Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Pirkko, Mattila"'
Autor:
Luz E Cabrera, Suvi T Jokiranta, Sanna Mäki, Simo Miettinen, Ravi Kant, Lauri Kareinen, Tarja Sironen, Jukka-Pekka Pietilä, Anu Kantele, Eliisa Kekäläinen, Hanna Lindgren, Pirkko Mattila, Anja Kipar, Olli Vapalahti, Tomas Strandin
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012368 (2024)
The severity of COVID-19 is linked to excessive inflammation. Neutrophils represent a critical arm of the innate immune response and are major mediators of inflammation, but their role in COVID-19 pathophysiology remains poorly understood. We conduct
Externí odkaz:
https://doaj.org/article/d08c9a0c6bf14abc8cfd31ca9ef6a0ed
Autor:
Salla M. Kangas, Jaakko Teppo, Maija J. Lahtinen, Anu Suoranta, Bishwa Ghimire, Pirkko Mattila, Johanna Uusimaa, Markku Varjosalo, Jani Katisko, Reetta Hinttala
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-16 (2022)
Abstract Background Transcriptomic and proteomic profiling of human brain tissue is hindered by the availability of fresh samples from living patients. Postmortem samples usually represent the advanced disease stage of the patient. Furthermore, the p
Externí odkaz:
https://doaj.org/article/01bcf4d50e8f47fa87519123d6cba3ff
Autor:
Marko Salmikangas, Maria Laaksonen, Henrik Edgren, Marco Salgado, Anu Suoranta, Pirkko Mattila, Virve Koljonen, Tom Böhling, Harri Sihto
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285524 (2023)
Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine carcinoma that is frequently divided into Merkel cell polyomavirus negative and positive tumors due their distinct genomic and transcriptomic profiles, and disease outcomes. Although some
Externí odkaz:
https://doaj.org/article/b73c83bccbc64b178f32e9e4e9d24760
Autor:
Anu Laulajainen-Hongisto, Annina Lyly, Tanzeela Hanif, Kishor Dhaygude, Matti Kankainen, Risto Renkonen, Kati Donner, Pirkko Mattila, Tuomas Jartti, Jean Bousquet, Paula Kauppi, Sanna Toppila-Salmi
Publikováno v:
Clinical and Translational Allergy, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Genome wide association studies (GWASs) have revealed several airway disease-associated risk loci. Their role in the onset of asthma, allergic rhinitis (AR) or chronic rhinosinusitis (CRS), however, is not yet fully understood. The aim of th
Externí odkaz:
https://doaj.org/article/f0157ff0c456477185741f4a342cab58
Autor:
Ashwini Kumar, Matti Kankainen, Alun Parsons, Olli Kallioniemi, Pirkko Mattila, Caroline A. Heckman
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-13 (2017)
Abstract Background RNA sequencing (RNA-seq) has become an indispensable tool to identify disease associated transcriptional profiles and determine the molecular underpinnings of diseases. However, the broad adaptation of the methodology into the cli
Externí odkaz:
https://doaj.org/article/0ae52d828a7d4dfab89cc8e7d40cfb75
Autor:
Pia Niittymäki, Mikko Arvas, Antti Larjo, Pirkko Mattila, Jarkko Ihalainen, Martti Syrjälä, Johanna Castrén, Jukka Partanen
Publikováno v:
Blood Advances, Vol 1, Iss 14, Pp 961-967 (2017)
Abstract: Measuring the concentration of capillary hemoglobin (cHb) is a standard procedure before blood donation. To further assess the time period needed for cHb recovery after blood donation and to have a more in-depth understanding of features of
Externí odkaz:
https://doaj.org/article/9ba21f4884b74d34ba093542fae34b1a
Autor:
