Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Piyush Borole"'
Autor:
Piyush Borole, Ajitha Rajan
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract The ability to predict whether a peptide will get presented on Major Histocompatibility Complex (MHC) class I molecules has profound implications in designing vaccines. Numerous deep learning-based predictors for peptide presentation on MHC
Externí odkaz:
https://doaj.org/article/12b7b2757e484cf6a8c026c261cd1c1d
Autor:
Hyeree Choi, Sagar B. Kudchodkar, Emma L. Reuschel, Kanika Asija, Piyush Borole, Sangya Agarwal, Lucas Van Gorder, Charles C. Reed, Gayathri Gulendran, Stephanie Ramos, Kate E. Broderick, J Joseph Kim, Kenneth E. Ugen, Gary Kobinger, Don L. Siegel, David B. Weiner, Kar Muthumani
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 4, Pp 907-918 (2020)
Significant concerns have arisen over the past 3 y from the increased global spread of the mosquito-borne flavivirus, Zika. Accompanying this spread has been an increase in cases of the devastating birth defect microcephaly as well as of Guillain–B
Externí odkaz:
https://doaj.org/article/4c5462e0a3344f308a609dd19930347f
Autor:
Hyeree Choi, Sagar B Kudchodkar, Emma L Reuschel, Kanika Asija, Piyush Borole, Michelle Ho, Krzysztof Wojtak, Charles Reed, Stephanie Ramos, Nathen E Bopp, Patricia V Aguilar, Scott C Weaver, J Joseph Kim, Laurent Humeau, Pablo Tebas, David B Weiner, Kar Muthumani
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007042 (2019)
Mayaro virus (MAYV) of the genus alphavirus is a mosquito-transmitted emerging infectious disease that causes an acute febrile illness, rash, headaches, and nausea that may turn into incapacitating, persistent arthralgias in some victims. Since its d
Externí odkaz:
https://doaj.org/article/365111ea733342ab82ae66dc7897d8a4
Autor:
Piyush Borole, Ajitha Rajan
The ability to predict whether a peptide will get presented on Major Histocompatibility Complex (MHC) class I molecules has profound implications in designing vaccines. Numerous deep learning-based predictors for peptide presentation on MHC class I m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3c1878db608e7c8d300a46c73876d6
https://doi.org/10.21203/rs.3.rs-2885823/v1
https://doi.org/10.21203/rs.3.rs-2885823/v1
Autor:
Gayathri Gulendran, David B. Weiner, Charles C. Reed, Sagar B. Kudchodkar, Kanika Asija, Hyeree Choi, Karuppiah Muthumani, Lucas Van Gorder, Sangya Agarwal, Piyush Borole, Don L. Siegel, Emma L. Reuschel, J. Joseph Kim, Stephanie Ramos, Kenneth E. Ugen, Gary P. Kobinger, Kate E. Broderick
Publikováno v:
Human Vaccines & Immunotherapeutics
Significant concerns have arisen over the past 3 y from the increased global spread of the mosquito-borne flavivirus, Zika. Accompanying this spread has been an increase in cases of the devastating birth defect microcephaly as well as of Guillain–B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee49c14e8e6becbdc77a8b66a18d0ac5
https://doi.org/10.1080/21645515.2019.1688038
https://doi.org/10.1080/21645515.2019.1688038
In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus
Autor:
Ghiabe Guibinga, Janess M. Mendoza, David B. Weiner, Laurent Humeau, Stephanie Ramos, Jian Yan, Sagar B. Kudchodkar, Trevor R.F. Smith, Kanika Asija, Jeffrey W. Allen, Piyush Borole, Jing Chen, Martina Beltramello, Ami Patel, Mamadou A. Bah, Karin Stettler, Davide Corti, Rianne Esquivel, Amy C. Durham, Hyeree Choi, Daniel H. Park, Shareef Shaheen, Kate E. Broderick, Karuppiah Muthumani
Publikováno v:
Molecular Therapy
Zika virus (ZIKV) infection is endemic to several world regions, and many others are at high risk for seasonal outbreaks. Synthetic DNA-encoded monoclonal antibody (DMAb) is an approach that enables in vivo delivery of highly potent mAbs to control i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133a453f4a05cc225e8fa2a84bcc76ca
https://doi.org/10.1016/j.ymthe.2019.03.005
https://doi.org/10.1016/j.ymthe.2019.03.005
Publikováno v:
GECCO Companion
Rule-based machine learning (RBML) algorithms such as learning classifier systems (LCS) are well suited to classification problems with complex interactions and heterogeneous associations. Alternatively, genetic programming (GP) has a complementary s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::491aa6afbc784f5954415cd1c7b6095e
https://doi.org/10.1145/3377929.3390071
https://doi.org/10.1145/3377929.3390071
Autor:
Konrad P. Kording, David Issadore, Tony Liu, Hanfei Shen, Piyush Borole, Ari S. Benjamin, Jesse Cui
Publikováno v:
Lab on a chip. 20(12)
Liquid biopsy (LB) technologies continue to improve in sensitivity, specificity, and multiplexing and can measure an ever growing library of disease biomarkers. However, clinical interpretation of the increasingly large sets of data these technologie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaffb2bfe503d8f25a576fd768a154b2
https://pubmed.ncbi.nlm.nih.gov/32420563
https://pubmed.ncbi.nlm.nih.gov/32420563
Autor:
Rebecca S. Rivard, Benjamin A. Garcia, Katarzyna Kulej, Veena Jagannathan, Ya‐Chu Yeng, Theonie Anastassiadis, Anja‐Katrin Belinsky, Piyush Borole, Eric J. Brown, Nishita Shastri, Rahul Mandal
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34431e1d15962a5a17b691e371a575c9
https://doi.org/10.1096/fasebj.2019.33.1_supplement.345.2
https://doi.org/10.1096/fasebj.2019.33.1_supplement.345.2
Autor:
Nishita Shastri, Jonathan Schug, Yu Chen Tsai, Piyush Borole, Sharvin Shah, Dillon Maloney, Yancy Lo, Taehyong Kim, Kevin D. Smith, Eric J. Brown, Theonie Anastassiadis, Kanika Asija, Suzanne E. Hile, Barrett M. Powell, Deondre Jordan, Xiang Wang, Liliya A. Yatsunyk, Marei Dose, Kristin A. Eckert, Darren Finn, Osvaldo D. Rivera, Jessica Chen, Rafael Casellas
DNA polymerase stalling activates the ATR checkpoint kinase, which in turn suppresses fork collapse and breakage. Herein, we describe use of ATR inhibition (ATRi) as a means to identify genomic sites of problematic DNA replication in murine and human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dac3cca72941da07835b0650a04a1ae
https://europepmc.org/articles/PMC6407864/
https://europepmc.org/articles/PMC6407864/