Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Pirooz, Zareie"'
Autor:
Christopher Szeto, Pirooz Zareie, Rushika C. Wirasinha, Justin B. Zhang, Andrea T. Nguyen, Alan Riboldi-Tunnicliffe, Nicole L. La Gruta, Stephanie Gras, Stephen R. Daley
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Differentiation and activation of T cells are normally modulated by non-covalent interactions between T cell receptor (TCR) and antigenic peptides. Here the authors use step-wise mutations, biochemical characterization and structural insights to desc
Externí odkaz:
https://doaj.org/article/7e92a31da92d45c4ae21ba3f6d5114af
Autor:
Carolina Lliberos, Seng H. Liew, Pirooz Zareie, Nicole L. La Gruta, Ashley Mansell, Karla Hutt
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Reproductive ageing in females is defined by a progressive decline in follicle number and oocyte quality. This is a natural process that leads to the loss of fertility and ovarian function, cycle irregularity and eventually menopause or repr
Externí odkaz:
https://doaj.org/article/ccf2ef3a52fb47d880669b6ed595328e
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-10 (2017)
Abstract Atypical antipsychotic agents, such as clozapine, are used for treating psychosis and depression and have recently been found to modulate neuroinflammation. We have shown previously that treatment of mice with the atypical antipsychotic agen
Externí odkaz:
https://doaj.org/article/583d8c3f8afc465ba09422b80739f64d
Autor:
Amy L. Winship, Lauren R. Alesi, Sneha Sant, Jessica M. Stringer, Aldana Cantavenera, Teharn Hegarty, Carolina Lliberos Requesens, Seng H. Liew, Urooza Sarma, Meaghan J. Griffiths, Nadeen Zerafa, Stephen B. Fox, Emmaline Brown, Franco Caramia, Pirooz Zareie, Nicole L. La Gruta, Kelly-Anne Phillips, Andreas Strasser, Sherene Loi, Karla J. Hutt
Publikováno v:
Nature Cancer. 3:1-13
Loss of fertility is a major concern for female reproductive-age cancer survivors, since a common side-effect of conventional cytotoxic cancer therapies is permanent damage to the ovary. While immunotherapies are increasingly becoming a standard of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f5921ffaf7787f14ee404e6e7845c9f
https://doi.org/10.1038/s43018-022-00413-x
https://doi.org/10.1038/s43018-022-00413-x
Autor:
Seng H. Liew, Carolina Lliberos, Ashley Mansell, Nicole L. La Gruta, Pirooz Zareie, Karla J. Hutt
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Reproductive ageing in females is defined by a progressive decline in follicle number and oocyte quality. This is a natural process that leads to the loss of fertility and ovarian function, cycle irregularity and eventually menopause or reproductive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caec178a5fa24a529091623117df1448
https://doaj.org/article/ccf2ef3a52fb47d880669b6ed595328e
https://doaj.org/article/ccf2ef3a52fb47d880669b6ed595328e
Autor:
Moumita Paul-Heng, Martina Denkova, Eric Taeyoung Son, Thomas Ashhurst, Mario Leong, Claerwen Jones, Pirooz Zareie, Anthony Purcell, Nicole L La Gruta, Nicole Mifsud, Alexandra Sharland
Publikováno v:
Transplantation. 106:S483-S484
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::032b1a584e9d9552e73f976cdf897ba4
https://doi.org/10.1097/01.tp.0000888040.26350.56
https://doi.org/10.1097/01.tp.0000888040.26350.56
Autor:
Ting Wu, Nicole L. La Gruta, Angela Nguyen, Andrea T. Nguyen, Jamie Rossjohn, Anthony W. Purcell, David C. Tscharke, Stephanie Gras, Xavier Y.X. Sng, C. Farenc, Pirooz Zareie, Lisa M Assmus, Nathan P. Croft, Jing Guan, Paul G. Thomas
Publikováno v:
The Journal of Immunology. 205:1731-1742
The presentation of pathogen-derived peptides on MHC class I molecules is essential for the initiation of adaptive CD8+ T cell immunity, which in turn is critical for effective control of many significant human infections. The identification of immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::478dc83fb329817a1a493a5f6c95f77c
https://doi.org/10.4049/jimmunol.2000689
https://doi.org/10.4049/jimmunol.2000689
Autor:
Xavier Y.X. Sng, Claerwen M. Jones, Stephen J. Turner, Stephen R. Daley, Jason K.C. Lee, Pirooz Zareie, Kylie M. Quinn, Lisa M Assmus, Jasmine Li, Nicole L. La Gruta
Publikováno v:
The Journal of Immunology. 204:3108-3116
Naive CD8+ T cell survival in the periphery is critically dependent on tonic TCR signaling through peptide + MHC class I (MHCI) recognition; however, little is known about how natural variation in MHCI levels impacts the naive CD8+ T cell repertoire.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb1f8b5c9d9d89ade82f3b8c51b0d839
https://doi.org/10.4049/jimmunol.2000081
https://doi.org/10.4049/jimmunol.2000081
Publikováno v:
Viral Immunology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8764ad8b12d0b8908bc8dbf8d84754c4
http://europepmc.org/articles/PMC7185327
http://europepmc.org/articles/PMC7185327
Autor:
David O'Sullivan, Laura Green, Sarrabeth Stone, Pirooz Zareie, Marie Kharkrang, Dahna Fong, Bronwen Connor, Anne Camille La Flamme
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104430 (2014)
Recent studies have demonstrated that atypical antipsychotic agents, which are known to antagonize dopamine D2 and serotonin 5-HT2a receptors, have immunomodulatory properties. Given the potential of these drugs to modulate the immune system both per
Externí odkaz:
https://doaj.org/article/6ca2b6f2f94f491a95e6eedb6def3ff2