Phosphorylcholine-carbohydrate-protein conjugates efficiently induce hapten-specific antibodies which recognize both Streptococcus pneumoniae and Neisseria meningitidis: a potential multitarget vaccine against respiratory infections

Autor: Bay, Sylvie, Huteau, Valérie, Zarantonelli, Maria-Leticia, Pires, René, Ughetto-Monfrin, Joël, Taha, Muhamed-Kheir, England, Patrick, Lafaye, Pierre

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 2004, 47 (16), pp.3916-9. ⟨10.1021/jm040783p⟩
Journal of Medicinal Chemistry, American Chemical Society, 2004, 47 (16), pp.3916-9. ⟨10.1021/jm040783p⟩

International audience; Phosphorylcholine (ChoP) is commonly expressed at the surface of pathogens of the respiratory tract, including Streptococcus pneumoniae and Neisseria meningitidis. We designed a synthetic hapten comprising ChoP and part of its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::58f087c462e56173a02b199803c41830
https://pubmed.ncbi.nlm.nih.gov/15267227

A model of meningococcal bacteremia after respiratory superinfection in influenza A virus-infected mice

Autor: Alonso, Jean-Michel, Guiyoule, Annie, Zarantonelli, Maria Leticia, Ramisse, Françoise, Pires, René, Antignac, Aude, Deghmane, Ala Eddine, Huerre, Michel, van der Werf, Sylvie, Taha, Muhamed-Kheir

Publikováno v: FEMS Microbiology Letters; May2003, Vol. 222 Issue 1, p99, 8p