Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Pisanu Buphamalai"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Despite the clear causal relationship between genotype and phenotype in rare diseases, identifying the pathobiological mechanisms at various levels of biological organization remains a practical and conceptual challenge. Here, the authors introduce a
Externí odkaz:
https://doaj.org/article/45ac36fef3284a0c8a60f92f22f0bb0f
Autor:
Jung-Ming G. Lin, Christian Schmidl, Hans Michael Maric, Emilio Casanova, Keiryn L. Bennett, Gerald Hofstaetter, André C. Müller, Johannes Zuber, Robert Kralovics, Anna Ringler, Katja Parapatics, Freya Klepsch, Wanhui You, Karl Mechtler, Matthias Farlik, Jörg Menche, André F. Rendeiro, Stefan Kubicek, Sandra Schick, Bettina Guertl, Sara Sdelci, Kristaps Klavins, Michael Schuster, Herwig P. Moll, Christoph Bock, Thomas Penz, Philipp Rathert, Otto Hudecz, James E. Bradner, Georg E. Winter, Shuang-Yan Wang, Fiorella Schischlik, Peter Májek, Pisanu Buphamalai, Matthew Oldach, Richard Imre, Dennis L. Buckley
Publikováno v:
Nature genetics
Nature Genetics
Nature Genetics
The histone acetyl reader bromodomain-containing protein 4 (BRD4) is an important regulator of chromatin structure and transcription, yet factors modulating its activity have remained elusive. Here we describe two complementary screens for genetic an
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Rare genetic diseases are typically caused by a single gene defect. Despite this clear causal relationship between genotype and phenotype, identifying the pathobiological mechanisms at various levels of biological organization remains a practical and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce28e5b9bda9c36a15b8b6f374936af0
https://hdl.handle.net/11353/10.1597331
https://hdl.handle.net/11353/10.1597331
Publikováno v:
Current Opinion in Systems Biology. 3:88-94
Recent advances in high-throughput technologies have created exciting opportunities for systematically investigating the molecular basis of human disease. In addition to a growing catalog of disease-associated genetic variations, we can now map out a
Autor:
Frank J. Kaiser, Emma Bedoukian, Roberto Nitsch, Georg Christoph Korenke, Bernd Wollnik, Michel K. Herde, Josef M. Penninger, Yun Li, Anoop Kavirayani, Ana Cicvaric, Ronja Hollstein, Paul Moeseneder, Christian Henneberger, Ewelina Lenartowicz, Gökhan Yigit, Vanja Nagy, Tsung-Pin Pai, Matthew A. Deardorff, Francisco Quiroga, E. Ferda Percin, Pisanu Buphamalai, Jörg Menche, Ivona Kozieradzki
Publikováno v:
Neurology / Genetics 5(3), e330 (2019). doi:10.1212/NXG.0000000000000330
Neurology: Genetics
Neurology: Genetics
ObjectiveWe aim to characterize the causality and molecular and functional underpinnings of HACE1 deficiency in a mouse model of a recessive neurodevelopmental syndrome called spastic paraplegia and psychomotor retardation with or without seizures (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4354958f847d8df47dd78439d7e4f3f
http://resolver.sub.uni-goettingen.de/purl?gs-1/16714
http://resolver.sub.uni-goettingen.de/purl?gs-1/16714
Autor:
Peter Májek, Richard Imre, Christian Schmidl, Wanhui You, Pisanu Buphamalai, Fiorella Schischlik, Georg E. Winter, Dennis L. Buckley, Otto Hudecz, Stefan Kubicek, Christoph Bock, Bettina Guertl, James E. Bradner, Anna Ringler, Gerald Hofstaetter, Emilio Casanova, Philipp Rathert, Matthias Farlik, André C. Müller, Michael Schuster, Herwig P. Moll, Johannes Zuber, Robert Kralovics, Sara Sdelci, Thomas Penz, Freya Klepsch, Sandra Schick, Kristaps Klavins, Jörg Menche, Karl Mechtler, Matthew Oldach, Keiryn L. Bennett, André F. Rendeiro, Katja Parapatics
The histone acetyl-reader BRD4 is an important regulator of chromatin structure and transcription, yet factors modulating its activity have remained elusive. Here we describe two complementary screens for genetic and physical interactors of BRD4, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e8ad8b40de774d9f4b21cc367bb5ed
https://doi.org/10.1101/439422
https://doi.org/10.1101/439422
Autor:
Pisanu Buphamalai, Varodom Charoensawan, Patompon Wongtrakoongate, Palatip Chutoam, Apiratana Kum-arth, Sumalee Tungpradabkul
Publikováno v:
Microbiology and Immunology.
Burkholderia pseudomallei, a pathogenic gram-negative bacterium, causes the severe human disease melioidosis. This organism can survive in eukaryotic host cells by escaping reactive oxygen species via the regulation of stress responsive sigma factors
Autor:
Palatip, Chutoam, Varodom, Charoensawan, Patompon, Wongtrakoongate, Apiratana, Kum-Arth, Pisanu, Buphamalai, Sumalee, Tungpradabkul
Publikováno v:
Microbiology and immunology. 57(9)
Burkholderia pseudomallei, a pathogenic gram-negative bacterium, causes the severe human disease melioidosis. This organism can survive in eukaryotic host cells by escaping reactive oxygen species via the regulation of stress responsive sigma factors