Peptide-nucleotide Antibiotic Microcin C Is a Potent Inducer of Stringent Response and Persistence in Both Sensitive and Producing Cells

Autor: Piskunova, Julia, Maisonneuve, Etienne, Germain, Elsa, Gerdes, Kenn, Severinov, Konstantin

Microcin C (McC) is a peptide-nucleotide antibiotic that inhibits aspartyl-tRNA synthetase. Here, we show that McC is a strong inducer of persistence in Escherichia coli. Persistence induced by McC is mediated by (p)ppGpp and requires chromosomally e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::10b70f3a7a9e0ab5f63b05d9c76358cf
https://europepmc.org/articles/PMC6876116/

Expression of genes involved in carbohydrate-lipid metabolism in muscle and fat tissues in the initial stage of adult-age obesity in fed and fasted mice.

Autor: Bazhan NM; Laboratory of Physiological Genetics, The Siberian Branch of the Russian Academy of Sciences, The Federal Research Center Institute of Cytology and Genetics, Novosibirsk, Russia bazhan-nm@yandex.ru., Baklanov AV; Laboratory of Physiological Genetics, The Siberian Branch of the Russian Academy of Sciences, The Federal Research Center Institute of Cytology and Genetics, Novosibirsk, Russia., Piskunova JV; Department of Physiology, Novosibirsk State University, Novosibirsk, Russia., Kazantseva AJ; Laboratory of Physiological Genetics, The Siberian Branch of the Russian Academy of Sciences, The Federal Research Center Institute of Cytology and Genetics, Novosibirsk, Russia., Makarova EN; Laboratory of Physiological Genetics, The Siberian Branch of the Russian Academy of Sciences, The Federal Research Center Institute of Cytology and Genetics, Novosibirsk, Russia.

Publikováno v: Physiological reports [Physiol Rep] 2017 Oct; Vol. 5 (19). Date of Electronic Publication: 2017 Oct 16.