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pro vyhledávání: '"Pirkko Koelle"'
Autor:
Hua Huang, Pirkko Koelle, Markus Fendler, Angelika Schroettle, Michael Czihal, Ulrich Hoffmann, Peter Jan Kuhlencordt
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114643 (2014)
Niacin reduces vascular oxidative stress and down regulates inducible nitric oxide synthase, an enzyme mediating proatherosclerotic effects in part by increasing oxidative stress. Here, we evaluate whether Niacin reverses the redox sensitive migrator
Externí odkaz:
https://doaj.org/article/9bcd94c9a26847f68dc0775a7b2276ec
Autor:
Markus Fendler, Marcus Conrad, Michael Czihal, Angelika Schröttle, Peter J. Kuhlencordt, Udo Hoffmann, Pirkko Koelle, Hua Huang
Publikováno v:
Atherosclerosis. 235:213-222
Deletion of inducible nitric oxide synthase (iNOS) in apolipoprotein E knockout mice was shown to mitigate the extent of arteriosclerosis. Oxidized low density lipoprotein (oxLDL) inhibits macrophage migration and traps foam cells, possibly through a