Výsledky vyhledávání - "Piqueras, L."

Beneficial effects of PCSK9 inhibition with alirocumab in familial hypercholesterolemia involve modulation of new immune players

Autor: Marques P, Domingo E, Rubio A, Martinez-Hervas S, Ascaso J, Piqueras L, Real J, Sanz M

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
Consejo Superior de Investigaciones Científicas (CSIC)

Familial hypercholesterolemia (FH) is associated with low-grade systemic inflammation, a key driver of premature atherosclerosis. We investigated the effects of inhibiting proprotein convertase subtilisin/kexin type 9 (PCSK9) function on inflammatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::3700846662d8bd2da2ee43f05e2c890c
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=16319

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Association of chemokines IP-10/CXCL10 and I-TAC/CXCL11 with insulin resistance and enhance leukocyte endothelial arrest in obesity

Autor: Moreno B, Hueso L, Ortega R, Benito E, Sergio Martinez H, Peiro M, Civera M, Sanz M, Piqueras L, Real J

Publikováno v: MICROVASCULAR RESEARCH
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname

BACKGROUND AND AIMS: Obesity is a key contributing factor to incidental type 2 diabetes and cardiovascular disease. CXCR3 receptor and its ligands CXCL 10 and 11 are associated with atherosclerosis and cardiovascular disease. The aim of our study was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::86550f7b8c845669eef47cdd9aab0193
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15983

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Postprandial triglyceridemia is modulated by insulin resistance but not by grade of obesity in abdominal and morbid obese subjects

Autor: Moreno-Perez B, Benito E, Civera M, Alabadi B, Martinez-Hervas S, Peiro M, Gonzalez-Navarro H, Piqueras L, Jesus Sanz M, Ascaso J, Real J

Publikováno v: INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname

BACKGROUND: Obesity is associated with high cardiovascular risk. Postprandial lipidemia has been associated with cardiovascular disease risk. Our aim was to identify whether anthropometric parameters, insulin resistance (IR) and/or fasting plasma tri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::727348353b782e673c9f759a0b1bbcf9
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15059

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Peripheral blood levels of CXCL10 are a useful marker for diabetic polyneuropathy in subjects with type 2 diabetes

Autor: Ascaso P, Palanca A, Martinez-Hervas S, Sanz M, Ascaso J, Piqueras L, Real J

Publikováno v: INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname

BACKGROUND: Diabetic peripheral neuropathy (DPN) is a chronic complication of diabetes mellitus associated with high morbidity and mortality. Major risk factors for DPN include metabolic changes, duration of diabetes, nerve ischaemia and derangements

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::57410d0f05cdbd8c6146447da17be4ec
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15704

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Oral Unsaturated Fat Load Impairs Postprandial Systemic Inflammation in Primary Hypercholesterolemia Patients

Autor: Collado A, Domingo E, Marques P, Perello E, Martinez-Hervas S, Piqueras L, Ascaso J, Real J, Sanz M

Publikováno v: Frontiers in Pharmacology
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
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Context: Primary hypercholesterolemia (PH) is a lipid disorder characterized by elevated levels of cholesterol and low-density lipoprotein (LDL). Low-grade systemic inflammation is associated with PH, which might explain the higher incidence of cardi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::d02f02d1f545887cce4bdda9d2adb749
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15951

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Primary hypercholesterolemia and development of cardiovascular disorders: cellular and molecular mechanisms involved in low-grade systemic inflammation and endothelial dysfunction

Autor: Collado A, Domingo E, Piqueras L, Sanz M

Publikováno v: The International Journal Of Biochemistry & Cell Biology
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname

Primary hypercholesterolemia, a metabolic disorder characterized by elevated circulating levels of cholesterol products, mainly low-density lipoproteins, is associated with arteriosclerosis development. Cardiovascular disease, predominantly myocardia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::49eb7480975988c257b2b509d3e8f84f
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15935

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The nuclear retinoid-related orphan receptor RORalpha controls adipose tissue inflammation in patients with morbid obesity and diabetes

Autor: Ortega R, Hueso L, Benito E, Ortega J, Civera M, Sanz M, Real J, Piqueras L

Publikováno v: International journal of obesity (2005)
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
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BACKGROUND/AIMS: Inflammation governs adipose tissue (AT) dysfunction in obesity. Retinoic acid receptor-related orphan receptor alpha (RORalpha) is associated with inflammation and insulin resistance in animal studies, but its role in human obesity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::0cb840b773c3799ce337a446aca29504
https://www.fundanet.incliva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15626

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