d81f493197da3a13c8ce
https://doi.org/10.1021/acsptsci.2c00239
https://doi.org/10.1021/acsptsci.2c00239
WIF1 (Wnt inhibitory factor 1) is a potent tumour suppressor gene which is epigenetically silenced in numerous malignancies. The associations of WIF1 protein with the Wnt pathway molecules have not been fully explored, despite their involvement in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138487be831b58f5854cb4000dd0e2b5
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:11771-11786
Lack of effective targeted therapies often contributes to poor clinical outcomes of aggressive malignancies associated with drug resistance, angiogenesis and metastasis. Literature mining portrays the major role of ADAM17 in cancer and inflammatory d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12221d5aec32f07cf63503a9e085b118
https://doi.org/10.1080/07391102.2021.1964602
https://doi.org/10.1080/07391102.2021.1964602
Autor:
Subhasis Dey, Plaboni Sen, Anjali Patel, Biswa Mohan Prusty, Siddhartha Sankar Ghosh, Debasis Manna
Publikováno v:
Organicbiomolecular chemistry. 20(39)
Multifunctional drug delivery systems are the centerpiece of effective chemotherapeutic strategies. Herein, we report the synthesis of an acetazolamide-linked cyanine-3-based NIR-responsive fluorescent macrocyclic amphiphile that self-assembled into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2279d9be3a152bfcef02688d53e5989d
https://pubmed.ncbi.nlm.nih.gov/36156635
https://pubmed.ncbi.nlm.nih.gov/36156635
Publikováno v:
Cellular signalling. 102
The aberrant expression of the Notch signalling pathway genes aids in potentiating the belligerent characteristics of numerous malignancies. Besides imparting abnormal proliferation and metastasis, the Notch also aids in the metabolic reprogramming o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d98adaa89619954f4eb40ef00ea4e21
https://pubmed.ncbi.nlm.nih.gov/36423860
https://pubmed.ncbi.nlm.nih.gov/36423860
Purpose: The prevalence of cells with mesenchymal features is one of the well-known characteristics of triple negative breast cancers (TNBCs); where cells have undergone epithelial to mesenchymal transition (EMT) and are found to be poorly differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a8fbd9bd1f3a3daee489daa1c10df78
https://doi.org/10.21203/rs.3.rs-1630401/v1
https://doi.org/10.21203/rs.3.rs-1630401/v1
Publikováno v:
Materials Advances. 1:2614-2630
Metastasis is the cause of approximately 90% of cancer-related morbidities and mortalities, which is ascribed to the phenomenon of EMT (epithelial to mesenchymal transition). The pathological activation of EMT during tumour development results in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5502b718b0e5a2a92a8718fd340be64c
https://doi.org/10.1039/d0ma00455c
https://doi.org/10.1039/d0ma00455c
Publikováno v:
Molecular diversity.
Governing protein-protein interaction networks are the cynosure of cell signaling and oncogenic networks. Multifarious processes when aligned with one another can result in a dysregulated output which can result in cancer progression. In the current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2877193ca77f0efc54e0abca0c595144
https://pubmed.ncbi.nlm.nih.gov/35648249
https://pubmed.ncbi.nlm.nih.gov/35648249
Publikováno v:
Molecular informaticsReferences. 41(8)
The present study focuses on the interconnected functional network of altered metabolism and EMT (epithelial to mesenchymal transition) signaling in breast cancer. We have interlinked the metabolic and EMT signaling circuits and selected Insulin rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::552771046331557c80d08697a643e6d5
https://pubmed.ncbi.nlm.nih.gov/35195941
https://pubmed.ncbi.nlm.nih.gov/35195941
Publikováno v:
Journal of Molecular Graphics and Modelling. 115:108225
Cancer malignancies require the application of advanced strategies leading to the development of novel theranostic. Quite often drugs target a variety of receptors in the cell signaling cascades that could be explored to combat aggressive tumors. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77446256006b3bdc03715b6eafae8d9f
https://doi.org/10.1016/j.jmgm.2022.108225
https://doi.org/10.1016/j.jmgm.2022.108225