Krister Wennerberg, Olli Kallioniemi, Kimmo Porkka, Caroline A. Heckman, Tero Aittokallio, Jonathan Knowles, Maija Wolf, Imre Västrik, Laura Turunen, Minna Suvela, Maria E. Rämet, Tero Pirttinen, Alun Parsons, Aino Palva, Satu Mustjoki, Astrid Murumägi, Pirkko Mattila, Jesus M. Lopez Marti, Muntasir Mamun Majumder, Tuija Lundán, Maija Lepistö, Anna Lehto, Sonja Lagström, Evgeny Kulesskiy, Riikka Karjalainen, Bjørn T. Gjertsen, Erkki Elonen, Pekka Ellonen, Maxim M. Bespalov, Henrikki Almusa, Agnieszka Szwajda, Samuli Eldfors, Henrik Edgren, Bhagwan Yadav, Mika Kontro, Tea Pemovska
XLSX file 452K, DSRT Oncology drug collection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3d9a1a3b523ca3e416409b924c68ae
https://doi.org/10.1158/2159-8290.22528544
https://doi.org/10.1158/2159-8290.22528544
Autor:
Krister Wennerberg, Olli Kallioniemi, Kimmo Porkka, Caroline A. Heckman, Tero Aittokallio, Jonathan Knowles, Maija Wolf, Imre Västrik, Laura Turunen, Minna Suvela, Maria E. Rämet, Tero Pirttinen, Alun Parsons, Aino Palva, Satu Mustjoki, Astrid Murumägi, Pirkko Mattila, Jesus M. Lopez Marti, Muntasir Mamun Majumder, Tuija Lundán, Maija Lepistö, Anna Lehto, Sonja Lagström, Evgeny Kulesskiy, Riikka Karjalainen, Bjørn T. Gjertsen, Erkki Elonen, Pekka Ellonen, Maxim M. Bespalov, Henrikki Almusa, Agnieszka Szwajda, Samuli Eldfors, Henrik Edgren, Bhagwan Yadav, Mika Kontro, Tea Pemovska
PDF file 400K, Supplementary Figures 1-9; Supplementary Tables 4-9 and Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46538d99dce5bf5e0626b55a4e516035
https://doi.org/10.1158/2159-8290.22528547
https://doi.org/10.1158/2159-8290.22528547
Autor:
Ying Yu, Wanwan Hou, Haiyan Wang, Lianhua Dong, Yaqing Liu, Shanyue Sun, Jingcheng Yang, Zehui Cao, Peipei Zhang, Yi Zi, Zhihui Li, Ruimei Liu, Jian Gao, Qingwang Chen, Naixin Zhang, Jingjing Li, Luyao Ren, He Jiang, Jun Shang, Sibo Zhu, Xiaolin Wang, Tao Qing, Ding Bao, Bingying Li, Bin Li, Chen Suo, Yan Pi, Xia Wang, Fangping Dai, Andreas Scherer, Pirkko Mattila, Jinxiong Han, Lijun Zhang, Hui Jiang, Danielle Thierry-Mieg, Jean Thierry-Mieg, Wenming Xiao, Huixiao Hong, Weida Tong, Jing Wang, Jinming Li, Xiang Fang, Li Jin, Joshua Xu, Feng Qian, Rui Zhang, Yuanting Zheng, Leming Shi
As an indispensable tool for transcriptome-wide analysis of differential gene expression, RNA sequencing (RNAseq) has demonstrated great potential in clinical applications such as companion diagnostics and prognostics. However, there is a lack of cer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::733688d706267b48d6b13f17e040a3d2
https://doi.org/10.21203/rs.3.rs-2213020/v1
https://doi.org/10.21203/rs.3.rs-2213020/v1
Autor:
Disha Malani, Satu Mustjoki, Olli Lohi, Matti Kankainen, Kirsi J. Granberg, Olli Dufva, Mikko A. I. Keränen, Markus Vähä-Koskela, Merja Heinäniemi, Bishwa Ghimire, Matti Nykter, Sirpa Leppä, Ashwini Kumar, Leo Meriranta, Pirkko Mattila, Petri Pölönen, Juha Mehtonen, Suvi-Katri Leivonen, Krister Wennerberg, Oscar Brück, Jay Klievink, Sanna Siitonen, Jani Huuhtanen, Caroline A. Heckman, Jenni Lahtela
Publikováno v:
Cancer Cell. 38:424-428
Understanding factors that shape the immune landscape across hematological malignancies is essential for immunotherapy development. We integrated over 8,000 transcriptomes and 2,000 samples with multilevel genomics of hematological cancers to investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ff4ee7a109e3a2aac727d48bd4b02f
https://doi.org/10.1016/j.ccell.2020.08.019
https://doi.org/10.1016/j.ccell.2020.08.019