Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Piyush Gondaliya"'
Publikováno v:
Nanomaterials, Vol 14, Iss 21, p 1727 (2024)
Aptamers are short DNA or RNA sequences that adopt 3D structures and can bind to protein targets with high binding affinity and specificity. Aptamers exhibit excellent tissue penetration, are inexpensive to produce, and can be internalized by cells.
Externí odkaz:
https://doaj.org/article/002aac8706924d29aa1181ed0afdf6fe
Publikováno v:
Hepatology Communications, Vol 8, Iss 3 (2024)
Background:. Impaired natural killer (NK) cell-mediated antitumor responses contribute to the growth of liver tumors. Expression of a disintegrin and metalloprotease 9 (ADAM9) increases shedding of membrane-bound major histocompatibility complex clas
Externí odkaz:
https://doaj.org/article/ba814bc279574e57862677c40449c2e1
Autor:
Adil Ali Sayyed, Piyush Gondaliya, Irene K. Yan, James Carrington, Julia Driscoll, Anuradha Moirangthem, Tushar Patel
Publikováno v:
Nanomaterials, Vol 13, Iss 20, p 2751 (2023)
Extracellular vesicles (EVs) show promise for targeted drug delivery but face production challenges with low yields. Cell-derived nanovesicles (CDNVs) made by reconstituting cell membranes could serve as EV substitutes. In this study, CDNVs were gene
Externí odkaz:
https://doaj.org/article/0d0f651b3b944b078649dc71c7b637d9
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 109, Iss , Pp 1610-1619 (2019)
RhoA/Rho-associated coiled-coil forming protein serine/threonine kinase (ROCK) has appeared as a potential therapeutic target in numerous diseases, because of its preventing action on various enzymes providing antioxidant and cytoprotective action. P
Externí odkaz:
https://doaj.org/article/9d33c809011c44109d9796a3088bb13c
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211591 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0208044.].
Externí odkaz:
https://doaj.org/article/6576a46f7f1945c4893d31179aa0d70b
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0208044 (2018)
The role of DNA methylation has not been enough explored in pathophysiology of diabetic nephropathy (DN). However, according to recent reports it has been inferred that hypermethylation could be one of the principle cause associated with the enhancem
Externí odkaz:
https://doaj.org/article/c4cfbc7b428745d5a0b8792f08aff006
Publikováno v:
Journal of Diabetes & Metabolic Disorders.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0bc08ce57e9b088dd9675ea9f7d3cdc
https://doi.org/10.1007/s40200-023-01208-2
https://doi.org/10.1007/s40200-023-01208-2
Publikováno v:
Molecular Biology Reports. 49:6987-6996
Specificity protein 1 (SP1) was found to play a critical role in the regulation of TGF-β1 driven epithelial-mesenchymal transition (EMT). Recent clinical findings demonstrated a significant drop in the expression of miR-128-3p with the cancer progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675bf57d7fce35e73a67498e1b11be60
https://doi.org/10.1007/s11033-022-07466-2
https://doi.org/10.1007/s11033-022-07466-2
Autor:
Piyush Gondaliya, Adil Ali Sayyed, Palak Bhat, Mukund Mali, Neha Arya, Amit Khairnar, Kiran Kalia
Publikováno v:
Molecular Pharmaceutics. 19:1294-1308
Diabetic wounds are one of the debilitating complications that affect up to 20% of diabetic patients. Despite the advent of extensive therapies, the recovery rate is unsatisfactory, and approximately, 25% of patients undergo amputation, thereby deman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298b9f73e6704b95a69bb96fc6f51908
https://doi.org/10.1021/acs.molpharmaceut.1c00669
https://doi.org/10.1021/acs.molpharmaceut.1c00669
Autor:
Neha Arya, Mukund Mali, Amit Khairnar, Adil Ali Sayyed, Palak Bhat, Kiran Kalia, Piyush Gondaliya
Publikováno v:
Current Pharmaceutical Design. 28:471-487
The discovery of microRNAs (miRNAs) has been one of the revolutionary developments and has led to the advent of new diagnostic and therapeutic opportunities for the management of cancer. In this regard, miRNA dysregulation has been shown to play a cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d43f25f3630f49565ea92ce107157ed6
https://doi.org/10.2174/1381612827666211109113305
https://doi.org/10.2174/1381612827666211109113305