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LB1578 Identification and characterization of highly optimized RORγ inverse agonists for the topical treatment of psoriasis

Autor: Hervouet, C., Bihl, F., Ouvry, G., Musicki, B., Harris, C., Bouix-peter, C., Pascau, J., Chaussade, C., Piwnica, D., Deret, S., Julia, V., Hennequin, L., Vial, E., Hacini-Rachinel, F.

Publikováno v: In Journal of Investigative Dermatology September 2018 138(9):B19-B19

Structure-based identification of non-competitive ligands for two related class B G Protein-Coupled receptors

Autor: de Graaf, C., Rein, C, Giordanetto, F, Piwnica, D, Rognan, D.

Publikováno v: ChemMedChem, 6, 2159-2169. John Wiley and Sons Ltd
de Graaf, C, Rein, C, Giordanetto, F, Piwnica, D & Rognan, D 2011, ' Structure-based identification of non-competitive ligands for two related class B G Protein-Coupled receptors ', ChemMedChem, vol. 6, pp. 2159-2169 . https://doi.org/10.1002/cmdc.201100317

Despite the availability of X-ray crystal structure data for several members of the G-protein-coupled receptor (GPCR) superfamily, structure-based discovery of GPCR ligands has been exclusively restricted to classA (rhodopsin-like) receptors. Herein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3bdf8f38b86d0ca397a68873a9f78f0e
https://research.vu.nl/en/publications/5f4a63f6-eaa9-4fe3-a92d-3290ef63ecfc

348 Topical RORγ inverse agonist alleviate preclinical models of psoriasis

Autor: Hervouet, C., Bihl, F., Ouvry, G., Bouix-Peter, C., Chaussade, C., Piwnica, D., Julia, V., Hennequin, L., Vial, E., Hacini-Rachinel, F.

Publikováno v: In Journal of Investigative Dermatology October 2017 137(10) Supplement 2:S252-S252

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