Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Pirkko Härkönen"'
Autor:
Syeda Afshan, Yu Gang Kim, Jesse Mattsson, Malin Åkerfelt, Pirkko Härkönen, Martin Baumgartner, Matthias Nees
Publikováno v:
Cancer Medicine, Vol 13, Iss 18, Pp n/a-n/a (2024)
Abstract Background Inhibition of androgen receptor (AR) signaling is the main treatment strategy in advanced prostate cancer (PCa). A subset of castration resistant prostate cancer (CRPC) bypasses the AR blockade by increased fibroblast growth facto
Externí odkaz:
https://doaj.org/article/50bad1de5a494228b47b0e9e0c70543a
Autor:
Joonas Terävä, Alejandra Verhassel, Orsola Botti, Md. Khirul Islam, Janne Leivo, Saara Wittfooth, Pirkko Härkönen, Kim Pettersson, Kamlesh Gidwani
Publikováno v:
Cancer Reports, Vol 5, Iss 8, Pp n/a-n/a (2022)
Abstract Background Breast cancer is a very common cancer that can be severe if not discovered early. The current tools to detect breast cancer need improvement. Cancer has a universal tendency to affect glycosylation. The glycosylation of circulatin
Externí odkaz:
https://doaj.org/article/2cd8c0c80d984699aa505fa5c772e6eb
Autor:
Niina M Santio, Sini K Eerola, Ilkka Paatero, Jari Yli-Kauhaluoma, Fabrice Anizon, Pascale Moreau, Johanna Tuomela, Pirkko Härkönen, Päivi J Koskinen
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130340 (2015)
Pim family proteins are oncogenic kinases implicated in several types of cancer and involved in regulation of cell proliferation, survival as well as motility. Here we have investigated the ability of Pim kinases to promote metastatic growth of prost
Externí odkaz:
https://doaj.org/article/eff7f0a192ff405ebb92c3b015644444
Autor:
Azharuddin Sajid Syed Khaja, Nishtman Dizeyi, Pradeep Kumar Kopparapu, Lola Anagnostaki, Pirkko Härkönen, Jenny Liao Persson
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72210 (2013)
Alterations in cellular pathways related to both endocrine and vascular endothelial growth factors (VEGF) may contribute to breast cancer progression. Inhibition of the elevated levels of these pathways is associated with clinical benefits. However,
Externí odkaz:
https://doaj.org/article/66eccc4ccb5d44319d5b5fe8c33ba847
Publikováno v:
BioTechniques, Vol 28, Iss 5, Pp 832-834 (2000)
Externí odkaz:
https://doaj.org/article/2e08425a3f054c0cbe546251ee1a39b0
Autor:
Tommy Andersson, Pirkko Härkönen, Janna Dejmek, Jeanette Rosenkvist, Johanna Tuomela, Annette Säfholm
Supplementary Data from The Wnt-5a–Derived Hexapeptide Foxy-5 Inhibits Breast Cancer Metastasis In vivo by Targeting Cell Motility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a5a258c6b4d3a0cf05fbeb6e2955d3
https://doi.org/10.1158/1078-0432.22439766.v1
https://doi.org/10.1158/1078-0432.22439766.v1
Autor:
Tommy Andersson, Pirkko Härkönen, Janna Dejmek, Jeanette Rosenkvist, Johanna Tuomela, Annette Säfholm
Purpose: An inherent problem in breast cancer treatment is that current therapeutic approaches fail to specifically target the dissemination of breast cancer cells from the primary tumor. Clinical findings show that the loss of Wnt-5a protein express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47affa81ef6032c36ba4d7538f3b2b2a
https://doi.org/10.1158/1078-0432.c.6517188
https://doi.org/10.1158/1078-0432.c.6517188
Autor:
Stollenwerk, Sarah Beyer, Martha Kimani, Yuecheng Zhang, Alejandra Verhassel, Louise Sternbæk, Tianyan Wang, Jenny L. Persson, Pirkko Härkönen, Emil Johansson, Remi Caraballo, Mikael Elofsson, Kornelia Gawlitza, Knut Rurack, Lars Ohlsson, Zahra El-Schich, Anette Gjörloff Wingren, Maria M.
Publikováno v:
Cancers; Volume 14; Issue 8; Pages: 1875
Sialic acid (SA) is a monosaccharide usually linked to the terminus of glycan chains on the cell surface. It plays a crucial role in many biological processes, and hypersialylation is a common feature in cancer. Lectins are widely used to analyze the
Autor:
Sarah, Beyer, Martha, Kimani, Yuecheng, Zhang, Alejandra, Verhassel, Louise, Sternbæk, Tianyan, Wang, Jenny L, Persson, Pirkko, Härkönen, Emil, Johansson, Remi, Caraballo, Mikael, Elofsson, Kornelia, Gawlitza, Knut, Rurack, Lars, Ohlsson, Zahra, El-Schich, Anette Gjörloff, Wingren, Maria M, Stollenwerk
Publikováno v:
Cancers. 14(8)
Sialic acid (SA) is a monosaccharide usually linked to the terminus of glycan chains on the cell surface. It plays a crucial role in many biological processes, and hypersialylation is a common feature in cancer. Lectins are widely used to analyze the
Autor:
Yu Lan, Päivi J. Koskinen, Niklas Paulin, Sofia Khan, Pirkko Härkönen, Tiina E. Kähkönen, Peter J. Boström, Otto Ettala, Maija P. Valta, Pekka Taimen, Jani Ylä-Pelto, Laura L. Elo, Johanna Tuomela
Publikováno v:
Transl Androl Urol
BACKGROUND: Patient-derived xenografts (PDXs) are considered to better recapitulate the histopathological and molecular heterogeneity of human cancer than other preclinical models. Despite technological advances, PDX models from hormone naïve primar