Výsledky vyhledávání - "Pituitary Neoplasms* / genetics"

A Common Variant in the CDK8 Gene Is Associated with Sporadic Pituitary Adenomas in the Portuguese Population: a Case-Control Study

Autor: Leonor M. Gaspar, Catarina I. Gonçalves, Fernando Fonseca, Davide Carvalho, Luísa Cortez, Ana Palha, Inês F. Barros, Ema Nobre, João S. Duarte, Cláudia Amaral, Maria J. Bugalho, Olinda Marques, Bernardo D. Pereira, Manuel C. Lemos

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11749

The majority of pituitary adenomas occur in a sporadic context, and in the absence of known genetic predisposition. Three common variants at the NEBL (rs2359536), PCDH15 (rs10763170) and CDK8 (rs17083838) loci were previously associated with sporadic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a95929c799cd20e91b69edc4e25e15
https://hdl.handle.net/10400.17/4404

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Primary glomus tumour of the pituitary gland: diagnostic challenges of a rare and potentially aggressive neoplasm

Autor: Federico Roncaroli, Omar N. Pathmanaban, Jean-Philippe Brouland, Helen Mayers, Rao Gattamaneni, Giulia Cossu, Ibrahim Djoukhadar, Konstantina Karabatsou, Carmine Antonio Donofrio, Patrick Shenjere, Muhammed Murtaza, Marta Pereira, Stefano La Rosa, Boon Leong Quah

Publikováno v: Virchows Archiv, vol. 478, no. 5, pp. 977-984
Quah, B L, Donofrio, C A, La Rosa, S, Brouland, J P, Cossu, G, Djoukhadar, I, Mayers, H, Shenjere, P, Pereira, M, Pathmanaban, O N, Murtaza, M O, Gattamaneni, R, Roncaroli, F & Karabatsou, K 2020, ' Primary glomus tumour of the pituitary gland : diagnostic challenges of a rare and potentially aggressive neoplasm ', Virchows Archiv . https://doi.org/10.1007/s00428-020-02923-4
Virchows Archiv

Primary non-neuroendocrine tumours of the pituitary gland and sella are rare lesions often challenging to diagnose. We describe two cases of clinically aggressive primary glomus tumour of the pituitary gland. The lesions occurred in a 63-year-old mal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a98643ed268be0b2faf860eb53208ea
https://doi.org/10.1007/s00428-020-02923-4

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Gene expression profiling of fast- and slow-growing non-functioning gonadotroph pituitary adenomas

Autor: Arvind Y. M. Sundaram, Camilla Maria Falch, Kjersti Ringvoll Normann, Marianne Andersen, Ivars Silamikelis, Tove Lekva, Nicoleta Cristina Olarescu, Jens Bollerslev, Kristin Astrid Berland Øystese, Alexander Eieland

Publikováno v: Falch, C M, Sundaram, A Y M, Øystese, K A, Normann, K R, Lekva, T, Silamikelis, I, Eieland, A K, Andersen, M S, Bollerslev, J & Olarescu, N C 2018, ' Gene expression profiling of fast-and slow-growing non-functioning gonadotroph pituitary adenomas ', European Journal of Endocrinology, vol. 178, no. 3, pp. 295-307 . https://doi.org/10.1530/EJE-17-0702

ObjectiveReliable biomarkers associated with aggressiveness of non-functioning gonadotroph adenomas (GAs) are lacking. As the growth of tumor remnants is highly variable, molecular markers for growth potential prediction are necessary. We hypothesize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126a05ef8be51edb939b724d5fc8fbb4
https://doi.org/10.1530/eje-17-0702

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Clinical Features of Multiple Endocrine Neoplasia Type 4:Novel Pathogenic Variant and Review of Published Cases

Autor: Pernille Hermann, Charlotte Ejersted, Rajesh V. Thakker, Anja Lisbeth Frederiksen, Maria Rossing, Morten Frost

Publikováno v: Frederiksen, A, Rossing, M, Hermann, P, Ejersted, C, Thakker, R V & Frost, M 2019, ' Clinical Features of Multiple Endocrine Neoplasia Type 4 : Novel Pathogenic Variant and Review of Published Cases ', The Journal of clinical endocrinology and metabolism, vol. 104, no. 9, pp. 3637-3646 . https://doi.org/10.1210/jc.2019-00082
The Journal of Clinical Endocrinology and Metabolism

Context The clinical phenotype of multiple endocrine neoplasia type 4 (MEN4) is undefined due to a limited number of published cases. Knowledge on disease manifestation in MEN4 is essential for developing prevention programs and treatment. Objective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6e694e40c49c3f682b3c5962187dff
https://findresearcher.sdu.dk:8443/ws/files/153078052/Clinical_Features_of_Multiple_Endocrine_Neoplasia_Type_4.pdf

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Elektronická kniha

Oncogenesis and Molecular Biology of Pituitary Tumors

Autor: S. Melmed

This comprehensive volume focuses on mechanisms leading to pituitary tumor formation and progression. The individual chapters provide timely updates on developments in the rapidly expanding field of pituitary tumor pathogenesis. Researchers from lead

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Succinate Dehydrogenase (SDH)-Deficient Pancreatic Neuroendocrine Tumor Expands the SDH-Related Tumor Spectrum

Autor: Jeroen C. Jansen, Nicolasine D. Niemeijer, Frederik J. Hes, Hans Morreau, Thomas G. Papathomas, Ronald R. de Krijger, Esther Korpershoek, Jean-Pierre Bayley, Eleonora P M Corssmit, Winand N.M. Dinjens, Lindsey Oudijk

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 100(10), E1386-E1393. Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 100(10), E1386-E1393
Journal of Clinical Endocrinology and Metabolism, 100(10), E1386. The Endocrine Society

Context: Mutations in genes encoding the subunits of succinate dehydrogenase (SDH) can lead to pheochromocytoma/paraganglioma formation. However, SDH mutations have also been linked to nonparaganglionic tumors. Objective: The objective was to investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de440fea29614a26f474aeb20da7cf68
https://hdl.handle.net/20.500.14017/52a949a6-24c2-441f-b092-d46049b678f2

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