Effect of stimulus intensity on the profile of anticonvulsant activity of phenytoin, ethosuximide and valproate.

Autor: Piredda, S G, Woodhead, J H, Swinyard, E A

Publikováno v: The Journal of Pharmacology and Experimental Therapeutics; March 1985, Vol. 232 Issue: 3 p741-745, 5p

The contribution of Na V 1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and Na V 1.6 gain-of-function (GOF) mouse seizure control.

Autor: Johnson JP Jr; Department of In Vitro Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Focken T; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Karimi Tari P; Department of In Vivo Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Dube C; Department of In Vivo Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Goodchild SJ; Department of In Vitro Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Andrez JC; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Bankar G; Department of In Vivo Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Burford K; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Chang E; Department of In Vitro Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Chowdhury S; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Christabel J; Department of In Vitro Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Dean R; Department of In Vitro Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., de Boer G; Department of Compound Properties, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Dehnhardt C; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Gong W; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Grimwood M; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Hussainkhel A; Department of In Vitro Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Jia Q; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Khakh K; Department of In Vitro Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Lee S; Department of Compound Properties, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Li J; Department of In Vitro Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Lin S; Department of In Vitro Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Lindgren A; Department of Compound Properties, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Lofstrand V; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Mezeyova J; Department of In Vitro Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Nelkenbrecher K; Department of In Vivo Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Shuart NG; Department of In Vitro Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Sojo L; Department of Compound Properties, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Sun S; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Waldbrook M; Department of In Vivo Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Wesolowski S; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Wilson M; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Xie Z; Department of In Vitro Biology, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Zenova A; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Zhang W; Department of Chemistry, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Scott FL; Neurocrine Biosciences, San Diego, California, USA., Cutts AJ; Scientific Affairs, Xenon Pharmaceuticals, Inc, Burnaby, British Columbia, Canada., Sherrington RP; Executive Team, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Winquist R; Executive Team, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Cohen CJ; Executive Team, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada., Empfield JR; Executive Team, Xenon Pharmaceuticals Inc, Burnaby, British Columbia, Canada.

Publikováno v: British journal of pharmacology [Br J Pharmacol] 2024 Oct; Vol. 181 (20), pp. 3993-4011. Date of Electronic Publication: 2024 Jun 24.

Stimulation-Dependent Effect of Antiepileptic Drugs in Amygdala Kindled Rats on Both Seizure Score and Duration of Afterdischarges.

Autor: Voits, Mechthild, Frey, Hans-Hasso

Publikováno v: Pharmacology & Toxicology; 1994, Vol. 75 Issue 1, p54-61, 8p

Neurobiology of Epilepsy and Aging

Autor: Ramsay, Eugene

This volume in the International Review of Neurobiology series addresses the epidemiology, pathophysiology, and treatment of epilepsy in elderly patients. Demographically, the elderly comprise both the fastest-growing segment of the U.S. population a

Making the Prozac Decision : A Guide to Antidepressants

Autor: Turkington, Carol, Kaplan, Eliot F.