Sharing the Burden: The Case for Definitive Local Therapy in Place of Immune Checkpoint Blockade for Patients With a Low-Volume Burden of Metastatic Disease.

Autor: Lynch C; University of Chicago Medical Center, Department of Radiation and Cellular Oncology, Chicago, IL., Arshad M; University of Chicago Medical Center, Department of Radiation and Cellular Oncology, Chicago, IL., Katipally RR; University of Chicago Medical Center, Department of Radiation and Cellular Oncology, Chicago, IL., Pitroda SP; University of Chicago Medical Center, Department of Radiation and Cellular Oncology, Chicago, IL., Weichselbaum RR; University of Chicago Medical Center, Department of Radiation and Cellular Oncology, Chicago, IL.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Oct 10; Vol. 42 (29), pp. 3387-3391. Date of Electronic Publication: 2024 Jul 22.

Safety of combined ablative radiotherapy and immune checkpoint inhibitors in three phase I trials.

Autor: Lynch C; The University of Chicago Medical Center, Department of Radiation and Cellular Oncology, United States., Korpics MC; The University of Chicago Medical Center, Department of Radiation and Cellular Oncology, United States., Katipally RR; The University of Chicago Medical Center, Department of Radiation and Cellular Oncology, United States., Bestvina CM; The University of Chicago Medical Center, Department of Medical Oncology, United States., Pitroda SP; The University of Chicago Medical Center, Department of Radiation and Cellular Oncology, United States., Patel JD; Northwestern University, Division of Hematology and Oncology, United States., Luke JJ; UPMC Hillman Cancer Center and University of Pittsburgh, United States., Chmura SJ; The University of Chicago Medical Center, Department of Radiation and Cellular Oncology, United States., Juloori A; The University of Chicago Medical Center, Department of Radiation and Cellular Oncology, United States. Electronic address: ajuloori@uchicagomedicine.org.

Publikováno v: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2024 Sep; Vol. 209, pp. 114264. Date of Electronic Publication: 2024 Aug 02.

DARES: A Phase II Trial of Durvalumab and Ablative Radiation in Extensive-Stage Small Cell Lung Cancer.

Autor: Bestvina CM; Department of Medicine, Section of Hematology and Oncology, The University of Chicago Medicine, Chicago, IL., Hara JHL; Department of Radiation Oncology, The Queen's Medical Center, Honolulu, HI., Karrison T; Department of Public Health Sciences, The University of Chicago, Chicago, IL., Bowar B; Department of Pharmacy, University of Chicago Medical Center, Chicago, IL., Chin J; Department of Medicine, Section of Hematology and Oncology, The University of Chicago Medicine, Chicago, IL., Garassino MC; Department of Medicine, Section of Hematology and Oncology, The University of Chicago Medicine, Chicago, IL., Pitroda SP; Department of Radiation and Cellular Oncology, The University of Chicago Medicine, Chicago, IL., Thawani R; Department of Medicine, Section of Hematology and Oncology, The University of Chicago Medicine, Chicago, IL., Vokes EE; Department of Medicine, Section of Hematology and Oncology, The University of Chicago Medicine, Chicago, IL., Gan G; Department of Radiation Oncology, Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS., Zhang J; Department of Internal Medicine, Division of Medical Oncology; Department of Cancer Biology, University of Kansas Medical Center, Kansas City, KS., Baschnagel AM; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, WI., Campbell TC; Department of Medicine, University of Wisconsin-Madison, Madison, WI., Chmura S; Department of Radiation and Cellular Oncology, The University of Chicago Medicine, Chicago, IL., Juloori A; Department of Radiation and Cellular Oncology, The University of Chicago Medicine, Chicago, IL. Electronic address: ajuloori@radonc.uchicago.edu.

Publikováno v: Clinical lung cancer [Clin Lung Cancer] 2024 Aug 13. Date of Electronic Publication: 2024 Aug 13.

Hormonal Therapy and Radiation Therapy in Prostate Cancer: 5-Year Outcomes From a Trial Evaluating Combined Androgen Blockade With 5-Alpha Reductase Inhibitors as an Alternative to Gonadotropin Releasing Hormone Agonists.

Autor: Rajeev-Kumar G; Department of Radiation and Cellular Oncology, University of Chicago, 5758 S. Maryland Ave, Chicago, IL 60637, USA., Pitroda SP; Department of Radiation and Cellular Oncology, University of Chicago, 5758 S. Maryland Ave, Chicago, IL 60637, USA., Szmulewitz RZ; Genitourinary Oncology Program, Department of Medicine, University of Chicago, 5841 S. Maryland Ave, Chicago, IL 60637, USA., Skolarus T; Department of Urology, University of Chicago, 5758 S. Maryland Ave, DCAM 2D, Chicago, IL 60637, USA., Eggener SE; Department of Urology, University of Chicago, 5758 S. Maryland Ave, DCAM 2D, Chicago, IL 60637, USA., Liauw SL; Department of Radiation and Cellular Oncology, University of Chicago, 5758 S. Maryland Ave, Chicago, IL 60637, USA. Electronic address: sliauw@radonc.uchicago.edu.

Publikováno v: Clinical genitourinary cancer [Clin Genitourin Cancer] 2024 Aug; Vol. 22 (4), pp. 102103. Date of Electronic Publication: 2024 Apr 24.

Radiotherapy Enhances Metastasis Through Immune Suppression by Inducing PD-L1 and MDSC in Distal Sites.

Autor: Hou Y; Department of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, ShaanXi, China.; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois., Yang K; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois., Wang L; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois., Wang J; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois., Huang X; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois., Piffkó A; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois., Luo SZ; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois., Yu X; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois., Rao E; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois., Martinez C; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois., Bugno J; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois.; The Committee on Clinical Pharmacology and Pharmacogenomics, University of Chicago, Chicago, Illinois., Mack M; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Vokes EE; Department of Medicine, University of Chicago, Chicago, Illinois., Pitroda SP; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois., Chmura SJ; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois., Weichselbaum RR; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois., Liang HL; Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois.; Ludwig Center for Metastasis Research, University of Chicago, Chicago, Illinois.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 May 01; Vol. 30 (9), pp. 1945-1958.