Molecular mechanism of activation and nuclear translocation of the mineralocorticoid receptor upon binding of pregnanesteroids

Autor: Galigniana, M.D, Piwien Pilipuk, G, Kanelakis, K.C, Burton, G, Lantos, C.P

Publikováno v: In Molecular and Cellular Endocrinology 2004 217(1):167-179

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against oxidative stress

Autor: Gallo, L.I., Lagadari, M., Piwien-Pilipuk, G., Galigniana, M.D.

Publikováno v: J. Biol. Chem. 2011;286(34):30152-30160
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN

Confocal microscopy images revealed that the tetratricopeptide repeat motif (TPR) domain immunophilin FKBP51 shows colocalization with the specific mitochondrial marker Mito-Tracker. Signal specificity was tested with different antibodies and by FKBP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::c5aeb314fb92b0677b22a8237801dcd8

Impairment of mineralocorticoid receptor (MR)-dependent biological response by oxidative stress and aging: Correlation with post-translational modification of MR and decreased ADP-ribosylatable level of elongation factor 2 in kidney cells

Autor: Piwien-Pilipuk, G., Ayala, A., Machado, A., Galigniana, M.D.

Publikováno v: J. Biol. Chem. 2002;277(14):11896-11903
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN

Acute and chronic treatments of mice with the glutathione-depleting agent, L-buthionine-(SR)-sulfoximine (BSO), impaired the mineralocorticoid receptor (MR)-dependent biological response by inhibiting aldosterone binding. This steroid-binding inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::418907fdc92ad8ac06bd43e417bb1be7

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.