Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Piyush M. Vyas"'
Publikováno v:
Interspeech 2021.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f586fa53854bb858a6d341b88ae4f55
https://doi.org/10.21437/interspeech.2021-2007
https://doi.org/10.21437/interspeech.2021-2007
Publikováno v:
ICASSP
Speech assessment is crucial for many applications, but current intrusive methods cannot be used in real environments. Data-driven approaches have been proposed, but they use simulated speech materials or only estimate objective scores. In this paper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c9fb0db13273c534c0ae46314c6b11
https://doi.org/10.1109/icassp39728.2021.9414182
https://doi.org/10.1109/icassp39728.2021.9414182
Autor:
Sanjoy Roychowdhury, Piyush M. Vyas, Sharon K. Krueger, William M. Nauseef, Craig K. Svensson, Sevasti B. Koukouritaki, Ronald N. Hines, David E. Williams
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 319:497-505
Arylamine compounds, such as sulfamethoxazole (SMX) and dapsone (DDS), are metabolized in epidermal keratinocytes to arylhydroxylamine metabolites that auto-oxidize to arylnitroso derivatives, which in turn bind to cellular proteins and can act as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f5c28d247be47d78d145b3b8a2c937
https://doi.org/10.1124/jpet.106.105874
https://doi.org/10.1124/jpet.106.105874
Autor:
Farah D. Khan, Radita Nemes, Sanjoy Roychowdhury, Patrick M. Woster, Piyush M. Vyas, Craig K. Svensson
Publikováno v:
Toxicology. 218:90-99
Sulphonamides, such as sulphamethoxazole (SMX) and the related sulphone dapsone (DDS), show a higher incidence of cutaneous drug reactions (CDRs) in patients with the acquired immunodeficiency syndrome (AIDS) compared with human immunodeficiency viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc25ea8883814f9d7acded3c11f7981
https://doi.org/10.1016/j.tox.2005.10.002
https://doi.org/10.1016/j.tox.2005.10.002
Publikováno v:
Drug Metabolism and Disposition. 34:16-18
Sulfamethoxazole (SMX) and dapsone (4,4'-diaminodiphenylsulfone, DDS) are believed to mediate their adverse effects subsequent to bioactivation to their respective arylhydroxylamine and arylnitroso metabolites, resulting in covalent adduct formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6dda0831f4444f1fce757a7550e8135
https://doi.org/10.1124/dmd.105.006890
https://doi.org/10.1124/dmd.105.006890
Autor:
Qiujuan Wang, Wendy J. Tomamichel, R. Mark Payne, Jennifer Mercier, Piyush M. Vyas, E. Martin, P. Melanie Pride, Clifford M. Babbey
Friedreich’s ataxia (FRDA) is the most common inherited human ataxia and results from a deficiency of the mitochondrial protein, frataxin (FXN), which is encoded in the nucleus. This deficiency is associated with an iron–sulfur (Fe–S) cluster e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae808c077e001634bf4637b865e28e25
https://europepmc.org/articles/PMC3284115/
https://europepmc.org/articles/PMC3284115/
Autor:
Piyush M. Vyas, Ronald M Payne
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 16(4)
Mitochondria are complex organelles that perform many key activities in the cell. They contain multiple copies of their own genome, which encodes 13 proteins in humans and the transfer RNAs and ribosomal RNAs needed to translate them.1 Thus, almost a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4277d28ef04db463b9f4f84fbb6d7465
https://pubmed.ncbi.nlm.nih.gov/18362926
https://pubmed.ncbi.nlm.nih.gov/18362926
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 323(3)
The initiation of an immune response to small molecules is believed to require the release of stress/danger signals that activate resident dendritic cells, presumably secondary to the formation of reactive metabolites. We hypothesized that exposure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dec85dc7b20fc0a178334558872da44
https://pubmed.ncbi.nlm.nih.gov/17766678
https://pubmed.ncbi.nlm.nih.gov/17766678
Autor:
Sanjoy Roychowdhury, Piyush M. Vyas, Jatinder K. Lamba, Thomas E. Prisinzano, Joyce Blaisdell, Erin G. Schuetz, Craig K. Svensson, Ronald N. Hines, Joyce A. Goldstein, Kimber L. Munson, Farah D. Khan
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 319(1)
Cutaneous drug reactions (CDRs) are among the most common adverse drug reactions and are responsible for numerous minor to life-threatening complications. Several arylamine drugs, such as sulfamethoxazole (SMX) and dapsone (DDS), undergo bioactivatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f5f49b13c9df1de2c07d8687dda812
https://pubmed.ncbi.nlm.nih.gov/16857728
https://pubmed.ncbi.nlm.nih.gov/16857728
Autor:
Craig K. Svensson, Mark A. Doll, David W. Hein, Payal Bhaiya, Piyush M. Vyas, Sanjoy Roychowdhury
Publikováno v:
Toxicology and applied pharmacology. 215(2)
Cutaneous drug reactions (CDRs) associated with sulfonamides are believed to be mediated through the formation of reactive metabolites that result in cellular toxicity and protein haptenation. We evaluated the bioactivation and toxicity of sulfametho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c0dd3b0dd5c5982dba27e88e30e07f
https://pubmed.ncbi.nlm.nih.gov/16603214
https://pubmed.ncbi.nlm.nih.gov/16603214