Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Piyush K Jain"'
Autor:
Yiran Shen, Bhuwan Khatri, Santosh Rananaware, Danmeng Li, David A Ostrov, Piyush K Jain, Christopher J Lessard, Cuong Q Nguyen
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0276700 (2023)
COVID-19 is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). The severity of COVID-19 is highly variable and related to known (e.g., age, obesity, immune deficiency) and unknown risk factors. The widespread clinical symptoms en
Externí odkaz:
https://doaj.org/article/04b5c4c581934edb9ab6936c6ca5c5b7
Autor:
Xiaojun Wei, Xiaoqin Wang, Zehui Zhang, Yuanyuan Luo, Zixin Wang, Wen Xiong, Piyush K. Jain, John R. Monnier, Hui Wang, Tony Y. Hu, Chuanbing Tang, Helmut Albrecht, Chang Liu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Accurate detection of antigen p24 for HIV−1 early diagnosis remains challenging. Here the authors present a click chemistry amplified nanopore (CAN) assay that allows p24 quantification at ultralow concentration range in clinical samples.
Externí odkaz:
https://doaj.org/article/a53cd8defb0a4df3886cc8a157c25efb
Autor:
Long T. Nguyen, Santosh R. Rananaware, Brianna L. M. Pizzano, Brandon T. Stone, Piyush K. Jain
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-11 (2022)
Plain language summary The COVID-19 pandemic has underscored the need for rapid and accurate tests to detect SARS-CoV-2 infection. The tests commonly used have limitations, and a detection system based on CRISPR technology could offer a useful altern
Externí odkaz:
https://doaj.org/article/ea3c4f546f934a2d92d93cf972ee9314
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
CRISPR-Cas12a based detection systems can be sensitive down to the picomolar range. Here the authors modify the 3′- and 5′-ends of the crRNA and show this enhances trans-cleavage for improved sensitivity.
Externí odkaz:
https://doaj.org/article/de5c4909e62841dd937390825877c68b
Autor:
Long T. Nguyen, Nicolas C. Macaluso, Brianna L.M. Pizzano, Melanie N. Cash, Jan Spacek, Jan Karasek, Megan R. Miller, John A. Lednicky, Rhoel R. Dinglasan, Marco Salemi, Piyush K. Jain
Publikováno v:
EBioMedicine, Vol 77, Iss , Pp 103926- (2022)
Summary: Background: Current SARS-CoV-2 detection platforms lack the ability to differentiate among variants of concern (VOCs) in an efficient manner. CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated) based dete
Externí odkaz:
https://doaj.org/article/a18b5fd53c4f44029ae374b24230bf7a
Autor:
Pathour R. Shashank, Brandon M. Parker, Santosh R. Rananaware, David Plotkin, Christian Couch, Lilia G. Yang, Long T. Nguyen, N. R. Prasannakumar, W. Evan Braswell, Piyush K. Jain, Akito Y. Kawahara
Publikováno v:
bioRxiv
Rapid identification of organisms is essential across many biological and medical disciplines, from understanding basic ecosystem processes and how organisms respond to environmental change, to disease diagnosis and detection of invasive pests. CRISP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfff3a7d50d437a02e54075d576b689
https://doi.org/10.1101/2023.05.16.541004
https://doi.org/10.1101/2023.05.16.541004
Autor:
Santosh R. Rananaware, Emma K. Vesco, Grace M. Shoemaker, Swapnil S. Anekar, Luke Samuel W. Sandoval, Katelyn S. Meister, Nicolas C. Macaluso, Long T. Nguyen, Piyush K. Jain
CRISPR is a prominent bioengineering tool and the type V CRISPR-associated protein complex, Cas12a, is widely used in diagnostic platforms due to its innate ability to cleave DNA substrates. Here we demonstrate that Cas12a can also be programmed to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b35d0822dbbb3d737fead389cafc4e6
https://doi.org/10.1101/2023.01.29.525716
https://doi.org/10.1101/2023.01.29.525716
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20117-z
Externí odkaz:
https://doaj.org/article/fd8478c6f5db4766997805b36a0b1d9d
Autor:
Yiran Shen, Bhuwan Khatri, Santosh Rananaware, Danmeng Li, David A. Ostrov, Piyush K. Jain, Christopher J. Lessard, Cuong Q. Nguyen
COVID-19 is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). The severity of COVID-19 is highly variable and related to known (e.g., age, obesity, immune deficiency) and unknown risk factors. The widespread clinical symptoms en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8092107f01943bd75ffa7da96962da5f
https://doi.org/10.1101/2022.03.30.486345
https://doi.org/10.1101/2022.03.30.486345
Autor:
Chan-Wen Chiu, Minghan Xian, Jenna L. Stephany, Xinyi Xia, Chao-Ching Chiang, Fan Ren, Cheng-Tse Tsai, Siang-Sin Shan, Yu-Te Liao, Josephine F. Esquivel-Upshaw, Santosh R. Rananaware, Long T. Nguyen, Nicolas C. Macaluso, Piyush K. Jain, Melanie N. Cash, Carla N. Mavian, Marco Salemi, Marino E. Leon, Chin-Wei Chang, Jenshan Lin, Stephen J. Pearton
Publikováno v:
J Vac Sci Technol B Nanotechnol Microelectron
The SARS-CoV-2 pandemic has had a significant impact worldwide. Currently, the most common detection methods for the virus are polymerase chain reaction (PCR) and lateral flow tests. PCR takes more than an hour to obtain the results and lateral flow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390e4833665d5af909e7c0195f2a575e
https://europepmc.org/articles/PMC8830941/
https://europepmc.org/articles/PMC8830941/