Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia

Autor: Sekulovski, Samoil, Devant, Pascal, Panizza, Silvia, Gogakos, Tasos, Pitiriciu, Anda, Heitmeier, Katharina, Ramsay, Ewan Phillip, Barth, Marie, Schmidt, Carla, Tuschl, Thomas, Baas, Frank, Weitzer, Stefan, Martinez, Javier, Trowitzsch, Simon

Publikováno v: Nature Communications, 12(1). NATURE PORTFOLIO
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications 12(1), 5610 (2021). doi:10.1038/s41467-021-25870-3
Nature communications, 12(1):5610. Nature Publishing Group

Nature Communications 12(1), 5610 (2021). doi:10.1038/s41467-021-25870-3
Introns of human transfer RNA precursors (pre-tRNAs) are excised by the tRNA splicing endonuclease TSEN in complex with the RNA kinase CLP1. Mutations in TSEN/CLP1 occur in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e93772bdb6060f136d757a51d56332
http://hdl.handle.net/1887/3223105