Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pirthipal Singh"'
Autor:
Walter Hj Ward, Pirthipal Singh
Publikováno v:
Expert opinion on drug discovery. 3(7)
Background: Many protein kinases are targets for inhibition during drug discovery. Most first generation inhibitors bind at a site used by the purine moiety of ATP and were discovered in assays following inhibition of activated forms of protein kinas
Autor:
Simon M. Poucher, G. Jones, M.G. Collis, J.R. Keddie, Pirthipal Singh, P.W.R. Caulkett, S.M. Stoggall
Publikováno v:
British Journal of Pharmacology. 115:1096-1102
1. This paper describes the in vitro pharmacology of ZM 241385 (4-(2-[7-amino-2-(2-furyl) [1,2,4]-triazolo[2,3-a][1,3,5]triazin- 5-yl amino]ethyl) phenol), a novel non-xanthine adenosine receptor antagonist with selectivity for the A2a receptor subty
Publikováno v:
Assay and drug development technologies. 2(2)
ATP is one of the substrates of luciferase. ATP concentrations can be measured by quantitating the light output from a luciferase reaction. As kinases also use ATP, it is possible to assay kinase activity through the loss of luminescence in a coupled
Publikováno v:
Analytical biochemistry. 222(2)
Akademický článek
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Publikováno v:
Assay & Drug Development Technologies; Apr2004, Vol. 2 Issue 2, p161-169, 9p
Publikováno v:
International Journal of Clinical Practice. 28:307-310
Publikováno v:
Chromatographia; Jun2009, Vol. 69 Issue 11/12, p1489-1491, 3p
Publikováno v:
Chest. 62:339
Recurrent, massive hemoptysis secondary to a migrating foreign body (a Steinman's pin) found embedded in the lung parenchyma, is presented. Prompt surgical intervention helped this patient.
Publikováno v:
Archives of Surgery. 91:646
THE CLINICAL diagnosis of thyroid swellings is not always reliable in spite of the fact that the gland is easily accessible and large numbers of laboratory aids are available. The surgeon, when confronted with a nodule in the thyroid gland, is faced