Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut-liver axis activation

Autor: Porras, D, Nistal, E, Martinez-Florez, S, Pisonero-Vaquero, S, Olcoz, JL, Jover, R, Gonzalez-Gallego, J, Garcia-Mediavilla, MV, Sanchez-Campos, S

Publikováno v: FREE RADICAL BIOLOGY AND MEDICINE
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

60 p. Gut microbiota is involved in obesity, metabolic syndrome and the progression of nonalcoholic fatty liver disease (NAFLD). It has been recently suggested that the flavonoid quercetin may have the ability to modulate the intestinal microbiota co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0aab033bde52e51ae5f44db4fe6ef1d6
http://hdl.handle.net/10612/5686

Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of nonalcoholic fatty liver disease

Autor: Pisonero-Vaquero S, Martínez-Ferreras Á, García-Mediavilla MV, Martínez-Flórez S, Fernández A, Benet M, Olcoz JL, Jover R, González-Gallego J, Sánchez-Campos S

Publikováno v: MOLECULAR NUTRITION & FOOD RESEARCH
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Scope: Flavonoids and related compounds seem to have favorable effects on nonalcoholic fatty liver disease (NAFLD) progression, although the exact mechanisms implicated are poorly understood. In this study, we aimed to investigate the effect of the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::a3b9ce007c64427bb89beabbe02097c3
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=2498

The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARa; and repressed by C/EBPa: Implications in FABP1 down-regulation in nonalcoholic fatty liver disease

Autor: Guzmán C, Benet M, Pisonero-Vaquero S, Moya M, García-Mediavilla MV, Martínez-Chantar ML, González-Gallego J, Castell JV, Sánchez-Campos S, Jover R

Publikováno v: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Liver fatty acid binding protein (FABP1) prevents lipotoxicity of free fatty acids and regulates fatty acid trafficking and partition. Our objective is to investigate the transcription factors controlling the human FABP1 gene and their regulation in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::73bb572f9856500ade0f38bd7adf058a
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=2634

P0973 : Quercetin ameliorates MCD-induced non-alcoholic fatty liver disease in mice by modulating inflammatory, oxidative/nitrosative stress and lipid metabolism-related gene deregulation via the PI3K/AKT pathway

Autor: Pisonero-Vaquero, S., Martínez-Ferreras, Á., García-Mediavilla, M.V., Martínez-Flórez, S., Fernández, A., Benet, M., Olcoz, J.L., Jover, R., González-Gallego, J., Sánchez-Campos, S.

Publikováno v: In Journal of Hepatology April 2015 62 Supplement 2:S711-S711

868 LIVER X RECEPTOR a-MEDIATED LIPOGENESIS INDUCED BY HEPATITIS C VIRUS NS5A AND CORE PROTEINS REGULATES VIRAL REPLICATION IN AN IN VITRO MODEL

Autor: Pisonero-Vaquero, S., García-Mediavilla, M.V., Jorquera, F., Majano, P.L., Gonzalez-Gallego, J., Sánchez-Campos, S.

Publikováno v: In Journal of Hepatology April 2012 56 Supplement 2:S338-S338