Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Pixu Li"'
Autor:
Junhui Yang, Yunjie Zhang, Yifan Kong, Jiawei Lin, Guoqing Zhu, Hao Zhang, Zhijie Yu, Pixu Liu, Jinglin Xia
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 57 (2024)
Transarterial chemoembolization (TACE) is an established therapeutic strategy for intermediate stage Barcelona Clinic Liver Cancer (BCLC) hepatocellular carcinoma (HCC). However, patients who are early refractory to TACE may not benefit from repeated
Externí odkaz:
https://doaj.org/article/58f978e2480649a1ba5bbffc5bd879a3
Autor:
Xiang Gao, Haolin Zhao, Jiao Liu, Min Wang, Zhihong Dai, Wenjun Hao, Yanlong Wang, Xiang Wang, Min Zhang, Pixu Liu, Hailing Cheng, Zhiyu Liu
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Despite the initial efficacy of enzalutamide in castration‐resistant prostate cancer (CRPC), inevitable resistance remains a significant challenge. Here, the synergistic induction of copper‐dependent cell death (cuproptosis) in CRPC cell
Externí odkaz:
https://doaj.org/article/febbb203e9aa4735a6e1ac2e1ad2be88
Autor:
Qing Shi, Yuhan Xia, Minmin Wu, Yating Pan, Shiyi Wu, Jiawei Lin, Yifan Kong, Zhijie Yu, Xingjie Zan, Pixu Liu, Jinglin Xia
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 100958- (2024)
Cirrhosis is an aggressive disease, and over 80 % of liver cancer patients are complicated by cirrhosis, which lacks effective therapies. Transplantation of mesenchymal stem cells (MSCs) is a promising option for treating liver cirrhosis. However, th
Externí odkaz:
https://doaj.org/article/a2fa3ba933774469aee9a62e7dda85a0
Autor:
Schäfer, Gabriel, Fleischer, Tony, Blumer, Nicole, Udry, Megan, Reber, Stefan, Stansfield, Ian, Yuanhua Liu, Yan Li, Pixu Li
Publikováno v:
Organic Process Research & Development; 2/18/2022, Vol. 26 Issue 2, p347-357, 11p
Publikováno v:
Tetrahedron Letters. 57:2273-2276
A visible-light-promoted functionalization of unactivated benzylic sp3 C–H bonds was developed. Ethylbenzene derivatives were converted to the corresponding benzyl bromides or afforded benzylamine derivatives in a one-pot manner under visible light
Autor:
Min Wang, Jiannan Liu, Xingming Liao, Yasong Yi, Yijue Xue, Ling Yang, Hailing Cheng, Pixu Liu
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102931- (2023)
Cancer cells frequently exhibit aberrant redox homeostasis and adaptation to oxidative stress. Hence abrogation of redox adaptation in cancer cells can be exploited for therapeutic benefit. Here we report SGK3 functions as an anti-oxidative factor to
Externí odkaz:
https://doaj.org/article/ae745aed3646417c8644e9b3c4873c93
Autor:
Pixu Li, Weigang Fan
Publikováno v:
Angewandte Chemie International Edition. 53:12201-12204
Secondary enaminones were oxidized by photochemically generated singlet oxygen, followed by nucleophilic addition of alcohol and an unexpected 1,2-acyl migration to afford quaternary amino acid derivatives. An ene-type reaction pathway is proposed. I
Publikováno v:
ACS Catalysis. 4:1897-1900
An aerobic visible-light-promoted indole C-3 formylation reaction catalyzed by Rose Bengal has been developed. This transition-metal-free process employs molecular oxygen as the terminal oxidant and uses TMEDA as the one-carbon source through C–N b
Publikováno v:
Chinese Journal of Chemistry. 32:117-122
A homogeneous visible light photoredox TEMPO-mediated selective oxidation of primary alcohols to the corresponding carbonyl compounds was developed using molecular oxygen from air as the terminal oxidant. Ru(bpy)3(PF6)2 (bpy: bipyridyl) and Ir(dtb-bp
Publikováno v:
Organic Letters. 15:5646-5649
A visible-light photoredox synthesis of α-amino amide or α-amino thioamide from N,N-dimethylaniline derivatives and aryl isocyanate or aryl isothiocyanate was developed. Bis[2-(4,6-difluorophenyl)pyridinato-C(2),N](picolinato)iridium(III) (FIrpic)